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Dade Behring Signs License Agreement with Euro-Diagnostica for Rights to Cyclic Citrullinated Peptides (CCP).


New automated test for rheumatoid arthritis rheumatoid arthritis

Chronic, progressive autoimmune disease causing connective-tissue inflammation, mostly in synovial joints. It can occur at any age, is more common in women, and has an unpredictable course.
 to be developed

DEERFIELD, Ill. -- Dade Behring Inc.(NASDAQ NASDAQ
 in full National Association of Securities Dealers Automated Quotations

U.S. market for over-the-counter securities. Established in 1971 by the National Association of Securities Dealers (NASD), NASDAQ is an automated quotation system that reports on
:DADE), the world's largest company solely dedicated to clinical diagnostics, today announced that it has signed a license and cooperation agreement with Euro-Diagnostica, a company specializing in autoimmune disease autoimmune disease, any of a number of abnormal conditions caused when the body produces antibodies to its own substances. In rheumatoid arthritis, a group of antibody molecules called collectively RF, or rheumatoid factor, is complexed to the individual's own gamma  testing, granting rights to Dade Behring for the use of cyclic citrullinated peptides (CCP (Certified Computer Professional) The award for successful completion of a comprehensive examination on computers offered by the ICCP. See ICCP and certification.
.

1. (language) CCP - Concurrent Constraint Programming.
2.
). Euro-Diagnostica will contribute know-how and key raw materials for the development of an automated anti-CCP test for use on Dade Behring's clinical laboratory instrumentation.

Several studies1 have shown that anti-CCP tests are more specific than rheumatoid factor rheumatoid factor
n. Abbr. RF
Any of the immunoglobulins found in the serum of individuals with rheumatoid arthritis that enhance the agglutination of suspended particles that are coated with pooled human gamma globulin and that are used
 tests for diagnosing rheumatoid arthritis--the most common type of autoimmune arthritis. Today, rheumatoid arthritis is considered difficult to diagnose because patients' symptoms can vary and physicians commonly rely on multiple tests before making a diagnosis.

"Dade Behring is committed to improving the quality of health care for patients throughout the world," said Jim Reid-Anderson, Chairman, President and CEO (1) (Chief Executive Officer) The highest individual in command of an organization. Typically the president of the company, the CEO reports to the Chairman of the Board. , Dade Behring. "Through this agreement, we have the potential to provide clinical laboratory customers access to a diagnostic test which will allow them to better serve their physicians that are treating the millions of patients affected with rheumatoid arthritis."

Early treatment of rheumatoid arthritis is important because physicians may be able to prevent patients from developing permanent damage to joints affected with arthritis.

"We are delighted to be working with such a world class partner as Dade Behring to potentially develop this important test and make it more widely available," said Peter Foster, CEO, Euro-Diagnostica.

About Dade Behring

With 2005 revenue of nearly $1.7 billion, Dade Behring is the world's largest company solely dedicated to clinical diagnostics. It offers a wide range of products, systems and services designed to meet the day-to-day needs of laboratories, delivering innovative solutions to customers and enhancing the quality of life for patients. Additional company information is available on the Internet at www.dadebehring.com.

About Euro-Diagnostica

Euro-Diagnostica is a rapidly growing, innovative diagnostics company that specializes in the development, manufacturing and marketing of tests for the diagnosis of autoimmune disease. The company has been a pioneer in the use of anti-CCP as the new test of choice for rheumatoid arthritis diagnosis. Additional company information is available on www.eurodiagnostica.com.

This press release may contain "Forward-Looking Statements forward-looking statement

A projected financial statement based on management expectations. A forward-looking statement involves risks with regard to the accuracy of assumptions underlying the projections.
" within the meaning of the Private Securities Litigation Reform Act The Private Securities Litigation Reform Act of 1995 (PSLRA) implemented several significant substantive changes affecting certain cases brought under the federal securities laws, including changes related to pleading, discovery, liability, class representation and awards fees and  of 1995. These forward statements include information regarding the intent, belief or current expectation of the company and members of its senior management team, including, without limitation, expectations regarding prospective performance and opportunities and the outlook for the company's businesses, performance, opportunities and regulatory approval. In addition, the company is in the process of a major new product launch, which involves risks and uncertainties regarding product performance, costs of introduction and support, and customer acceptance. Investors are cautioned that any such forward-looking statements are not guarantees of future performance and involve risks and uncertainties, and that actual results may differ materially from those contemplated by the company.

1. Kamoun, Malek. Diagnostic Performance and Predictive Value pre·dic·tive value
n.
The likelihood that a positive test result indicates disease or that a negative test result excludes disease.



predictive value

a measure used by clinicians to interpret diagnostic test results.
 of Anti-citrullinated Peptide Antibodies for Diagnosis of Rheumatoid Arthritis: Toward More Accurate Detection? Clinical Chemistry 51, No. 1, 2005: 12-13; Avouac J, Gossec L, Dougados M. Diagnostic and predictive value of anti-cyclic citrullinated protein antibodies in rheumatoid arthritis: a systemic literature review. Ann Rheum rheum (rldbomacm) any watery or catarrhal discharge.

rheum
n.
A watery or thin mucous discharge from the eyes or nose.



rheum

any watery or catarrhal discharge.
 Dis 2006; 65: 845-51; Sauerland, U., et al., Clinical utility of the anti-CCP assay: experiences with 700 patients. Ann N Y Acad Sci, 2005. 1050: p. 314-8; Zendman, A.J., W.J. van Venrooij, and G.J. Pruijn. Use and significance of anti-CCP autoantibodies in rheumatoid arthritis. Rheumatology rheumatology /rheu·ma·tol·o·gy/ (-tol´ah-je) the branch of medicine dealing with rheumatic disorders, their causes, pathology, diagnosis, treatment, etc.

rheu·ma·tol·o·gy
n.
 (Oxford), 2006. 45(1): p. 20-5.
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Copyright 2006, Gale Group. All rights reserved. Gale Group is a Thomson Corporation Company.

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Date:Nov 20, 2006
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