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Covalon Receives U.S.A. Patent And European Patent Certificate For Anti-Microbial Coating Technology Applied To Implantable Medical Devices.


MISSISSAUGA, Ontario -- Covalon Technologies Ltd. (TSX TSX Toronto Stock Exchange (TSE before April, 2002)
TSX Transfer from Stack Pointer to Index
TSX True Space Extension
 VENTURE:COV COV Composés Organiques Volatiles (French)
COV Compuestos Orgánicos Volátiles (Spanish: Volatile Organic Compounds)
COV Coefficient of Variation
COV City of Villians (game) 
) is extremely pleased to announce that it has received a U.S.A. patent and a European Patent Certificate for its method of making silver ion-releasing anti-microbial coatings for implantable medical devices for reducing hospital acquired infections in patients.

Covalon has received U.S.A. and European patent protection for its technology in applying an anti-microbial, sustained silver ion-releasing coating/complex to wound dressings, skin surface coverings and implantable medical devices for deterring the onset of hospital acquired infections (HAI) in patients. The use of skin coverings and implanted medical devices are a vital component of clinical practice, however, complications may arise from their use. Complications include the potential of the device to become the focus of microbial microbial

pertaining to or emanating from a microbe.


microbial digestion
the breakdown of organic material, especially feedstuffs, by microbial organisms.
 contamination that may lead to an HAI in the patient.

In the U.S.A., 2 million hospital patients contract infections; over 100,000 deaths per year are a result of HAI. The toll from HAI is higher than that from AIDs and automobile accidents combined. More specifically, urinary tract infections (UTIs) account for 40% of HAI and 15-50% of hospitalized patients with a urinary catheter experience a UTI UTI urinary tract infection.

UTI
abbr.
urinary tract infection



UTI

urinary tract infection.

UTI Urinary tract infection, see there
 from the catheterization catheterization

Threading of a flexible tube (catheter) through a channel in the body to inject drugs or a contrast medium, measure and record flow and pressures, inspect structures, take samples, diagnose disorders, or clear blockages.
. The added cost to American hospitals in order to combat UTIs is about US$1.8 Billion per year.

Dr. Frank DiCosmo, Covalon's CEO (1) (Chief Executive Officer) The highest individual in command of an organization. Typically the president of the company, the CEO reports to the Chairman of the Board.  said, in response to the serious and growing problem of HAI, Covalon has developed an anti-microbial silver ion-releasing coating that can be applied to many medical devices to help reduce the incidence of HAI associated with the use of the devices. The anti-microbial sustained silver ion-release coating/complex provides unique opportunities to develop products which are closely tailored to the type of device used, the needs of patients and healthcare providers. Various skin coverings and catheters can take advantage of Covalon's unique coating technology. The clinical devices include: wound dressings, I.V. lines, endotracheal tubes, dialysis lines, urinary catheters, as well as many others devices. The devices modified with Covalon's coating are provided with a low-friction, anti-microbial coating in which silver ion is presented as a broad spectrum anti-microbial agent that is effective against Methicillin-resistant Staphylococcus aureus methicillin-resistant Staphylococcus aureus Methicillin-aminoglycoside resistant Staphylococcus aureus, MRSA An organism with multiple antibiotic resistances–eg, aminoglycosides, chloramphenicol, clindamycin, erythromycin, rifampin, tetracycline,  (MRSA MRSA Methicillin-resistant Staphylococcus aureus. See MARSA. ), Vancomycyin-resistant Enterococcus enterococcus /en·tero·coc·cus/ (en?ter-o-kok´us) pl. enterococ´ci   an organism belonging to the genus Enterococcus.
Enterococcus /En·tero·coc·cus/ (
 (VRE VRE

vancomycin-resistant enterococcus.

VRE Vancomycin-resistent enterococcus, see there
), other gram-positive and gram-negative bacteria, and yeasts. Covalon is very pleased that the technology is applicable to a wide variety of medical devices that can benefit from sustained release of anti-microbial silver ion that may help reduce the incidence of HAI and improve patient outcome.

Covalon Technologies Ltd., is an advanced medical biosystems company that has developed and patented advanced therapeutic biomaterials for wound care and surgical applications and coatings. Polymer chemistry and surface coating technology have been combined to create a range of time-release drug delivery platforms that are applied to many medical devices to treat many critical conditions. A variety of applications for these technologies have been identified and specific products have been developed. The products offer features and benefits providing solutions to many of the problems caused by current devices and their material properties which are used by most medical device manufacturers and suppliers. The problems include infection, poor biocompatibility biocompatibility

the quality of not having toxic or injurious effects on biological systems.

biocompatibility 1. The extent to which a foreign, usually implanted, material elicits an immune or other response in a recipient 2.
, and microbial attachment.

The TSX Venture Exchange TSX Venture Exchange

Originally called the Canadian Venture Exchange (CDNX), this was a result of the merger of the Vancouver and Alberta stock exchanges. The goal of TSX Venture Exchange is to provide venture companies with effective access to capital while protecting investors.
 has not reviewed and does not accept responsibility for the adequacy or accuracy of this release. The TSX Venture Exchange has in no way passed upon the merits of the proposed transaction and has neither approved nor disapproved of the contents of this release.

This document contains forward-looking statements. These statements relate to future performance. In some cases, forward-looking statements can be identified by terminology such as "may", "will", "should", "expect", "plan", "anticipate", "believe", "estimate", "predict", "potential", "continue", or the negative of any of these terms or comparable terminology. Such statements reflect the current views of management of the Company with respect to future events. Actual events or results may differ materially. Given these uncertainties, readers are cautioned not to place undue reliance on such forward-looking statements. The Company disclaims any obligation to update any such factors or to publicly announce the result of any revisions to any of the forward -looking statements contained herein to reflect future results, events or developments.

Covalon Technologies Ltd. (TSX VENTURE:COV)
COPYRIGHT 2005 Business Wire
No portion of this article can be reproduced without the express written permission from the copyright holder.
Copyright 2005, Gale Group. All rights reserved. Gale Group is a Thomson Corporation Company.

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Publication:Business Wire
Date:Apr 20, 2005
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