Design Continuum Delivers Five New Instruments to U.S. Genomics; Trilogy Single Molecule Analyzers to be Placed in Top Life Sciences Research Labs.To download high-resolution, print-ready JPEG JPEG in full Joint Photographic Experts Group Standard computer file format for storing graphic images in a compressed form for general use. JPEG images are compressed using a mathematical algorithm. images, click on the thumbnail image above. WARNING: these images are very large (800K+) Click here for caption Photo Editors/Business Editors/Health/Medical Writers MULTIMEDIA AVAILABLE: http://www.businesswire.com/cgi-bin/mmg.cgi?eid=4535338 BOSTON--(BUSINESS WIRE)--Dec. 16, 2003 Design Continuum  This article or section is written like an .Please help [ rewrite this article] from a neutral point of view. Mark blatant advertising for , using . Inc. today announced it has delivered five Trilogy Single Molecule Analyzers to U.S. Genomics in Woburn, Mass. In the first quarter of 2004, the second generation, single molecule analysis machines will be placed in some of the country's leading genetics research labs. The new machines improve on their predecessors by increasing the rate of sample throughput from 50 to 500 samples per day, which decreases the cost per test and will speed researchers in their study of diseases, their origins and pathways. Using U.S. Genomics' patented technology, the Trilogy Single Molecule Analyzer enables life scientists to detect and analyze a diverse array of biological molecules including DNA DNA: see nucleic acid. DNA or deoxyribonucleic acid One of two types of nucleic acid (the other is RNA); a complex organic compound found in all living cells and many viruses. It is the chemical substance of genes. , RNA RNA: see nucleic acid. RNA in full ribonucleic acid One of the two main types of nucleic acid (the other being DNA), which functions in cellular protein synthesis in all living cells and replaces DNA as the carrier of genetic and proteins. "These new Single Molecule Analysis instruments build on Design Continuum's strength as an engineering partner capable of designing systems that make complex technologies easy to use," said Stephen P. DeFalco, Chairman and Chief Executive Officer, U.S. Genomics. "The Trilogy Instruments will enable life sciences researchers to directly analyze and quantitate quan·ti·tate tr.v. quan·ti·tat·ed, quan·ti·tat·ing, quan·ti·tates To determine or measure the quantity of. [Back-formation from quantitative (analysis). single molecules of DNA, RNA and proteins without amplification, saving time and cost." Engineering Challenges To productize U.S. Genomics' sophisticated scientific analysis system, Design Continuum's engineers and designers first visited academic and pharmaceutical research labs to measure the space available and to observe the needs of researchers working with lab equipment. They considered how the machine fits into the workflow of a lab and what other equipment is used in the vicinity. They then created a freestanding workstation designed for easy installation and use within a lab environment, and reconfigured the single molecule analysis system to fit inside the enclosure. This required building in vibration control to stabilize the optics, ensuring thermal stability by keeping heat sources away from the optics, and aligning the optics by folding the five laser beams in each machine with a series of mirrors. Using motion control and automation technologies, Design Continuum's engineers designed a sample delivery system that makes it easier for researchers to place samples into the machine. Once the samples are placed, computer controls automatically move the samples precisely through the analysis process. The sample delivery system is carefully calibrated cal·i·brate tr.v. cal·i·brat·ed, cal·i·brat·ing, cal·i·brates 1. To check, adjust, or determine by comparison with a standard (the graduations of a quantitative measuring instrument): with the optical systems to provide precision analysis and maximum sample throughput. "U.S. Genomics presented our team with the type of engineering challenges that most engineers would love to work on," said Mark West, Principal Mechanical Engineer at Design Continuum. "This project had all of the elements that keep engineers thinking through the night - mechanics, optics, fluidics fluidics, branch of engineering and technology concerned with the development of equivalents of various electronic circuits using movements of fluid rather than movements of electric charge. and electronics - all to enable a technology platform that is moving life sciences researchers closer to realizing breakthrough therapies for the healthcare industry." About U.S. Genomics, Inc. U.S. Genomics is a leading marketer and developer of technologies that allow genetics, functional genomics Noun 1. functional genomics - the branch of genomics that determines the biological function of the genes and their products genomics - the branch of genetics that studies organisms in terms of their genomes (their full DNA sequences) , and diagnostic analysis to be performed at the single molecule level. The company's GeneEngine(TM) technology platform can analyze individual molecules of DNA, RNA, and proteins without the need for amplification and combines advances in nanofluidics, optical engineering, and novel labeling strategies. The technology has life sciences applications in the areas of research, drug discovery and development, and diagnostics, and longer term it will provide a platform to advance our understanding of diseases in order to tailor drug development. Founded in 1997, U.S. Genomics is located in Woburn, Massachusetts Woburn (/'wu.bə(r)n/) is a city in Middlesex County, Massachusetts, USA. The population was 37,258 at the 2000 census. Woburn is the birthplace of Anglo-American scientist Benjamin Thompson, a.k.a. . For more information, please visit www.usgenomics.com. About Design Continuum, Inc. Design Continuum designs the products and brands that people love to use. Since 1983, the company has helped businesses worldwide drive tangible business value through design. With locations in Boston, Milan and Seoul, Design Continuum's clients include Andersen Windows Andersen Corporation is a privately-owned business that was founded in 1903 by Danish immigrant Hans Andersen and his family in Hudson, Wisconsin, where logs arrived via the St. Croix River. , BMW BMW in full Bayerische Motoren Werke AG German automaker. Founded as an aircraft engine manufacturer in 1916, the company assumed the name Bayerische Motoren Werke and became known for its high-speed motorcycles in the 1920s. , General Motors, Master Lock, Moen, Procter & Gamble, Samsung, TOTO Toto pet terrier who accompanies Dorothy to Oz. [Am. Lit.: The Wonderful Wizard of Oz] See : Dogs (programming) toto - /toh-toh'/ The default scratch file name among French-speaking programmers - in other words, a francophone foo. USA and medical companies including Aspect Medical Systems and Roche Diagnostics. For more information, visit www.dcontinuum.com, e-mail info@dcontinuum.com or call (800) 625-5115. All trademarks, service marks and company names are the property of their respective owners. MULTIMEDIA AVAILABLE: http://www.businesswire.com/cgi-bin/mmg.cgi?eid=4535338 |
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