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Cortecs International discusses fiscal 1994 accomplishments, 1995 objectives at annual general meeting.


LONDON--(BUSINESS WIRE)--Nov. 16, 1994--At its Annual General Meeting held in London yesterday, shareholders of Cortecs International (NASDAQ NASDAQ
 in full National Association of Securities Dealers Automated Quotations

U.S. market for over-the-counter securities. Established in 1971 by the National Association of Securities Dealers (NASD), NASDAQ is an automated quotation system that reports on
: DLVRY/ASX: CRI CRI

constant-rate infusion.
) reelected to the board of directors Glen Travers, Cortecs' executive chairman, Dr. Michael Flynn, the company's president, and Dr. Dudley Earl.

During the meeting, Travers reviewed with shareholders the company's accomplishments during the 1994 fiscal year ended June 30, 1994 citing in particular:

o The full listing and admission of Cortecs to trading on the London Stock Exchange London Stock Exchange

London marketplace for securities. It was formed in 1773 by a group of stockbrokers who had been doing business informally in local coffeehouses.
;

o The raising of UK$15 million in equity through a private placing of new ordinary shares with current major shareholders and other institutions. Together with the company's existing resources, it is expected funding is in place for at least the next two years;

o Revenues from pharmaceutical marketing and diagnostics operating divisions (of UK$4.7 million), which helped offset ongoing research and development costs in the company's core oral drug delivery business, will reduce the company's capital "burn rate" and extend the funding time horizon;

o The launching of the company's first Rapid Point of Care Diagnostic, Helisal Rapid Blood, for the detection of helicobacter pylori Helicobacter pylori
A gramnegative rod-shaped bacterium that lives in the tissues of the stomach and causes inflammation of the stomach lining.

Mentioned in: Indigestion, Ulcers

Helicobacter pylori
, a common cause of peptic ulcers Peptic ulcers
Wounds in the stomach and duodenum caused by stomach acid and the bacterium Helicobacter pylori.

Mentioned in: Tube Compression of the Esophagus and Stomach
 and gastritis gastritis

Inflammation in the stomach. Acute gastritis, usually caused by ingesting something irritating or by infection, starts suddenly, with severe pain, vomiting, thirst, and diarrhea, and subsides rapidly.
;

o The signing of several collaboration agreements covering Helisal-based H. pylori products, including Boehringer Mannheim Diagnostics, Sweden-based Astra and Zenyaku Kogyo, a Tokyo-based pharmaceutical company;

o The signing of a testing agreement with Hoechst Veterinar GmbH for the company's ant-diarrheal project, ADEPT.

o Entering into Phase II clinical trials in the U.K. for the oral delivery of salmon calcitonin calcitonin /cal·ci·to·nin/ (-to´nin) a polypeptide hormone secreted by C cells of the thyroid gland, and sometimes of the thymus and parathyroids, which lowers calcium and phosphate concentration in plasma and inhibits bone resorption.  for the treatment of post-menopausal osteoporosis and Paget's disease Paget's disease
n.
1. A disease, occurring chiefly in old age, in which the bones become enlarged and weakened, often resulting in fracture or deformation. Also called osteitis deformans.

2.
;

o The completion of a Phase I study with the pseudomonas aeruginosa Pseudomonas aeruginosa A normal soil inhabitant and human saprophyte that may contaminate various solutions in a hospital, causing opportunistic infection in weakened Pts Clinical Infective endocarditis in IVDAs, RTIs, UTIs, bacteremia, meningitis, 'malignant'  vaccine for cystic fibrosis cystic fibrosis (sĭs`tĭk fībrō`sĭs), inherited disorder of the exocrine glands (see gland), affecting children and young people; median survival is 25 years in females and 30 years in males. ;

o The commencement of Phase I studies for the oral delivery of insulin;

Separately, the company announced that it has applied for patent applications for its MACROSOL oral delivery technology (derived from the company's MACROMOL technology). Developed in London, the technology brings together its oral delivery of large molecule peptides and proteins systems applying them to the wide field of vaccination. Initial animal tests have been completed with encouraging results; further detailed tests are currently underway with results expected in early 1995.

The company also announced the appointment of Dr. Leonard Brookes as Director of Research and Development. Brookes will oversee the company's initiative from the research phase of its oral drug delivery technologies into the production phase.

Added Travers: "We are optimistic about developments of MACROMOL in the oral delivery of biotechnology drugs and anticipate results from our new technology for oral prevention and treatment of a broad range of local and systemic infections. We believe that these technologies could provide tremendous commercial opportunities for Cortecs.

"In conclusion, the past year has been one of positive achievement in which we have negotiated agreements with major international pharmaceutical companies. We have progressed our key R & D projects, brought the total to nearly one hundred and fifty peer reviewed publications and had additional patents granted and applied for. We have also launched product in the form of the Helisal range, particularly the rapid tests, and are looking forward to increased revenues from our diagnostics division as our UK and overseas sales start to build."

Cortecs is a British-based company quoted on the London Stock Exchange, the Australian Stock Exchange Australian Stock Exchange (ASX)

Australia's major securities market, formed when the six state stock exchanges (Adelaide, Brisbane, Hobart, Melbourne, Perth, and Sydney stock exchanges) were merged in 1987.
, and on NASDAQ. The company specializes in the development of new pharmaceutical delivery systems for the healthcare industry. Cortecs currently has several innovative drug delivery technologies under development.

CONTACT: Cortecs International Ltd., London
             Michael Flynn, 011-44-81-568-7071
                    or
             Kehoe, White, Savage & Co. Inc., New York
             John P. Kehoe/Robert Cavosi, 212/888-1616
COPYRIGHT 1994 Business Wire
No portion of this article can be reproduced without the express written permission from the copyright holder.
Copyright 1994, Gale Group. All rights reserved. Gale Group is a Thomson Corporation Company.

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Publication:Business Wire
Date:Nov 16, 1994
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