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CyberChemics Inc. founder presents two papers at ICANNGA.


HUNTSVILLE, Ala.--(BW HealthWire)--April 1, 1997--CyberChemics Inc. (CCI CCI Chambre de Commerce et d'Industrie (France)
CCI CAM (Complementary and Alternative Medicine) Citation Index
CCI Chamber of Commerce and Industry (Western Australia) 
) Tuesday announced the participation of scientists from the company, including one of its founders, Dr. David Noever, at the International Conference on Artificial Neural Networks and Genetic Algorithms Genetic algorithms

Search procedures based on the mechanics of natural selection and genetics. Such procedures are known also as evolution strategies, evolutionary programming, genetic programming, and evolutionary computation.
 (ICANNGA ICANNGA International Conference on Artificial Neural Networks and Genetic Algorithms ), a biannual bi·an·nu·al  
adj.
1. Happening twice each year; semiannual.

2. Occurring every two years; biennial.



bi·an
 meeting of the computational optimization community, April 2-4, at Norwich University (Norwich, UK).

Noever is presenting two papers in plenary sessions on Wednesday morning, April 2 and Friday afternoon, April 4. These papers discuss different aspects of parallel optimization for drug discovery and high-throughput identification of lead compounds using computational methods. CCI scientists are using a proprietary drug discovery technology to rapidly identify and improve new drugs.

This year's papers feature work on methods which scale up towards considering many billions of compounds with antibacterial, antifungal and antiviral properties.

"We are pleased to be presenting again at ICANNGA on our latest computational discovery methods," said Andrew Brittain, Ph.D., president of CCI.

"Our work on HIV HIV (Human Immunodeficiency Virus), either of two closely related retroviruses that invade T-helper lymphocytes and are responsible for AIDS. There are two types of HIV: HIV-1 and HIV-2. HIV-1 is responsible for the vast majority of AIDS in the United States.  protease inhibitors Protease Inhibitors Definition

A protease inhibitor is a type of drug that cripples the enzyme protease. An enzyme is a substance that triggers chemical reactions in the body.
 was a prominent feature at the last ICANNGA conference in Montpellier, France in 1995, and we have taken our discovery method into the laboratory for multiple indications since then.

"This year's ICANNGA presentations highlight how the triad of new drug discovery technologies -- combinatorial chemistry, high-throughput screening and computational intelligence -- will demand the best algorithms to select only those compounds with favorable therapeutic profiles.

"We increasingly see next-generation drug discovery as a challenge to those companies lacking computing sophistication so·phis·ti·cate  
v. so·phis·ti·cat·ed, so·phis·ti·cat·ing, so·phis·ti·cates

v.tr.
1. To cause to become less natural, especially to make less naive and more worldly.

2.
 -- otherwise the full potential of a new drug lead will simply be missed by trial-and-error discovery methods."

CCI employs powerful computer methods for identifying active treatments using its in virtuo screening, which takes the traditional in vitro in vitro /in vi·tro/ (in ve´tro) [L.] within a glass; observable in a test tube; in an artificial environment.

in vi·tro
adj.
In an artificial environment outside a living organism.
 and in vivo models of drug discovery into a more highly flexible and scalable technology. The increasing demands of such large sequencing projects as the Human Genome Project makes any new technology appealing only if it can move rapidly from a few hundred to perhaps as many as multibillion numbers of compounds.

Since the computer can pinpoint the essential chemical features underlying potent therapeutics, CCI's methods can address potentially large markets with unmet clinical needs.

CCI is a biopharmaceutical company engaged in the development of computational drug discovery technologies for the rapid and parallel identification, synthesis and testing of therapeutics for infectious diseases.

The company has placed primary emphasis on the accelerated development of its computational in virtuo screening methods for multiple indications. CCI has headquarters in Huntsville, with laboratories at SUNY SUNY - State University of New York  Stonybrook, New York.

CONTACT: CyberChemics Inc., Huntsville

Andrew Brittain, 205/881-8805, fax: 205-881-3372

abritt@ro.com

or

BioScience Ventures, Inc.

David Palella, 619/793-0741, fax: 619-793-0742

palella@palella.com
COPYRIGHT 1997 Business Wire
No portion of this article can be reproduced without the express written permission from the copyright holder.
Copyright 1997, Gale Group. All rights reserved. Gale Group is a Thomson Corporation Company.

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Publication:Business Wire
Date:Apr 1, 1997
Words:434
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