Consortium starts genome project.
A consortium of research organizations from around the world,
including the National Human Genome Research Institute, is planning to
sequence the genomes of at least 1,000 individuals. The idea, being
called the 1000 Genomes Project, is to create a detailed and clinically
relevant picture of human genetic variation. The data from the project
will be made publicly available at no cost. "This new project will
increase the sensitivity of disease discovery efforts across the genome
fivefold and within gene regions at least 10-fold," Dr. Francis S.
Collins, director of the National Human Genome Research Institute, said
in a statement. "Our existing databases do a reasonably good job of
cataloging variations found in at least 10 percent of a population. By
harnessing the power of new sequencing technologies and novel
computational methods, we hope to give biomedical researchers a
genome-wide map of variation down to the 1 percent level." The
project is being supported by the Wellcome Trust Sanger Institute in
Hinxton, England; the Beijing Genomics Institute; BGI Shenzhen in China;
and the National Human Genome Research Institute, part of the National
Institutes of Health. More information about the project is available
online at www.1000genomes.org.