CuraGen and Biogen Sign Research Collaboration Agreement.NEW HAVEN New Haven, city (1990 pop. 130,474), New Haven co., S Conn., a port of entry where the Quinnipiac and other small rivers enter Long Island Sound; inc. 1784. Firearms and ammunition, clocks and watches, tools, rubber and paper products, and textiles are among the many , Conn.--(BUSINESS WIRE)--Nov. 10, 1997--CuraGen Corporation, a Connecticut-based biotechnology company, announced today that it has signed a research collaboration agreement with Biogen, Inc. of Cambridge, MA. Under the agreement, CuraGen and Biogen will collaborate in the discovery of novel therapeutics therapeutics Treatment and care to combat disease or alleviate pain or injury. Its tools include drugs, surgery, radiation therapy, mechanical devices, diet, and psychiatry. across a range of disease programs. The companies will also conduct pharmacogenomic analysis of selected products and product candidates in Biogen's portfolio. The collaboration will provide Biogen with access to CuraGen's proprietary genomics platform, including the GeneCalling system for gene expression analysis and gene discovery, the PathCalling system for the discovery of the roles of genes and the proteins they encode (1) To assign a code to represent data, such as a parts code. Contrast with decode. (2) To convert from one format or signal to another. See codec and D/A converter. (3) The term is sometimes erroneously used for "encrypt. in biological pathways, and the GeneScape bioinformatics operating system operating system (OS) Software that controls the operation of a computer, directs the input and output of data, keeps track of files, and controls the processing of computer programs. for web-based project management, data analysis and visualization Using the computer to convert data into picture form. The most basic visualization is that of turning transaction data and summary information into charts and graphs. Visualization is used in computer-aided design (CAD) to render screen images into 3D models that can be viewed from all . This platform will be used to generate GeneCalling and PathCalling databases from Biogen-specified disease systems. Biogen will also gain non-exclusive access to CuraGen's GeneCalling and PathCalling subscription databases. Under the terms of the agreement, Biogen agreed to invest $5 million in CuraGen to purchase CuraGen common stock at its initial public offering price and to provide a $10 million loan facility. At any time during the term of the agreement, the loan is convertible at CuraGen's option into CuraGen common stock at the prevailing market price. Biogen will additionally provide payments over five years to support the research collaboration and to gain non-exclusive access to CuraGen's GeneCalling and PathCalling subscription databases. Biogen has an exclusive right during specified periods to evaluate discoveries arising from the collaboration and to license discoveries upon payment of an additional fee. After the period of exclusivity elapses, rights to genes not licensed to Biogen and rights to the data will revert to CuraGen for inclusion in its subscription databases. Biogen will provide milestone payments up to $18.5 million for each therapeutic product that is developed under an exclusive license and attains certain development and commercialization milestones and will pay royalties based on future product sales. CuraGen Corporation is developing and applying genomics technologies, processes and information systems to accelerate drug discovery, drug development and pharmacogenomics Pharmacogenomics is the branch of pharmacology which deals with the influence of genetic variation on drug response in patients by correlating gene expression or single-nucleotide polymorphisms with a drug's efficacy or toxicity. . CuraGen established operations in 1993, employed 150 people as of September 30, 1997, including 70 employees with doctoral degrees, and has its principal offices in New Haven, Connecticut, with additional research facilities in Branford, Connecticut Branford is a town located on Long Island Sound in New Haven County, Connecticut, eight miles (13 km) east of New Haven. The population was 29,089 in 2005, according to the U.S. Census Bureau. and Alachua, Florida Alachua is a city in Alachua County, Florida, United States. According to 2006 U.S. Census Bureau estimates, the city's population was 7,554.[2] The city is part of the Gainesville, Florida Metropolitan Statistical Area, which is home to 243,985 people. . CuraGen's technology development has been supported in part by the Advanced Technology Program at the National Institute of Standards and Technology National Institute of Standards and Technology, governmental agency within the U.S. Dept. of Commerce with the mission of "working with industry to develop and apply technology, measurements, and standards" in the national interest. and by the National Institutes of Health. CONTACT: CuraGen Gregory T. Went, Ph.D. Executive Vice President gwent@curagen.com 1-888-GENOMICS |
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