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Cytotoxic Treatments play a Critical Role in Modern Cancer Therapy - Target-Based Approaches for Discovering Novel Oncology Drugs.


DUBLIN, Ireland -- Research and Markets (http://www.researchandmarkets.com/reports/c32154) has announced the addition of Target-Based Approaches for Discovering Novel Oncology Drugs to their offering.

Despite recent improvements in treatment, cancer remains a huge public health burden. Cytotoxic cy·to·tox·ic
adj.
Of, relating to, or producing a toxic effect on cells.



cyto·tox·ic
 treatments play a critical role in modern cancer therapy. Unfortunately, traditional cytotoxic agents are associated with significant toxicity. In an effort to discover new oncology drugs with improved clinical benefits and fewer side effects Side effects

Effects of a proposed project on other parts of the firm.
, drug developers have committed substantial resources to identifying novel cancer targets and compounds that interact with those targets. These efforts have been facilitated by a plethora of technologies developed in recent years to generate and exploit genomic and proteomic information. In this Decision Resources report, novel cancer drug targets and the drugs under development directed at these targets are reviewed.

This report looks at the following key topics:

--Human Epidermal Growth Factor Receptors This article is about a cell suface receptor. For estimated measure of kidney function (eGFR), see Glomerular filtration rate.
The epidermal growth factor receptor
 

--Bcr/abl Kinase

--The Proteasome Proteasomes are large protein complexes inside all eukaryotes and archaea, as well as in some bacteria. In eukaryotes, they are located in the nucleus and the cytoplasm.[1]  

--Apoptosis Pathways

--Cellular Proliferation proliferation /pro·lif·er·a·tion/ (pro-lif?er-a´shun) the reproduction or multiplication of similar forms, especially of cells.prolif´erativeprolif´erous

pro·lif·er·a·tion
n.
 and Survival

--Histone Deacetylase

--Angiogenesis Targets

--Outlook for Target-Based Approaches

For more information visit http://www.researchandmarkets.com/reports/c32154

Source: Decision Resources
COPYRIGHT 2006 Business Wire
No portion of this article can be reproduced without the express written permission from the copyright holder.
Copyright 2006, Gale Group. All rights reserved. Gale Group is a Thomson Corporation Company.

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Publication:Business Wire
Date:Apr 5, 2006
Words:178
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