Drug cuts risk of seizures in pregnancy. (Biomedicine).New data from a massive international research effort indicate that an inexpensive drug treatment lessens the risk of seizures that sometimes strike and even kill women during pregnancy or immediately after delivery. The finding could stimulate efforts to make the anticonvulsant an drug, magnesium sulfate  ti·con·vul sive (-s v) adj.1. A salt or ester of sulfuric acid. 2. The bivalent group SO4. 3. A chemical compound containing such a group. v. more widely available and more routinely used. 1. To treat or react with sulfuric acid or a sulfate. 2. To become sulfated. Worldwide, an estimated 50,000 pregnant women die each year from complications related to preeclampsia pre , a condition of elevated blood pressure and protein buildup in urine that develops during some pregnancies. This occasionally results in eclampsia e·clamptic (-tk) adj.uremic eclampsia that due to uremia. e·clamp·si·a ( -kl mps, including seizures that can be lethal. In some countries including the United States, anticonvulsants have long been prescribed to preeclamptic women. A dearth of data on various drugs' effectiveness, however, has given rise to inconsistent and spotty treatment. To test the effectiveness of magnesium sulfate, the Magpie magpie, common name for certain birds of the family Corvidae (crows and jays). The black-billed magpie, Pica pica, of W North America has iridescent black plumage, white wing patches and abdomen, and a long wedge-shaped tail. It is altogether about 20 in. (50 cm) long. Magpies build large, domed nests in trees. Nest-building is part of courtship. The female alone incubates the eggs. Trial Collaborative Group, a research team of scientific and medical personnel from 175 hospitals in 33 countries, studied 10,141 women with preeclampsia. Half the women received magnesium sulfate by injection or infusion in the hospital over about 24 hours, and the rest got a placebo. While 96 placebo takers developed eclampsia and 20 of them died, just 40 women receiving the drug experienced eclamptic seizures and just 11 of these died, the researchers report in the June 1 Lancet. The rate of survival among the women's babies was unaffected. The new study "strengthens beyond reasonable doubt reasonable doubt n. not being sure of a criminal defendant's guilt to a moral certainty. Thus, a juror (or judge sitting without a jury) must be convinced of guilt of a crime (or the degree of crime, as murder instead of manslaughter) "beyond a reasonable doubt," and the jury will be told so by the judge in the jury instructions. However, it is a subjective test since each juror will have to decide if his/her doubt is reasonable." the evidence that magnesium sulfate reduces the risk of eclampsia among preeclamptic women, conclude Shirish S. Sheth of the Navjivan Society in Mumbai, India, and lain Chalmers of the U.K. Cochrane Centre in Oxford, England, in a commentary published with the study. They argue that the finding places a burden of responsibility on international organizations to make magnesium sulfate generally available in poor countries.--B.H. |
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