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Contributing to the Fight against Diabetes is Only a Click Away During American Diabetes Month.


Click4Diabetes.com Makes Giving Easy - and Free!

BRISTOL, Tenn. & MENLO PARK, Calif. -- More than 20 million Americans suffer from diabetes, a serious, chronic illness. Now, during American Diabetes Month, everyone has an opportunity to make an impact in the fight against the disease, at no cost, with just a click of the mouse. For each visitor who clicks at www.Click4Diabetes.com, a donation will be made to the American Diabetes Association The American Diabetes Association, or the ADA, is an American health organization providing diabetes research, information and advocacy. Founded in 1940, the American Diabetes Association conducts programs in all 50 states and the District of Columbia, reaching hundreds of  (ADA Ada, city, United States
Ada (ā`ə), city (1990 pop. 15,820), seat of Pontotoc co., S central Okla.; inc. 1904. It is a large cattle market and the center of a rich oil and ranch area.
), the nation's leading nonprofit health organization providing diabetes research, information and advocacy.

Click4Diabetes is sponsored by King Pharmaceuticals, Inc. and Depomed, Inc. The companies launched Click4Diabetes with a $25,000 donation to the ADA and will contribute an additional $4 for each visitor who clicks at the Web site throughout the month of November, up to a total amount of $100,000.

"With 1 in 14 people living with diabetes in this country and more than twenty percent of Americans at risk of developing the disease, education, awareness and research are more important than ever," said Brian A. Markison, President and Chief Executive Officer of King Pharmaceuticals. "We hope through the Click4Diabetes initiative to contribute to the ADA's efforts to improve the lives of people living with this disease."

John W. Fara, Ph.D., Chairman, President and Chief Executive Officer of Depomed added, "Nearly everyone knows someone affected by diabetes, and we're pleased that we are able to provide an opportunity for people to make a contribution during American Diabetes Month that can help turn the tide against this disease."

The incidence of diabetes is increasing by approximately 1 million new cases each year in the United States alone. Approximately 90 percent to 95 percent of people with diabetes suffer from type 2 diabetes type 2 diabetes
n.
See diabetes mellitus.
, the most common metabolic disease metabolic disease,
n a disorder that causes dysfunction of the metabolic action of the body, resulting in loss of control of homeostasis.

paraneoplastic syndrome 
 in the world and the fifth deadliest disease in the United States. Diabetes is the leading cause of blindness, end-stage renal disease End-stage renal disease (ESRD)
Total kidney failure; chronic kidney failure is diagnosed as ESRD when kidney function falls to 5-10% of capacity.

Mentioned in: Chronic Kidney Failure

end-stage renal disease 
, and nontraumatic loss of limb. It can also lead to heart disease, stroke, high blood pressure, kidney disease Kidney Disease Definition

Kidney disease is a general term for any damage that reduces the functioning of the kidney. Kidney disease is also called renal disease.
, and other serious conditions. In the United States, the public health cost of diabetes is more than $130 billion per year.

King Pharmaceuticals and Depomed market Glumetza[TM] (metformin hydrochloride metformin hydrochloride Warning - High-alert drug!

Apo-Metformin (CA), Fortamet, Glucophage, Glucophage XR, Glycon (CA), Metsol (UK), Novo-Metformin (CA), Riomet

Pharmacologic class:
 extended release tablets), a new once-daily extended-release metformin metformin /met·for·min/ (met-for´min) an antihyperglycemic agent that potentiates the action of insulin, used in the treatment of type 2 diabetes mellitus.

met·for·min
n.
 formulation that features AcuForm[TM] drug-delivery technology, for the treatment of adults with type 2 diabetes in the United States.

The Click4Diabetes initiative is sponsored by King Pharmaceuticals, Inc. and Depomed, Inc. The American Diabetes Association is not affiliated with this program and does not endorse any specific diabetes treatment.

To make a donation to the ADA, visit www.click4diabetes.com. For more information about diabetes, visit the ADA's Web site at www.diabetes.org.

About Glumetza

Glumetza[TM] (metformin hydrochloride extended-release tablets) is indicated alone or in combination with sulfonylurea sulfonylurea /sul·fo·nyl·urea/ (sul?fo-nil-u-re´ah) any of a class of compounds that exert hypoglycemic activity by stimulating the islet tissue to secrete insulin; used to control hyperglycemia in patients with type 2 diabetes mellitus  or insulin as an adjunct to diet and exercise to improve glycemic Glycemic
The presence of glucose in the blood.

Mentioned in: Cholesterol, High


glycemic

pertaining to the level of glucose in the blood.
 control in adult patients (18 years and older) with type 2 diabetes. Glumetza[TM] may be used concomitantly with a sulfonylurea or insulin to improve glycemic control in adults.

Glumetza[TM] is contraindicated in patients with renal disease or renal dysfunction (e.g., as suggested by serum creatinine levels greater than or equal to 1.5 mg/dL in males and greater than or equal to 1.4 mg/dL in females), known hypersensitivity hypersensitivity, heightened response in a body tissue to an antigen or foreign substance. The body normally responds to an antigen by producing specific antibodies against it. The antibodies impart immunity for any later exposure to that antigen.  to metformin HCl, and acute or chronic metabolic acidosis, including diabetic ketoacidosis with or without coma. As with all metformins, there is a warning regarding lactic acidosis with Glumetza[TM] due to metformin accumulation during treatment. Lactic acidosis is a rare but potentially fatal occurrence. It may also occur in association with a number of pathophysiologic conditions. The risk of lactic acidosis increases with the degree of renal dysfunction and the patient's age, especially patients eN80 years of age. In clinical trials of Glumetza combined with a sulfonylurea, the most common side effects included hypoglycemia hypoglycemia: see diabetes.
hypoglycemia

Below-normal levels of blood glucose, quickly reversed by administration of oral or intravenous glucose. Even brief episodes can produce severe brain dysfunction.
, diarrhea, and nausea. For additional information on the product, please access the package insert at http://www.depomedinc.com/glumetza_Prescribing_Info.pdf

About King Pharmaceuticals

King (NYSE NYSE

See: New York Stock Exchange
: KG), headquartered in Bristol, Tennessee, is a vertically integrated branded pharmaceutical company. King, an S&P 500 Index company, seeks to capitalize on opportunities in the pharmaceutical industry through the development, including through in-licensing arrangements and acquisitions, of novel branded prescription pharmaceutical products in attractive markets and the strategic acquisition of branded products that can benefit from focused promotion and marketing and product life-cycle management. For more information, visit www.kingpharm.com.

About Depomed, Inc.

Depomed, Inc. is a specialty pharmaceutical company utilizing its innovative AcuForm[TM] drug delivery technology to develop novel oral products and improved, extended release formulations of existing oral drugs. AcuForm-based products are designed to provide once daily administration and reduced side effects, improving patient convenience, compliance and pharmacokinetic profiles. ProQuin[R] XR (ciprofloxacin hydrochloride) extended-release tablets have been approved by the FDA FDA
abbr.
Food and Drug Administration


FDA,
n.pr See Food and Drug Administration.

FDA,
n.pr the abbreviation for the Food and Drug Administration.
 for the once daily treatment of uncomplicated urinary tract infections and are currently being marketed in the United States. In addition, once daily Glumetza[TM] (metformin hydrochloride extended release tablets) has been approved for use in adults with type 2 diabetes and is currently being marketed in the United States and Canada. The company is conducting a Phase III trial in postherpetic neuralgia and a Phase II trial in diabetic peripheral neuropathy Diabetic peripheral neuropathy
A condition where the sensitivity of nerves to pain, temperature, and pressure is dulled, particularly in the legs and feet.

Mentioned in: Diabetes Mellitus
 with its product candidate, Gabapentin GR[TM]. Additional information about Depomed may be found at its web site, www.depomedinc.com
COPYRIGHT 2006 Business Wire
No portion of this article can be reproduced without the express written permission from the copyright holder.
Copyright 2006, Gale Group. All rights reserved. Gale Group is a Thomson Corporation Company.

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Publication:Business Wire
Date:Nov 15, 2006
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