Debriding ointment.Smith & Nephew Wound Management's Gladase[TM], a papain-urea debriding ointment, is now covered by Medicaid in all 50 states. Gladase uses papain papain: see papaya. , a proteolytic enzyme derived from papayas, and urea, a denaturant denaturant a denaturing agent. of proteins, to remove necrotic tissue and liquefy liquefy /liq·ue·fy/ (lik´wi-fi) to become or cause to become liquid. slough in acute wounds, chronic wounds, infected wounds, carbuncles, and burns. Removing necrotic tissue from the wound bed with Gladase is the first step in Wound Bed Preparation, the evidence-based approach to wound healing wound healing Physiology The repair of a wound Steps Inflammation, repair and closure, remodeling, final healing; repair of incisions may be either simple–'clean' wounds with little loss of tissue heal by 'primary intention', or 'dirty' wounds heal by supported by Smith & Nephew. [ILLUSTRATION OMITTED] CIRCLE 86 ON READER SERVICE CARD |
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