Cooke Pharma's HeartBar First Medical Food for Heart and Vascular Disease, Applies Nobel Prize Science to Cardiovascular Health.BELMONT, Calif.--(BW HealthWire)--Oct. 22, 1998--After more than a decade of research, Cooke Pharma, a San Francisco Peninsula The San Francisco Peninsula in California separates the San Francisco Bay from the Pacific Ocean. On its northern tip is the city of San Francisco. On its southern end is part of Santa Clara County, including the cities of Palo Alto, Los Altos, and Mountain View. company, announced today that it will soon introduce HeartBar, the first medical food developed for the dietary management of coronary artery coronary artery n. 1. An artery with origin in the right aortic sinus; with distribution to the right side of the heart in the coronary sulcus, and with branches to the right atrium and ventricle, including the atrioventricular branches and and vascular disease. This product uses the same mechanism of action that was recently awarded the 1998 Nobel Prize Nobel Prize, award given for outstanding achievement in physics, chemistry, physiology or medicine, peace, or literature. The awards were established by the will of Alfred Nobel, who left a fund to provide annual prizes in the five areas listed above. for Medicine. "The discovery of Drs. Furchgott, Murad, and Ignarro that blood vessels Blood vessels Tubular channels for blood transport, of which there are three principal types: arteries, capillaries, and veins. Only the larger arteries and veins in the body bear distinct names. make nitric oxide nitric oxide or nitrogen monoxide, a colorless gas formed by the combustion of nitrogen and oxygen as given by the reaction: energy + N2 + O2 → 2NO; m.p. −163.6°C;; b.p. −151.8°C;. has tremendous implications for cardiovascular health. In my lab at Stanford we found that nitric oxide acts as our self-defense mechanism against `hardening of the arteries hardening of the arteries: see arteriosclerosis. ,' the major cause of heart attack and stroke," said Dr. John Cooke, founder of Cooke Pharma and Associate Professor of Medicine and Director of the Section of Vascular Medicine at Stanford University. "Cooke Pharma was founded to make this science available to people with coronary artery and vascular disease in a good tasting and convenient food product. We developed HeartBar, the first arginine-enriched medical food, that enhances the body's production of nitric oxide. By boosting nitric oxide production, HeartBar significantly increases blood flow and pain free exercise. I am pleased that the science behind HeartBar has been awarded the 1998 Nobel Prize in Medicine," said Darlene Walley, Ph.D., President of Cooke Pharma. Endothelial endothelial /en·do·the·li·al/ (-the´le-al) pertaining to or made up of endothelium. Endothelial A layer of cells that lines the inside of certain body cavities, for example, blood vessels. nitric oxide production is reduced in people with coronary artery and vascular disease, high cholesterol Cholesterol, High Definition Cholesterol is a fatty substance found in animal tissue and is an important component to the human body. It is manufactured in the liver and carried throughout the body in the bloodstream. , diabetes, hypertension, estrogen deficiency, or tobacco exposure. On Oct. 12, 1998, Sweden's Karolinska Institute awarded the Nobel Prize for Medicine to Americans Robert Furchgott, Ferid Murad and Louis Ignarro for their discoveries about nitric oxide as a signaling molecule in the cardiovascular system. Nitric oxide is a gas that transmits signals in the organism, allowing messages to be sent from one part of the body to another, and regulates blood pressure and blood flow. In sum, nitric oxide tells blood vessels to relax and widen. Dilated dilated a state of dilatation. dilated cardiomyopathy see congestive cardiomyopathy. dilated pupil syndrome see feline dysautonomia (Key-Gaskell syndrome). vessels can carry more blood to oxygen-starved tissues. "Signal transmission by a gas that is produced by one cell, penetrates through membranes and regulates the function of another cell, represents an entirely new principle for signaling in biological systems...We know today that nitric oxide acts as a signal molecule in the nervous system, as a weapon against infections, as a regulator of blood pressure, and as a gatekeeper of blood flow to different organs," the Institute said in its award citation. Cooke Pharma, founded in 1995, is a leader in the development and marketing of innovative cardiovascular nutritional products. Its primary goal is to develop, to scientifically validate, and to bring to market new therapeutic formulations of nutrients that enhance cardiovascular health. For more information contact Darlene Walley, President, at 650/594-5961, ext. 21 or contact Cooke Pharma at www.cookepharma.com. |
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