CytoGenix and BioZone Laboratories Initiate Cooperative Alliance.Business Editors/Health/Medical Writers HOUSTON--(BUSINESS WIRE)--Aug. 6, 2003 CytoGenix Inc. (OTCBB OTCBB See OTC Bulletin Board (OTCBB). :CYGX) has completed an Agreement with BioZone Laboratories Inc. of Pittsburg, Calif., to investigate the synergy of their technologies in order to develop and test new formulations for select therapeutic categories. As part of this alliance the two companies will use BioZone's proprietary liposome liposome (lī`pəsōm', lĭp`ə–), microscopic, fluid-filled pouch whose walls are made of layers of phospholipids identical to the phospholipids that make up cell membranes. technology, QuSomes(TM), to microscopically encapsulate CytoGenix' ssDNA expression system sequences and protect them from metabolic destruction by exo- and endo-nucleases found on the skin and in the bloodstream. QuSomes(TM) are composed of a combination of lipids and lipid derivatives that serve as the envelope and delivery vehicle for the plasmid DNA. They also allow more uptake of ssDNA by the cell, and better release of ssDNA inside the cell. Dr. Sangita Ghosh, senior scientist and director of research and development at BioZone noted that this is an excellent blending of technologies. "We're confident that the use of our liposomal system will significantly enhance the delivery and uptake of the plasmids comprising the CytoGenix Expression Vector expression vector n. A vector, such as a plasmid, yeast, or animal virus genome, used to introduce foreign genetic material into a host cell in order to replicate and amplify the foreign DNA sequences as a recombinant molecule. , which will result in higher levels of production of the desired DNA sequence DNA sequence Genetics The precise order of bases–A,T,G,C–in a segment of DNA, gene, chromosome, or an entire genome. See Base pair, Base sequence analysis, Chromosome, Gene, Genome. within the cells," she said. "The Agreement with BioZone represents another step in the CytoGenix strategy directed at targeting a larger class of cells," said CytoGenix CEO (1) (Chief Executive Officer) The highest individual in command of an organization. Typically the president of the company, the CEO reports to the Chairman of the Board. Dr. Malcolm Skolnick. "We believe BioZone's QuSome(TM) technology will improve efficiency in the topical formulations we have developed as well as provide delivery capabilities that enable systemic application of our ssDNA expression system technology." BioZone Laboratories is a biopharmaceutical company that develops, manufactures and markets drug delivery systems, which enhance the performance and can limit the side effects Side effects Effects of a proposed project on other parts of the firm. , of drugs. BioZone was just granted a US patent for a new liposomal delivery system they believe will revolutionize liposome and micro-encapsulation delivery. This new system called QuSomes(TM) was developed to encapsulate a variety of drugs, proteins and peptides at a fraction of the cost of conventional liposomes Liposomes Aqueous compartments enclosed by lipid bilayer membranes; liposomes are also known as lipid vesicles. Phospholipid molecules consist of an elongated nonpolar (hydrophobic) structure with a polar (hydrophilic) structure at one end. . There are several commercially successful drugs that have been formulated with liposomes and have proven to be more effective in treating diseases with fewer side effects than traditional drug formulations. CytoGenix is a biotechnology company that develops innovative products and services based on proprietary DNA DNA: see nucleic acid. DNA or deoxyribonucleic acid One of two types of nucleic acid (the other is RNA); a complex organic compound found in all living cells and many viruses. It is the chemical substance of genes. expression technology. They have products in pre-clinical development that are new, externally applied treatments for herpes, psoriasis and inflammation. These products are based on the company's US patent for its core DNA expression discovery. SAFE HARBOR Safe Harbor 1. A legal provision to reduce or eliminate liability as long as good faith is demonstrated. 2. A form of shark repellent implemented by a target company acquiring a business that is so poorly regulated that the target itself is less attractive. : Except for statements of historical fact, the statements in this press release are forward-looking. Such statements are subject to a number of risks and uncertainties that could cause actual results to differ materially from the statements made. These factors include, but are not limited to, general economic conditions, risks associated with the acceptance of new products, competition, and other factors more fully detailed in the company's filings with the Securities and Exchange Commission. Additional information about CytoGenix and its technology can be found on the Web site at www.cytogenix.com. |
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