Drug toxicity; new research.9781604563207 Drug toxicity; new research. Ed. by Cam E. Vellotis. Nova Science Publishers 2008 330 pages $98.00 Hardcover RA1238 Following a brief introduction to drug toxicity as systemic effects that may occur with overdosage of a medication, accumulation of the drug in the body over time, or the inability of a patient's body to eliminate the drug, international scientists present recent research trends in this field. The first of eight chapters examines the pharmaceutical industry's use of new methods, under regulatory pressure, to detect drug toxicity earlier in the development and clinical trial process. Contributors treat toxicity issues relating to specific classes of drugs (e.g., antipsychotics Antipsychotics A class of drugs used to control psychotic symptoms in patients with psychotic disorders such as schizophrenia and delusional disorder. Antipsychotics include risperidone (Risperdal), haloperidol (Haldol), and chlorpromazine (Thorazine). , topical corticosteroids Topical corticosteroids Cortisone and related drugs used on the skin and in the eye, usually for allergic conditions. Mentioned in: Corneal Ulcers , COX-2 inhibitors Cox-2 Inhibitors Definition Cox-2 inhibitors are non-steroidal anti-inflammatory drugs (NSAIDs) which selectively inhibit cyclooxygenase-2. The cyclooxygenases are required for the creation of prostaglandins. ); and the perplexing per·plex tr.v. per·plexed, per·plex·ing, per·plex·es 1. To confuse or trouble with uncertainty or doubt. See Synonyms at puzzle. 2. To make confusedly intricate; complicate. question of why the amino acid D-Serine is nephrotoxic nephrotoxic /neph·ro·tox·ic/ (nef´ro-tok?sik) destructive to kidney cells. Nephrotoxic Toxic, or damaging, to the kidney. in some experimental animals but not others. The editor's credentials are not stated. ([c]20082005 Book News, Inc., Portland, OR) |
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