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CombiMatrix Corporation Completes Major Milestone in Strategic Alliance with Roche.


Business Editors & Health/Medical Writers

BIOWIRE2K

SEATTLE--(BW HealthWire)--Jan. 8, 2002

CombiMatrix Corporation, a majority owned subsidiary of Acacia acacia (əkā`shə), any plant of the large leguminous genus Acacia, often thorny shrubs and trees of the family Leguminosae (pulse family).  Research Corp. (NASDAQ NASDAQ
 in full National Association of Securities Dealers Automated Quotations

U.S. market for over-the-counter securities. Established in 1971 by the National Association of Securities Dealers (NASD), NASDAQ is an automated quotation system that reports on
:ACRI), announced today that the company has completed a major milestone in its strategic alliance with Roche Applied Science.

CombiMatrix has demonstrated several key performance metrics Performance metrics are measures of an organizations activities and performance. Performance metrics should support a range of stakeholder needs from customers, shareholders to employees [1].  of its custom in-situ microarray system. CombiMatrix is developing a hybridization-reader instrument for the fully automated processing and imaging of microarrays contained in closed monocassettes. The CombiMatrix chip technology enables flexible and fast custom manufacturing of microarrays by in-situ oligo synthesis. Under the terms of the agreement, Roche will purchase and market the hybridization-reader instrument, flexible custom arrays, and pre-designed "catalogue" arrays in combination with its own matching labeling and hybridization hybridization /hy·brid·iza·tion/ (hi?brid-i-za´shun)
1. crossbreeding; the act or process of producing hybrids.

2. molecular hybridization

3.
 reagents as well as bioinformatic tools. In phase two of the agreement, Roche will market CombiMatrix' desktop synthesizers and will use production synthesizers for their own manufacturing of microarrays.

Dr. Amit Kumar, President and CEO (1) (Chief Executive Officer) The highest individual in command of an organization. Typically the president of the company, the CEO reports to the Chairman of the Board.  of CombiMatrix, stated, "Achievement of these critical milestones reflects the progress we have made since announcing our alliance with Roche Applied Science. Our goal is for CombiMatrix and Roche Diagnostics Roche Diagnostics Division is a subsidiary of Hoffmann-La Roche which manufactures equipment and reagents for research and medical diagnostic applications. Internally, it is organized into six major business areas: Roche Applied Science, Roche Centralized Diagnostics, Roche  to make this platform the standard for microarray research as well as molecular diagnostics."

Dr. Susanne Raehs, Head of Roche Applied Science, stated, "The CombiMatrix chip is a unique platform for a broad range of applications. It will substantially reduce the time and cost required to identify and develop pharmaceutical products and improve the diagnosis of complex diseases like cancer."

ABOUT COMBIMATRIX

CombiMatrix is developing a platform technology that has a wide range of applications, from DNA DNA: see nucleic acid.
DNA
 or deoxyribonucleic acid

One of two types of nucleic acid (the other is RNA); a complex organic compound found in all living cells and many viruses. It is the chemical substance of genes.
 synthesis/diagnostics to immunochemical im·mu·no·chem·is·try  
n.
The chemistry of immunologic phenomena, as of antigen-antibody reactions.



im
 detection. The platform allows the company to rapidly produce customizable active biochips, which are semiconductor-based tools for use in identifying and determining the roles of genes, gene mutations and proteins. The company is designing its products principally to be responsive to the needs of pharmaceutical, biotechnology, and academic researchers in analyzing raw genomic data in the discovery and development of pharmaceutical products. CombiMatrix's Web site is located at www.combimatrix.com.

ABOUT ROCHE

Headquartered in Basel, Switzerland, Roche is one of the world's leading research-oriented healthcare groups in the fields of pharmaceuticals, diagnostics and vitamins. Roche's products and services address prevention, diagnosis and treatment of diseases, thus enhancing well-being and quality of life. Roche's Diagnostics Division, the world leader in in vitro diagnostics In vitro diagnostic (IVD) tests are medical tests conducted in a test tube, or more generally in a controlled environment outside a living organism. In vitro means in glass in Latin.  with a uniquely broad product portfolio, supplies a wide array of innovative testing products and services to researchers, physicians, patients, hospitals and laboratories worldwide. Applied Science, a business area of Roche Diagnostics, develops and markets components and reagents for the pharmaceuticals and diagnostics industries, new technologies for medical research and innovative products for use in biotechnology.

ABOUT ACACIA RESEARCH CORPORATION

Acacia Research develops, licenses and provides products for the life science and media technology sectors. Acacia licenses its V-chip technology to television manufacturers and owns pioneering technology for digital streaming and video-on-demand. Acacia's CombiMatrix subsidiary is developing a bio-chip technology for the life science market. Acacia Research's Web site is located at www.acaciaresearch.com.

This release contains forward-looking statements within the meaning of the "safe harbor Safe Harbor

1. A legal provision to reduce or eliminate liability as long as good faith is demonstrated.

2. A form of shark repellent implemented by a target company acquiring a business that is so poorly regulated that the target itself is less attractive.
" provisions of the Private Securities Litigation Reform Act The Private Securities Litigation Reform Act of 1995 (PSLRA) implemented several significant substantive changes affecting certain cases brought under the federal securities laws, including changes related to pleading, discovery, liability, class representation and awards fees and  of 1995. These statements address future events and conditions concerning the Company's business plans. Such statements are subject to a number of factors and uncertainties, such as future economic conditions, changes in consumer demand, and legislative, regulatory and competitive developments. The Company expressly disclaims any future obligation or undertaking to update or revise any forward-looking statement contained herein.
COPYRIGHT 2002 Business Wire
No portion of this article can be reproduced without the express written permission from the copyright holder.
Copyright 2002, Gale Group. All rights reserved. Gale Group is a Thomson Corporation Company.

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Publication:Business Wire
Geographic Code:1USA
Date:Jan 8, 2002
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