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Configurability Essential to Overcome Hurdles in Customised Laboratory Automation Devices.


DUBLIN, Ireland -- Research and Markets (http://www.researchandmarkets.com/reports/c48920) has announced the addition of Frost & Sullivan's new report: Advances in Laboratory Automation Markets in Europe to their offering.

This Frost & Sullivan research service titled Advances in Laboratory Automation Markets in Europe provides an analysis on the key drivers, industry challenges, restraints, principal trends and revenue forecasts of different product segments that impact the development of drug discovery. In this research, Frost & Sullivan's expert analysts thoroughly examine the following markets/applications/technologies: automated liquid handling, robotics robotics, science and technology of general purpose, programmable machine systems. Contrary to the popular fiction image of robots as ambulatory machines of human appearance capable of performing almost any task, most robotic systems are anchored to fixed positions  systems, microplate readers and automated compound storage and retrieval sectors.

Market Sectors

Expert Frost & Sullivan analysts thoroughly examine the following market sectors in this research:

- Automated liquid handling

- Robotics systems

- Microplate readers and detection

- Automated compound storage and retrieval

Technologies

The following technologies are covered in this research:

- Bioassay Bioassay

A method for the quantitation of the effects on a biological system by its exposure to a substance, as well as the quantitation of the concentration of a substance by some observable effect on a biological system.
: This refers to the analytical measurement procedure that determines the concentration and the degree of biological activity of the relevant substance.

- Cell-based Assays: Cell-based assays refer to the screening procedure that has the ability to track the behaviour of the dynamic activities inside a cell. With automation becoming imperative, these processes will catalyse catalyse or US -lyze
Verb

[-lysing, -lysed] or -lyzing, -lyzed to influence (a chemical reaction) by catalysis

Verb 1.
 the lead identification process with a faster turn-around-time.

- High Throughput Screening (HTS HTS Heights
HTS Harmonized Tariff System
HTS High Throughput Screening (biomolecular assay screening)
HTS High-Throughput Screening (Pharmaceutical Industry)
HTS Harmonized Tariff Schedule
): HTS is the rapid assessment of sample activity of samples from a combinatorial library combinatorial library

in immunology, the ligation of cDNAs of light and heavy chains of immunoglobulins, each in a separate bacteriophage vector.
 or other compound libraries by running assays in parallel in 96 well or 384 microplates.

- High Content Screening (HCS HCS - Heterogeneous Computer System

A distributed system project.
): HCS is the screening process with multi-dimensional information rich content depicting the spatial and temporal activities of the cell. The enormous advantage that drug research can enjoy would be the availability of functional readouts by cataloguing the cellular activity profiles in every well, thus reporting the cytoxicity, potency potency /po·ten·cy/ (po´ten-se)
1. the ability of the male to perform coitus.

2. the relationship between the therapeutic effect of a drug and the dose necessary to achieve that effect.

3.
 for a compound's behaviour against the target.

Market Overview

Integration of Technologies to Offer Improvements in Laboratory Automation

In recent times, drug discovery design has undergone a revolutionary process due to influential factors such as cost benefits and error reduction, thereby leading to the mandatory requirement for automation in every research laboratory. The emergence of robotics and automated liquid handling requirements is expected to support the use of innovative laboratory automation technology, with enhanced focus on miniaturisation n. 1. miniaturization.

Noun 1. miniaturisation - act of making on a greatly reduced scale
miniaturization

shrinking - the act of becoming less
. Further, the high throughput screening mechanism has undergone radical changes with many disruptive technologies A new technology that has a serious impact on the status quo and changes the way people have been dealing with something, perhaps for decades. Music CDs all but wiped out the phonograph industry within a few years, and digital cameras are destined to eliminate the film industry.  yielding better results and requiring parallel improvements on the supporting instrumentation. Yet another significant development is the standardisation Noun 1. standardisation - the condition in which a standard has been successfully established; "standardization of nuts and bolts had saved industry millions of dollars"
standardization
 of assays with high content screening (HCS) analysis assuming enhanced emphasis in the screening process.

With improved focus on the volume of laboratory equipment used, miniaturisation offers the major advantage of alleviating the need for manual intervention between experiment cycles. Due to the advent of many miniaturisation technologies amidst other automation techniques, drug discovery is witnessing several changes, says the analyst of this research service. As a result, the market is witnessing increased deployment of automation processes by pharmaceutical and drug research companies to ensure accelerated development of safer drugs with optimal research and development (R&D) costs.

Configurability Essential to Overcome Hurdles in Customised Automation Devices

Automated liquid handling workstations backed up by robotic systems robotic system An integrated system of devices that automate production and manufacturing of goods and services Surgery An AI-based surgical assistant system, which processes sensory input from haptic interfaces and/or allows surgeons to act with more accuracy than  are lending flexibility to automation systems, providing the benefit of having specialised modular work cells for customised tasks. Automated compound management is gradually adapting to robotic and automated dispensing dispensing

provision of drugs or medicines as set out properly on a lawful prescription. A prescription can only be filled, the drugs supplied, by a registered pharmacist, veterinarian, dentist or member of the medical profession.
 environments for plate reformatting, thereby keeping pace with the miniaturised plate formats. In comparison to the automated compound handling segment, the automated liquid handling and robotic systems segments are likely to exhibit slower growth rates Growth Rates

The compounded annualized rate of growth of a company's revenues, earnings, dividends, or other figures.

Notes:
Remember, historically high growth rates don't always mean a high rate of growth looking into the future.
. However, with the concept of miniaturisation and the combination of microfluidics and nanotechnology likely to gain momentum, they are expected to display improved growth in future. Meanwhile, in view of the ongoing technological advances, the microplate reader market segment is expected to witness steady growth.

The high price sensitivity of biological consumables is likely to hamper the development of the miniaturisation technology. The growing demand for miniaturisation is leading to an increase in the level of complexity in assay design and development, remarks the analyst. While microfluidics and new technologies have identified minimal use of consumables, there has been a surge in the reagent reagent /re·a·gent/ (re-a´jent) a substance used to produce a chemical reaction so as to detect, measure, produce, etc., other substances.

re·a·gent
n.
 budget in response to rising high throughput and ultra-high throughput screening needs. Hence, to sustain overall market growth, niche participants would do well to identify early customers and their requirements and subsequently focus on product implementation. Moreover, providing reproducible solutions with easily configurable software architecture will enable automation vendors to gain a competitive edge in the market.

For more information visit http://www.researchandmarkets.com/reports/c48920

Source: Frost & Sullivan
COPYRIGHT 2007 Business Wire
No portion of this article can be reproduced without the express written permission from the copyright holder.
Copyright 2007, Gale Group. All rights reserved. Gale Group is a Thomson Corporation Company.

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Date:Jan 23, 2007
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