Controversies in ototopical therapy: highlights of a roundtable discussion sponsored by Alcon Laboratories, Inc.; March 18-20, 2005; Bariloche, Argentina.

Contents

Participants

Introduction

Definitions of otologic diseases and recommended study designs
Introduction
Definitions
Definition of acute otitis media (AOM)
Definition of otitis media with effusion (OME)
Definition of AOM through tympanostomy tubes (AOMT)
Definition of chronic suppurative otitis media (CSOM)
Methodology of AOM studies

Ecologic impact of broad-spectrum quinolones

Introduction
Antibiotic prescribing patterns
Quinolone pharmacology
Normal ecology in the healthy patient
Isolates in chronic ear disease
Mechanism of quinolone resistance
Trends in antibiotic resistance
Preventing resistance
Fungal infections

Safety and efficacy of topical quinolones

Introduction
Ototoxicity
No evidence of quinolone ototoxicity
Chronic suppurative otitis media

Safety and efficacy of topical steroids with and without topical
antibiotics

Introduction
Pharmacokinetics of steroids
Safety of steroids
Beneficial effects of steroids
Combined effects of steroids and antibiotics

Participants

Joseph E. Dohar, MD, MS, FAAP, FACS

Roundtable Chairman

Dr. Dohar is an associate professor ofotolaryngology at the University of Pittsburgh School of Medicine and a pediatric otolaryngologist at the Children's Hospital of Pittsburgh. He is also a member faculty of the University of Pittsburgh McGowan Institute for Regenerative Medicine and clinical director of the Division of Voice, Resonance, and Swallowing and research director of the Aerodigestive Disorders Center at the Children's Hospital of Pittsburgh.

Patrick J. Antonelli, MD, MS, FACS

Dr. Antonelli is a professor and chairman of the Department of Otolaryngology-Head and Neck Surgery at the University of Florida College of Medicine in Gainesville.

Harvey Coates, AO, MS, FRACS

Dr. Coates is a clinical associate professor in the Department of Otolaryngology at the University of Western Australia in Perth. He specializes in pediatric otolaryngology and has a particular interest in his country's Aboriginal children.

Thomas Deitmer, MD, PhD

Prof. Deitmer is head of the Department of Otolaryngology at Klinikum Dortmund, Teaching Hospital of the University of MUnster. Like most otolaryngologists in Germany, he is a generalist.

Ann Edmunds, MD

Dr. Edmunds is an otolaryngologist in private practice in Omaha, Neb. She is affiliated with Boys Town National Research Hospital and is on the clinical faculty at Creighton University Medical Center.

Billy Giles, MD

Dr. Giles is a pediatric otolaryngologist in private practice in Columbia, S.C. He is also affiliated with the Department of Pediatrics and the Department of Surgery at the University of South Carolina.

Michael Hawke, MD

Prof. Hawke is with the Department of Otolaryngology at the University of Toronto. His research interests include ear disease, ototoxicity, sleep disorders, sinus disease, and medical photography. His collection of medical images is available at www.hawkelibrary.com.

Scott Manning, MD

Dr. Manning is a professor of otolaryngology at the University of Washington and chief of pediatric otolaryngology at Children's Hospital and Regional Medical Center in Seattle. His research interests include sinusitis, otitis media, and pediatric airway problems.

Therese Ovesen, MD, PhD

Prof. Ovesen is head of research in the Department of Oto-Rhino-Laryngology at Aarhus University Hospital in Aarhus, Denmark.

John Rutka, MD, FRCSC

Dr. Rutka is a staff neurotologist and an associate professor in the Department of Otolaryngology at the University of Toronto. He is also director of the Ear Pathology Research Laboratory and codirector of the University Health Network (UHN) Centre for Advanced Hearing and Balance Testing and the UHN Multidisciplinary Neurotology Clinic.

Zorik Spektor, MD, FAAP

Dr. Spektor is a pediatric otolaryngologist in West Palm Beach, Fla. He is also director of the Center for Pediatric ENT-Head and Neck Surgery and a member of the clinical faculty in the Department of Otolaryngology at the University of Miami. His areas of interest are chronic otitis media, sinus disease, and airway reconstruction.

David Stroman, PhD

Dr. Stroman is director of antiinfective microbiology at Alcon Laboratories in Fort Worth, Tex.

Ramzi T. Younis, MD

Dr. Younis is chief of the Division of Pediatric Otolaryngology-Head and Neck Surgery at the University of Miami School of Medicine.