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Cultural barriers keep Kenyan and Ugandan women out of AIDS vaccine trials.


The participation by women in HIV/AIDS HIV/AIDS Human Immunodeficiency Virus/Acquired Immune Deficiency Syndrome  vaccine trials A vaccine trial is a clinical trial that aims at establishing the safety and efficacy of a vaccine prior to it being licensed. Methodology
A basic trial might involve forming two groups from a random sample of the target population.
 in Kenya and Uganda has been hampered by cultural inhibitions, scientists in the trials said recently. Trials of a vaccine that promises to provide a solution to HIV HIV (Human Immunodeficiency Virus), either of two closely related retroviruses that invade T-helper lymphocytes and are responsible for AIDS. There are two types of HIV: HIV-1 and HIV-2. HIV-1 is responsible for the vast majority of AIDS in the United States.  and AIDS are currently under way in Kenya and Uganda, but the participation of women has been low. The scientists said that this low participation by women, who are more vulnerable to infection than men, could hinder comprehensive conclusions on the efficacy of the vaccine.

Medical officers say that for comprehensive conclusions to the vaccine trials in both sexes, a substantial number of women have to participate. However, in African culture, a woman has little say about sexual matters in a family. The fact that participation in this trial revolves around the sexual life of a couple makes it difficult for women to become involved in it, said a member of the Community Advisory Board (CAB) in Uganda.

CAB comprises opinion leaders in Kampala and Entebbe where the HIV vaccine HIV vaccine AIDS As of mid-2005, there is no viable anti-HIV vaccine. See AIDS.  trial is taking place. They provide advice on matters related to vaccine recruitment and enrolment at the clinical trial. "We think that their husbands have not allowed them to come back because during the sensitisation Noun 1. sensitisation - the state of being sensitive (as to an antigen)
sensitization

irritation - (pathology) abnormal sensitivity to stimulation; "any food produced irritation of the stomach"
 seminars the turn-out was 50/50 for men and women," said Dr Fred Nakwagala.

Dr Nakwagala added that all four women enrolled for the Uganda trials were single mothers, who would have more freedom in making their own decisions than married women who usually need the consent of their husbands. Moreover, women also had the burden of looking after the home and so might not have enough time to report to the vaccine sites.

Source: The East African Adj. 1. East African - of or relating to or located in East Africa  (Nairobi), 4 August 2003
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Title Annotation:NEWS CLIPPINGS
Publication:Sister Namibia
Article Type:Brief Article
Geographic Code:6UGAN
Date:Nov 1, 2003
Words:284
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