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Cure for nut allergies is 'a step closer'.


SCIENTISTS are one step closer to curing nut allergies following the success of a clinical trial.

Experts gave small daily doses of peanut flour to children with severe peanut allergy peanut allergy Immunology A common cause of anaphylactic reactions which, unlike some allergies, is rarely outgrown; PA is the most common cause of food allergy in the US, and a leading cause of food-induced anaphylaxis and death after accidental exposure  to help build tolerance to the nuts and, by the end of the trial, the children could eat up to 12 nuts a day without suffering a life-threatening reaction in the form of anaphylaxis anaphylaxis (ăn'əfəlăk`sĭs), hypersensitive state that may develop after introduction of a foreign protein or other antigen into the body tissues. .

Although the study was small, the Cambridge-based team said it represents the world's first successful peanut desensitisation n. 1. same as desensitization.

Noun 1. desensitisation - the process of reducing sensitivity; "the patient was desensitized to the allergen"
desensitization

decrease, decrement - a process of becoming smaller or shorter
 programme.

Consultant Andrew Clark, who led the research, said further studies were planned to look at other types of nuts and other foods that seem to fuel an increase in food allergies.

Mr Clark said his team were "definitely" one step closer to finding a cure for food allergies, which he said were on the rise.

In the latest study, published in the journal Allergy, four children were given peanut oral immunotherapy (OIT OIT Organización Internacional del Trabajo (Spanish: International Labor Organization)
OIT Organisation Internationale du Travail (International Labour Organization)
OIT Office of Information Technology
) to help build tolerance to peanut protein.

Mr Clark said: "At the moment we know that if they continue to eat five peanuts a day, their tolerance is maintained.

"If they were to stop, then there is some evidence that tolerance would be lost and they may have a reaction."

Mr Clark said the children would be followed for the next three or four years to monitor their tolerance levels and future studies would assess whether the dose could be given as a daily pill.
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Publication:The Journal (Newcastle, England)
Date:Feb 20, 2009
Words:239
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