Company Profile for Phylonix.Business Editors/Health/Medical Writers --(BUSINESS WIRE) Phylonix is a Contract Research Organization providing in vivo in vivo /in vi·vo/ (ve´vo) [L.] within the living body. in vi·vo adj. Within a living organism. in vivo adv. zebrafish assays for drug screening and target validation. The Company has developed general and organ specific toxicity toxicity /tox·ic·i·ty/ (tok-sis´i-te) the quality of being poisonous, especially the degree of virulence of a toxic microbe or of a poison. tests, as well as other drug screening assays such as apoptosis apoptosis or programmed cell death Mechanism that allows cells to self-destruct when stimulated by the appropriate trigger. It may be initiated when a cell is no longer needed, when a cell becomes a threat to the organism's health, or for other reasons. and angiogenesis angiogenesis /an·gio·gen·e·sis/ (-jen´e-sis) vasculogenesis; development of blood vessels either in the embryo or in the form of neovascularization or revascularization. an·gi·o·gen·e·sis n. . Effect of drug treatment can be observed visually in transparent zebrafish embryos, and quantitative endpoint assays can be performed using microplate readers, in a format similar to cell based assays. Because in vivo zebrafish assays are more informative than cell based assays, and are faster and more cost-effective than assays using mammalian mammalian emanating from or pertaining to mammals. animals, the Company's drug screening system can streamline the pre-clinical drug development process. In addition to drug screening, the Company conducts custom designed studies, such as gene function analyses using gene knockdown
A gene knockdown is either a genetically modified organism that carries one or more genes in its chromosomes that has been made less active or had its "expression" reduced or is the use of a reagent approaches. For further information about the services provided by Phylonix, please consult the Company's homepage at http://www.phylonix.com or contact us at info@phylonix.com.
Company: Phylonix
Headquarters Address: 100 Inman Street
Suite 300
Cambridge, MA 02139
Main Telephone: 617-441-6700
Website: www.phylonix.com
Type of Organization: Private
Industry: Health: Biotechnology
Key Executives: President and CEO: Patricia McGrath
Business Development
Contact: Chaoyong Ma
Phone: 617-441-6700
Email: chaoyong@phylonix.com
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