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Demand for Enlarged Prostate Treatments Expected to Rise Sharply.


Positive Trial Results for Nymox's (NASDAQ NASDAQ
 in full National Association of Securities Dealers Automated Quotations

U.S. market for over-the-counter securities. Established in 1971 by the National Association of Securities Dealers (NASD), NASDAQ is an automated quotation system that reports on
:NYMX NYMX New York Mercantile Exchange ) NX-1207 Drug Treatment for Enlarged Prostate Enlarged Prostate Definition

A non-cancerous condition that affects many men past 50 years of age, enlarged prostate makes urinating more difficult by narrowing the urethra, a tube running from the bladder through the prostate gland.
 

HASBROUCK HEIGHTS, N.J. -- Changing demographics and attitudes towards health will drive the demand for new and effective treatments for enlarged prostate in the maturing male baby boomer population, according to Brian Doyle, Senior Manager for Worldwide Sales and Marketing for Nymox Pharmaceutical Corporation (NASDAQ:NYMX). Enlarged prostate or benign prostatic hyperplasia benign prostatic hyperplasia
n. Abbr. BPH
A nonmalignant enlargement of the prostate gland commonly occurring in men after the age of 50, and sometimes leading to compression of the urethra and obstruction of the flow of urine.
 (BPH BPH
abbr.
benign prostatic hyperplasia


BPH
Benign prostatic hypertrophy, a very common noncancerous cause of prostatic enlargement in older men.
) is currently the fourth most commonly diagnosed ailment of men over the age of 50 in the U.S. (Am J Manag Care. 2006;12(4 Suppl):S83-9). In 2000 alone approximately 4.5 million visits were made to physician offices for a primary diagnosis of BPH (Urological Diseases in America Chapter 2, Benign Prostatic Hyperplasia, National Institutes of Health). This number is expected to rise sharply as the men of the baby boomer generation enter their 50s and 60s.

Nymox has developed NX-1207, an innovative new treatment for BPH. The company's recently completed Phase 2 trial showed positive efficacy and safety results for NX-1207. Overall, patients treated with NX-1207 showed mean improvement of 9.35 points in AUA AUA American Urological Association, see there  Symptom Score values, the standard scale used to evaluate BPH drugs and treatments. This improvement compares favorably to the 3.5 to 5 point reported in published studies of currently approved drugs for BPH and reached statistical significance when compared to placebo. Subjects treated with NX-1207 also showed an overall significant reduction in mean prostate volume. The results of the trial demonstrated the excellent safety and side effect profile of NX-1207. Subjects treated with NX-1207 had no serious side effects Side effects

Effects of a proposed project on other parts of the firm.
. In particular, patients given NX-1207 had no (0%) significant sexual side effects. Serious adverse events occurred in 5.1% of all placebo patients, and in 0% of the NX-1207 treated group.

"The demand for effective treatments for BPH will be driven not only by the increase in the total number of men with BPH but also by the changing attitudes towards health in the baby boomer generation," said Brian Doyle. "Increasingly, men enter their 50s and 60s expecting to maintain their level of health and activity. BPH represents a challenge to those expectations, both in terms of lifestyle and physical health. Current treatments either are not very effective or carry risks of serious side effects or both. There is a pressing unmet need for a convenient and effective treatment of this common affliction of men."

BPH afflicts approximately half of men over age 50 and close to 90% of men by age 80. The disorder causes difficulties with urination urination

Process of excreting urine from the bladder (see urinary system). Nerve centres in the spinal cord, brain stem, and cerebral cortex control it through involuntary and voluntary muscles. The need to void is felt when the bladder holds 3.
 associated with aging, such as urination at night, urge to void frequently, hesitancy hes·i·tan·cy
n.
An involuntary delay or inability in starting the urinary stream.
, weak stream, and other problems.

More information about Nymox is available at www.nymox.com, email: info@nymox.com, or 800-936-9669.

This press release contains certain "forward-looking statements" as defined in the United States Private Securities Litigation Reform Act The Private Securities Litigation Reform Act of 1995 (PSLRA) implemented several significant substantive changes affecting certain cases brought under the federal securities laws, including changes related to pleading, discovery, liability, class representation and awards fees and  of 1995 that involve a number of risks and uncertainties. There can be no assurance that such statements will prove to be accurate and the actual results and future events could differ materially from management's current expectations. The conduct of clinical trials and the development of drug products involve substantial risks and uncertainties and actual results may differ materially from expectations. Promising early results do not ensure that later stage or larger scale clinical trials will be successful or will proceed as expected. Such factors are detailed from time to time in Nymox's filings with the United States Securities and Exchange Commission and other regulatory authorities.
COPYRIGHT 2006 Business Wire
No portion of this article can be reproduced without the express written permission from the copyright holder.
Copyright 2006, Gale Group. All rights reserved. Gale Group is a Thomson Corporation Company.

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Publication:Business Wire
Date:Oct 17, 2006
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