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ConsumerLab points out irony of heparin contamination with chondroitin; calls for better testing.


Dr. William Obermeyer, Vice President for Research at ConsumerLab.com, provides the following insights and commentary on the adulteration Mixing something impure with something genuine, or an inferior article with a superior one of the same kind.

Adulteration usually refers to mixing other matter of an inferior and sometimes harmful quality with food or drink intended to be sold.
 of heparin: "It is ironic that a form of chondroitin sulfate has been implicated in the adulteration of heparin products. Although chondroitin chondroitin (kn·droiˑ·tin),
n
 is less than one-quarter the cost of heparin, it is one of the more expensive dietary supplement ingredients. Less than a year ago, we reported that some chondroitin supplements were, themselves, adulterated with look-alike compounds that could trick nonspecific tests. This was most likely done to cut costs." (News release at https://www.consumerlab.com/news/news_041107_jointuspplements.asp.)

Dr. Obermeyer added, "To avoid being tricked by look-alike compounds, ConsumerLab.com utilizes an enzymatic HPLC HPLC high-performance liquid chromatography.

HPLC

high performance liquid chromatography.

HPLC High-performance liquid chromatography Lab instrumentation A highly sensitive analytic method in which analytes are placed
 method that distinguishes chondroitin from similar sulfated compounds, known as glycosaminoglycans, such as heparin. This method is even more specific than the standard pharmaceutical method for heparin testing. Whether it is [for] supplements or pharmaceuticals, it is clear that more specific tests should be used to avoid adulteration and contamination."

Dr. William Obermeyer co-founded ConsumerLab.com in 1999, coming from the US Food and Drug Administration where he was a Natural Products Chemist, guiding research into various natural products and educating the public, academia, and industry on the safety and proper manufacture and testing of dietary supplements. Dr. Obermeyer is an internationally recognized authority on pharmacognosy pharmacognosy /phar·ma·cog·no·sy/ (fahr?mah-kog´nah-se) the branch of pharmacology dealing with natural drugs and their constituents.

phar·ma·cog·no·sy
n.
 (the science of natural products) and serves on the Executive Board of the AOAC Technical Division for Reference Materials. Dr. Obermeyer received his PhD from the Philadelphia College of Pharmacy and Science. You may contact Dr. Obermeyer directly with questions or requests to arrange an interview at William.Obermeyer@ConsumerLab.com or 410-437-9134.
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Author:Obermeyer, William
Publication:Townsend Letter
Article Type:Brief article
Geographic Code:1USA
Date:Jul 1, 2008
Words:276
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