Printer Friendly

Controlled trial of Myers cocktail for fibromyalgia.

Thirty-four adults with fibromyalgia were randomly assigned to receive, in double-blind fashion, weekly intravenous infusions of vitamins and minerals or placebo (Lactated Ringer's solution) for eight weeks. The infusions contained 5 ml of 20% magnesium chloride hexahydrate, 3 ml of 10% calcium gluconate, 1000 mcg of hydroxocobalamin, 100 mg of pyridoxine, 250 mg of dexpanthenol, 1 mg of B complex 100, 2.5 g of vitamin C, and 20 ml of sterile water, and were infused by slow push (10 minutes). Clinically significant improvements were seen in the tender point index, Fibromyalgia Impact Questionnaire, and Beck Depression Inventory compared with baseline. Because of a high placebo response, the improvements in the active-treatment group were only slightly and nonsignificantly greater than the improvements in the placebo group. The treatment effects of intravenous nutrients persisted at four weeks postintervention for tender points, pain, and quality of life, while placebo effects persisted only for tender points.

[ILLUSTRATION OMITTED]

Comment: The Myers cocktail is a popular treatment for fibromyalgia, and anecdotal reports indicate that it is highly beneficial (see Gaby AR. Intravenous nutrient therapy: the "Myers' cocktail." Altern Med Rev. 2002;7:389-403). This is the first controlled trial to evaluate the Myers cocktail as a treatment for fibromyalgia. While substantial improvements were seen, active treatment was only nonsignificantiy more effective than placebo, because there was a very strong placebo response. Of note, however, is the improvement in the active-treatment group persisted after treatment was discontinued, whereas most of the benefit wore off after placebo treatment was discontinued. That finding suggests that the Myers cocktail does have a beneficial effect. Placebo responses typically last no longer than three months. It would therefore be worthwhile to conduct a repeat study of longer duration.

Ali A et al. Intravenous micronutrient therapy (Myers' cocktail) for fibromyalgia: a placebocontrolled pilot study. / Altern Complement Med. 2009;15:247-257.

by Alan R. Gaby, MD

drgaby@earthlink.net
COPYRIGHT 2009 The Townsend Letter Group
No portion of this article can be reproduced without the express written permission from the copyright holder.
Copyright 2009 Gale, Cengage Learning. All rights reserved.

 Reader Opinion

Title:

Comment:



 

Article Details
Printer friendly Cite/link Email Feedback
Title Annotation:Literature Review & Commentary
Author:Gaby, Alan R.
Publication:Townsend Letter
Article Type:Report
Geographic Code:1USA
Date:Nov 1, 2009
Words:317
Previous Article:Book answers questions on wireless radiation.
Next Article:Vitamin K prevents coronary artery calcification.
Topics:


Related Articles
Integrative therapy for fibromyalgia: possible strategies for an individualized treatment program.
Use multidisciplinary approach in fibromyalgia.
Fibromyalgia and intravenous micronutrient therapy (Myers' cocktail).
Cranial electrotherapy stimulation as a proven effective treatment for fibromyalgia.
Try tailored psychotherapy for fibromyalgia.
Hydrotherapy improves pain, knee strength, and quality of life in women with fibromyalgia.
Exercise training and pyridostigmine each have unique benefits for patients with fibromyalgia.

Terms of use | Copyright © 2015 Farlex, Inc. | Feedback | For webmasters