Detect antiviral-resistant virus strands.A new Cytomegalovirus cytomegalovirus (sī'təmĕg'əlōvī`rəs), member of the herpesvirus family that can cause serious complications in persons with weakened immune systems. (CMV CMV cytomegalovirus. CMV abbr. 1. controlled mechanical ventilation 2. cytomegalovirus Cytomegalovirus (CMV) ) Antiviral Resistance Test accurately detects in three days or less key genetic mutations associated with antiviral resistance to CMV; most other tests' TAT is up to two weeks. The molecular test accurately detects key genetic mutations by sequencing the CMV UL97 phosphotransferase gene and the CMV UL54 DNA polymerase DNA polymerase /DNA po·lym·er·ase/ (pah-lim´er-as) any of various enzymes catalyzing the template-directed incorporation of deoxyribonucleotides into a DNA chain, particularly one using a DNA template. gene. Mutations in the UL97 phosphotransferase gene have been associated with ganciclovir resistance. Mutations in the UL54 DNA polymerase gene have been associated with resistance to the medications ganciclovir, foscarnet foscarnet /fos·car·net/ (fos-kahr´net) a virostatic agent used as the sodium salt in the treatment of cytomegalovirus retinitis and herpes simplex in immunocompromised patients. , and cidofovir. [ILLUSTRATION OMITTED] ViraCor Laboratories Visit www.rsleads.com/906ml-180 |
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