Corporate Profile for Maxim Pharmaceuticals, dated Oct. 11, 2002.Business Editors --(BUSINESS WIRE) The following Corporate Profile is available for inclusion in your files. News releases for this client are distributed by Business Wire and also become part of the leading databases and online services, including all of the leading Internet-based services.
Published Date: Oct. 11, 2002
Company Name: Maxim Pharmaceuticals
Address: 8899 University Center Lane
San Diego, Calif. 92122
Main Telephone
Number: 858/453-4040
Internet Home
Page Address
(URL) www.maxim.com
Chief Executive
Officer: Larry G. Stambaugh
Chief Financial
Officer: Anthony Altig
Industry: Biopharmaceutical
Trading Symbol/
Exchange: MAXM/Nasdaq
Company description: Maxim is a global bio-pharmaceutical company with a diverse pipeline of product candidates for life-threatening cancers and hepatitis. Our innovative technology, strong financial resources and experienced management provide a solid foundation for commercializing multiple products. Maxim's research and development programs promise hope to patients most in need by developing safe and effective product candidates that have the potential to extend survival while maintaining quality of life. Maxim has attracted an experienced international management group and a team of employees dedicated to commercializing life-enhancing product candidates. Joining this motivated team in its mission are world-leading scientific and clinical investigators and major pharmaceutical development partners. THREE TECHNOLOGY PLATFORMS -- LIFE-ENHANCING PRODUCT CANDIDATES Ceplene Maxim's lead drug candidate Ceplene (histamine histamine (hĭs`təmēn'), organic compound derived in the body from the amino acid histidine by the removal of a carboxyl group (COOH). dihydrochloride), based on the naturally occurring molecule histamine, prevents production and release of oxygen free radicals, thereby reducing oxidative stress oxidative stress, n an imbalance of the prooxidant antioxidant ratio in which too few antioxidants are produced or ingested or too many oxidizing agents are produced. , a process implicated im·pli·cate tr.v. im·pli·cat·ed, im·pli·cat·ing, im·pli·cates 1. To involve or connect intimately or incriminatingly: evidence that implicates others in the plot. 2. in numerous diseases. Accordingly, treatment with Ceplene has the potential to prevent or reverse damage induced by oxidative stress, thereby protecting critical cells and tissue, including immune cells. Ceplene is Maxim's most advanced platform targeting life-threatening cancers and hepatitis C Hepatitis C Definition Hepatitis C is a form of liver inflammation that causes primarily a long-lasting (chronic) disease. Acute (newly developed) hepatitis C is rarely observed as the early disease is generally quite mild. . An extensive series of Phase 3, 2 and 1 clinical trials have been completed with more than 1,400 patients tested. Clinical development currently underway includes: -- Phase 3 trials in advanced metastatic melanoma, the most deadly form of skin cancer -- Phase 3 trial in acute myelogenous leukemia, the most common acute adult leukemia -- Phase 2 trials in advanced renal cell carcinoma (cancer of the kidneys) -- Phase 2 trials in hepatitis C, one of the world's most common blood-borne viruses Apoptosis Modulators Maxim is also developing small-molecule inhibitors and activators of programmed cell death pro·grammed cell death n. See apoptosis. programmed cell death proposed system of cell death, often including poly(ADP)-ribosylation, ensures that a cell will not survive if it is so badly damaged that its recovery would harm the , also known as apoptosis, that may serve as drug candidates for cancer, cardiovascular disease Cardiovascular disease Disease that affects the heart and blood vessels. Mentioned in: Lipoproteins Test cardiovascular disease and other degenerative diseases. -- Apoptosis Inducers: Anti-cancer product candidates -- Apoptosis Inhibitors: Product candidates for cardiovascular disease and other degenerative diseases These product candidates were identified using Maxim's proprietary, high-throughput, live-cell screening technology. Topical Therapies The company has also developed product candidates based on its topical histamine gel technology that are designed for the treatment of medical conditions See carpal tunnel syndrome, computer vision syndrome, dry eyes and deep vein thrombosis. for which topical therapy is appropriate such as oral mucositis, herpes, decubitus ulcers Decubitus ulcers A pressure sore resulting from ulceration of the skin occurring in persons confined to bed for long periods of time Mentioned in: Immobilization , shingles shingles: see herpes zoster. shingles or herpes zoster Acute viral skin and nerve infection. Groups of small blisters appear along certain nerve segments, most often on the back, sometimes after a dull ache at the site; pain becomes , burns and related conditions. Maxim has commenced pilot human studies in: -- Oral mucositis -- Radiation dermatitis radiation dermatitis n. See radiodermatitis. |
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