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Danish Institute of Agricultural Sciences Expands TimeLogic DeCypher Solution to Accommodate Large Analysis Needs for Farm Animal Genome Sequencing Projects.


Business Editors/Health/Medical Writers

BIOWIRE2K

CRYSTAL BAY, Nev. & TJELE, Denmark--(BUSINESS WIRE)--March 24, 2003

DeCypher Implemented as Data Mining Gateway for

International Genome Projects genome project 1 The Human Genome Project, see there 2. A general term for a coordinated research initiative for mapping and sequencing the genome of any organism  

The Ministry of Food, Agriculture and Fisheries' Danish Institute of Agricultural Sciences has doubled capacity of their TimeLogic(TM) DeCypher(R) Accelerated Bioinformatics Solution for key domesticated do·mes·ti·cate  
tr.v. do·mes·ti·cat·ed, do·mes·ti·cat·ing, do·mes·ti·cates
1. To cause to feel comfortable at home; make domestic.

2. To adopt or make fit for domestic use or life.

3.
a.
 animal genomic analysis projects. Relying upon accelerated FPGA (Field Programmable Gate Array) A type of gate array that is programmed in the field rather than in a semiconductor fab. Containing up to hundreds of thousands of gates, there are a variety of FPGA architectures on the market.  hardware rather than a collection of general purpose CPUs, DeCypher enables scientists to run complex biocomputing Biocomputing can mean at least two different things:
  • First, it can be defined as the construction and use of computers which function like living organisms or contain biological components, so-called biocomputers. In this meaning it is closely related to DNA computing.
 searches in days instead of multiple months.

With their goal of improving disease resistance and constitution for cattle and pigs, DIAS relies heavily on genetic technology to better understand the genomes of key agricultural animals. Identification of genetic markers for health and production traits -- as well as mapping of hereditary defects -- is achieved through exhaustive comparisons between multiple genomes. These techniques require tremendous computing capacity.

"DIAS originally implemented DeCypher in 2001, and it has efficiently addressed our large bioinformatics computing demands," commented Dr. Christian Bendixen, Chief scientist in the Department of Animal Breeding and Genetics. "As we undertake new and larger EST EST electroshock therapy.

EST
abbr.
electroshock therapy
 and genome sequencing projects in conjunction with international partners such as the Beijing Genomics Institute The Beijing Genomics Institute (BGI) was founded in 1998. It achieved international prominence as a center for sequencing the human genome. BGI completed one percent of the human genome for the Human Genome Project. , we are faced with the challenge of analyzing and annotating an·no·tate  
v. an·no·tat·ed, an·no·tat·ing, an·no·tates

v.tr.
To furnish (a literary work) with critical commentary or explanatory notes; gloss.

v.intr.
To gloss a text.
 millions of genomic and cDNA sequences. TimeLogic's DeCypher system will provide a gateway for mining this sequence data, and the added capacity will greatly expand our comparative genome analysis capabilities," he added.

Rick MacDonald, TimeLogic President, remarked, "DeCypher speeds the core algorithms needed by DIAS -- BLAST, Smith-Waterman, and Hidden Markov Model A hidden Markov model (HMM) is a statistical model in which the system being modeled is assumed to be a Markov process with unknown parameters, and the challenge is to determine the hidden parameters from the observable parameters.  analysis -- with the performance of hundreds to thousands of CPUs. We are pleased that the system has proven to be a robust and efficient computing technology, and that the upgrade will further international collaboration for key, large-scale agricultural genomics projects."

About TimeLogic

DeCypher enables researchers to tackle biocomputing projects economically, without driving up power, cooling, and maintenance costs. As TimeLogic's unique solution is integrated to speed bioinformatics computation, the utility of a customer's existing computing hardware is maximized as these CPUs are freed to address additional mission critical applications. DeCypher is utilized by over 50 top biotechnology, pharmaceutical, and agribusiness agribusiness

Agriculture operated by business; specifically, that part of a modern national economy devoted to the production, processing, and distribution of food and fibre products and byproducts.
 companies, and academic and government research institutions worldwide. Accelerating the pace of bioinformatics discovery with DeCypher since 1996, TimeLogic is headquartered at 22 State Route 28, Crystal Bay, NV 89402-0248. For more information, please contact Christopher Hoover, Director of Marketing (Tel: 775/832-3104, chrish@timelogic.com) or visit http://www.timelogic.com.

About DIAS

The Danish Institute of Agricultural Sciences (DIAS) is a sector research institution under the Ministry of Food, Agriculture and Fisheries fisheries. From earliest times and in practically all countries, fisheries have been of industrial and commercial importance. In the large N Atlantic fishing grounds off Newfoundland and Labrador, for example, European and North American fishing fleets have long . DIAS aims to conduct research and accumulate knowledge of importance to agriculture. Emphasis is on responsible resource utilization, environmental impacts both internal and external, animal welfare, and the quality and competitiveness of the products. With its approximately 1,125 employees DIAS is one of the largest research institutions in Denmark. Integrating animal husbandry animal husbandry, aspect of agriculture concerned with the care and breeding of domestic animals such as cattle, goats, sheep, hogs, and horses. Domestication of wild animal species was a crucial achievement in the prehistoric transition of human civilization from , plant production and technical research enables DIAS to embrace a broad range of agricultural areas, and to apply both discipline and holistic approaches within these areas. The Department of Animal Breeding and Genetics is located at Research Center Foulum at Blichers Alle K25, DK-8830 Tjele, Denmark. For more information please contact Dr. Christian Bendixen, Chief Scientist (Tel: +45 8999 1356 -- Fax + 45 8999 1300, E-mail: christian.bendixen@agrsci.dk).
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Publication:Business Wire
Date:Mar 24, 2003
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