DROP DETECTED IN DEATH RATES FROM CANCER.

Byline: Jane E. Brody The New York Times

For the first time since 1900, overall cancer death rates have shown a sustained decline, a new analysis has shown.

Although death rates of some particularly deadly cancers are rising, a study of all cancer deaths from 1990 to 1995 documented the historic drop.

Experts attributed the decline to preventive measures, especially anti-smoking efforts, and to improvements in early detection and treatment, which have increased the chances of surviving many common cancers.

``This is the news we've been waiting for,'' said Dr. Richard Klausner, director of the National Cancer Institute. ``The 1990s will be remembered as the decade when we measurably turned the tide against cancer.''

The declining mortality rate, which shows signs of accelerating, suggests that the prediction that cancer deaths would overtake heart deaths early in the next century may be wrong. The death rate from heart disease, which has dropped precipitously since 1970, is still declining, but more slowly than previously.

The current analysis, to be published in the Friday issue of the journal Cancer, showed that the overall cancer mortality rate, adjusted for age, dropped each year from 1990 to 1995, for a total decline of about 3.1 percent. In 1990, the cancer death rate peaked at 135 deaths for every 100,000 people. The rate then fell annually, reaching 129.8 deaths per 100,000 in 1995, or about five fewer deaths per 100,000 people than in 1990. The study was done because analysts noticed the trend in statistics from 1994 and preliminary data from 1995.

The researchers, Dr. Philip Cole, epidemiologist at the University of Alabama School of Public Health, and Dr. Brad Rodu of the university's School of Dentistry in Birmingham, attributed the bulk of the decline to the reduction in cigarette smoking among American men, which has resulted in a ``major reduction'' in lung cancer of 3.9 percent and a decline of 2 percent in other smoking-related cancers.

Dr. Harmon Eyre, chief medical officer for the American Cancer Society, said that while lung cancer deaths continued to rise in women, the rate had slackened in recent years and was expected to decline as a result of a reduction in smoking among women.

Also contributing to the fall in mortality rates has been reduced occupational exposure to cancer-causing agents like asbestos, radon, vinyl chloride and other carcinogenic industrial substances, Eyre said.