Compugen Licenses Gencarta -TM- Database to Albert Einstein College of Medicine and Weizmann Institute of Science.Business Editors & Health/Medical Writers BIOWIRE2K PRINCETON, N.J. & TEL AVIV Tel Aviv (tĕl əvēv`), city (1994 pop. 355,200), W central Israel, on the Mediterranean Sea. Oficially named Tel Aviv–Jaffa, it is Israel's commercial, financial, communications, and cultural center and the core of its largest , Israel--(BW HealthWire)--July 23, 2001 Compugen Ltd. (Nasdaq:CGEN CGEN Convective Sigmet Generation ) announced today that it has signed agreements with the Albert Einstein College of Medicine
The Albert Einstein College of Medicine (AECOM) is a graduate school of Yeshiva University. It is a private medical school located in the Jack and Pearl Resnick Campus of Yeshiva University in the Morris Park of Yeshiva University Yeshiva University, in New York City; mainly coeducational; begun 1886 as Yeshiva Eitz Chaim, a Jewish theological seminary, chartered 1928 as Rabbi Isaac Elchanan Theological Seminary and Yeshiva College; renamed 1945. and the Weizmann Institute of Science The Weizmann Institute of Science (מכון ויצמן למדע) is a world-renowned institute of higher learning and research in Rehovot, Israel. to provide them with Gencarta(TM), Compugen's annotated genome, transcriptome The transcriptome is the set of all messenger RNA (mRNA) molecules, or "transcripts", produced in one or a population of cells. The term can be applied to the total set of transcripts in a given organism, or to the specific subset of transcripts present in a particular cell type. and proteome pro·te·ome n. The complete set of proteins that are produced by the genes of an organism. proteome the entire complement of proteins produced by a cell. database. Financial terms of the agreements were not disclosed. "We are very pleased about the prospects of using Gencarta. It will significantly enrich our capacity to harvest the human genome The human genome is the genome of Homo sapiens, which is composed of 24 distinct pairs of chromosomes (22 autosomal + X + Y) with a total of approximately 3 billion DNA base pairs containing an estimated 20,000–25,000 genes. and to perform basic research in diverse realms of biology, biochemistry and genetics," said Professor Doron Lancet, Head of the Weizmann Institute's Crown Human Genome Center. "With its high quality of data and unique interface, Gencarta complements the set of tools we already have at our disposal." "Gencarta complements our established functional genomics Noun 1. functional genomics - the branch of genomics that determines the biological function of the genes and their products genomics - the branch of genetics that studies organisms in terms of their genomes (their full DNA sequences) program and will greatly accelerate disease-oriented gene discovery by investigators at our institution," stated Erwin P. Bottinger, M.D., Director of the Albert Einstein Biotechnology Center, Albert Einstein College of Medicine of Yeshiva University. Gencarta is a comprehensive annotated genome, transcriptome and proteome database accessible through flexible query tools for advanced post-genomic research. This comprehensive database is designed to assist in rapid target discovery processes and to increase the success of experiment design and implementation. Based on Compugen's LEADS platform, Gencarta provides a comprehensive view of the transcriptome, the biological bridge between genes and their coded proteins. The creation of this view requires the correct predictive modeling of underlying biological processes, in particular alternative splicing Alternative splicing is the RNA splicing variation mechanism in which the exons of the primary gene transcript, the pre-mRNA, are separated and reconnected so as to produce alternative ribonucleotide arrangements. , which has been an integral part of the LEADS platform since its inception. The periodic application by Compugen of LEADS analysis and data mining tools to both genomic and expressed sequence databases, results in one comprehensive and growing data source, which currently includes tens of thousands of genes, more than 150,000 annotated predicted splice variants and their derived proteins, SNPs, alignment of ESTs to known mRNAs and annotated genomic information. LEADS gene predictions have been tested in hundreds of cases and verified with a success rate of over 90% of these cases, in Compugen's molecular biology molecular biology, scientific study of the molecular basis of life processes, including cellular respiration, excretion, and reproduction. The term molecular biology was coined in 1938 by Warren Weaver, then director of the natural sciences program at the Rockefeller laboratory. About Weizmann Institute of Science The Weizmann Institute of Science is a major center of scientific research and graduate study located in Rehovot, Israel. Its 2,500 scientists, students and support staff are engaged in more than 1,000 research projects across the spectrum of contemporary science. About Albert Einstein College of Medicine Albert Einstein College of Medicine of Yeshiva University, established in 1955, has advanced rapidly to the front rank among the nation's leading centers for medical research and education. It is consistently among the national leaders in terms of peer-reviewed research support. In fiscal year 2000, Einstein received more than $113 million in research grants from the U.S. National Institutes of Health. Particular areas of research strength for which Einstein is widely renowned include Alzheimer's disease Alzheimer's disease (ăls`hī'mərz, ôls–), degenerative disease of nerve cells in the cerebral cortex that leads to atrophy of the brain and senile dementia. , neuroscience, cancer, heart disease, liver diseases, immunology, and molecular genetics molecular genetics n. The branch of genetics that deals with hereditary transmission and variation on the molecular level. . About Compugen Compugen (Nasdaq:CGEN) develops and markets platforms, tools and products that accelerate post-genomic research, the advanced study of proteins and protein pathways, and drug target discovery. Compugen's in-house molecular biology laboratories conduct original genomic and proteomic research and also provide validation for Compugen's methodologies. Products commercialized to date include: LEADS, Gencarta, DNA Chip design, Z3, ProtoCall, LabOnWeb.com and Bioccelerators. For additional information, please visit Compugen's Corporate Web Site at www.cgen.com and the Company's Internet research engine for molecular biologists, www.LabOnWeb.com. This press release contains "forward-looking statements." These statements include words like "may," "expects," "believes," and "intends," and describe opinions about future events. These forward-looking statements are subject to risks and uncertainties that may cause the actual results, performance or achievements of Compugen to be materially different from any future results, performance or achievements expressed or implied by such forward-looking statements. Some of these risks are: changes in relationships with collaborators; the impact of competitive products and technological changes; risks relating to the development of new products; the ability to implement technological improvements; the ability of Compugen to obtain and retain customers. These and other factors are identified and more fully explained under the heading "Risk Factors" in Compugen's Registration Statement on Form F-1 filed with the Securities and Exchange Commission. |
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