CombiMatrix Announces Commercial Launch of CustomArray for DNA Expression Analysis.Business Editors/Health/Medical Writers BIOWIRE2K NEWPORT BEACH Newport Beach, residential and resort city (1990 pop. 66,643), Orange co., S Calif., on Newport Bay and the Pacific Ocean; inc. 1906. It is a popular seaside resort and yachting center. Manufactures include electrical and medical equipment, computers, boats, and adhesives. , Calif.--(BUSINESS WIRE)--March 1, 2004 Acacia Research Corporation (Nasdaq:CBMX)(Nasdaq:ACTG ACTG Acting ACTG AIDS Clinical Trial Group ACTG Actuating/Actuator ) announced today the launch of CombiMatrix group's CustomArray(TM) DNA Microarray DNA microarray A small solid support, usually a membrane or glass slide, on which sequences of DNA are fixed in an orderly arrangement. DNA microarrays are used for rapid surveys of the expression of many genes simultaneously, as the sequences contained on a platform, offering researchers the ability to order fully customizable arrays on demand. Researchers can order CustomArrays by accessing CombiMatrix's order site at www.customarray.com or by contacting CombiMatrix at 800-985-CBMX (2269). CustomArray is being introduced today to the research market at the annual meeting of the Association of Biomolecular Resource Facilities (ABRF ABRF Association of Biomolecular Resource Facilities ). The ABRF is the single largest gathering of core facility directors and decision makers. For the first time, customers will have the ability to order fully customizable microarrays in any desired quantity. Researchers simply submit lists of genes, target sequences, or probes. For use with GenBank(R) sequences, data can be specified by accession number Accession number may mean:
CustomArray from CombiMatrix greatly simplifies the order and production of custom microarrays, providing microarray users with a fast and flexible option for a wide range of research applications. CustomArrays are produced in a standard slide format, a configuration that is most familiar to researchers. The slide format can be seamlessly integrated into familiar procedures for hybridization hybridization /hy·brid·iza·tion/ (hi?brid-i-za´shun) 1. crossbreeding; the act or process of producing hybrids. 2. molecular hybridization 3. and washing. The slides can be imaged with most existing microarray scanners. Dr. Chi Yip Ho, Director, Microarray Laboratory at Mount Sinai Hospital Mount Sinai Hospital can refer to:
The commercial launch of CustomArray also provides customers with full access to CombiMatrix's suite of software applications, available at www.customarray.com. CombiMatrix has developed user-friendly applications for design submission, online ordering, and extraction of experimental results. Target Specifier(TM) allows researchers to specify the list of genes that will be studied on the array. The list is sent to CombiMatrix's Probe Design System(TM) where probe sequences are automatically designed for that experiment. Microarray Imager(TM) allows a customer to view the experimental results, extract the intensity data, and save the results in standard spreadsheet format. CustomArray users can look forward to many features including: -- No subscription or design fee -- No special equipment required -- Flexibility to study any genome, any gene, or virtually any probe sequence -- Delivery of custom microarrays within 10 days -- Standard microarray slide configuration -- Flexible ordering of one or one hundred microarrays -- Study of multiple genomes on the same chip CustomArrays are semiconductor-based arrays (approx. 1 cm2) integrated onto a standard 1" x 3" slide format. CustomArrays contain in situ In place. When something is "in situ," it is in its original location. synthesized oligonucleotides, prepared using CombiMatrix's patented virtual-flask technology. Sensitivity and performance metrics Performance metrics are measures of an organizations activities and performance. Performance metrics should support a range of stakeholder needs from customers, shareholders to employees [1]. are available from the company's web site and at www.customarray.com. About Acacia Research Corporation Acacia Research Corporation comprises two operating groups, Acacia Technologies
The CombiMatrix group is developing a platform technology to rapidly produce customizable active biochips, which are semiconductor-based tools for use in identifying and determining the roles of genes, gene mutations and proteins. CombiMatrix's technology has a wide range of applications including DNA DNA: see nucleic acid. DNA or deoxyribonucleic acid One of two types of nucleic acid (the other is RNA); a complex organic compound found in all living cells and many viruses. It is the chemical substance of genes. synthesis/diagnostics, siRNA synthesis, drug discovery, and immunochemical im·mu·no·chem·is·try n. The chemistry of immunologic phenomena, as of antigen-antibody reactions. im detection. CombiMatrix provides DNA arrays to researchers under the CustomArray(TM) brand. CombiMatrix's Express Track(SM) drug discovery program is a systems biology approach, using its technology, to target common viral diseases with siRNA compounds. The initial focus of Express Track(SM) includes the following viral diseases: Virus Collaborator SARS NIAID/USAMRIID HIV type 1 irsiCaixa-Dr. Bonaventura Clotet HIV type 2 To Be Announced West Nile virus To Be Announced Human Papillomavirus type 16 To Be Announced Human Herpes 8 (Kaposi's sarcoma) To Be Announced Smallpox (Variola) To Be Announced Influenza virus A To Be Announced Influenza virus B To Be Announced Hepatitis C To Be Announced CombiMatrix is also establishing applications of its arrays through other partnerships as follows:
Project Collaborator
Cancer Diagnosis (Lymphoma) University of Washington/Rational
Diagnostics
RNA Drug Targets Professor Gregory L. Verdine,
Harvard University
Parasite
Leishmania Seattle Biomedical Research
Institute
Trypasonoma Seattle Biomedical Research
Institute
The Acacia Technologies Group develops, acquires, and licenses patented technologies. Acacia's DMT See DSL. technology, which is supported by 5 U.S. and 31 foreign patents, relates to audio and audio/video transmission and receiving systems commonly known as audio-on-demand, video-on-demand, and audio/video streaming, and is used for distributing digital content via several means including Internet, cable, satellite and wireless systems. Acacia Research-Acacia Technologies (Nasdaq:ACTG) and Acacia Research-CombiMatrix (Nasdaq:CBMX) are both classes of common stock issued by Acacia Research Corporation and are intended to reflect the performance of the respective operating groups and are not issued by the operating groups. Information about Acacia Research Corporation and the Acacia Technologies group is available at www.acaciaresearch.com. Information about the CombiMatrix group is available at www.combimatrix.com. GenBank(R) is a registered trademark of the United States Department of Health and Human Services United States Department of Health and Human Services (USDHHS), n.pr a cabinet-level government organization comprising 12 agencies, including the Food and Drug Administration and the Centers for Disease Control and Prevention. . CustomArray(TM) is a trademark of CombiMatrix Corporation. Safe Harbor Safe Harbor 1. A legal provision to reduce or eliminate liability as long as good faith is demonstrated. 2. A form of shark repellent implemented by a target company acquiring a business that is so poorly regulated that the target itself is less attractive. Statement under the Private Securities Litigation Reform Act The Private Securities Litigation Reform Act of 1995 (PSLRA) implemented several significant substantive changes affecting certain cases brought under the federal securities laws, including changes related to pleading, discovery, liability, class representation and awards fees and of 1995: This news release contains forward-looking statements within the meaning of the "safe harbor" provisions of the Private Securities Litigation Reform Act of 1995. These statements are based upon our current expectations and speak only as of the date hereof. Our actual results may differ materially and adversely from those expressed in any forward-looking statements as a result of various factors and uncertainties, including the recent economic slowdown affecting technology companies, our ability to successfully develop products, rapid technological change in our markets, changes in demand for our future products, legislative, regulatory and competitive developments and general economic conditions. Our Annual Report on Form 10-K Form 10-K A report required by the SEC from exchange-listed companies that provides for annual disclosure of certain financial information. Form 10-K See 10-K. , recent and forthcoming Quarterly Reports on Form 10-Q Form 10-Q See 10-Q. , recent Current Reports on Forms 8-K and 8-K/A, and other SEC filings discuss some of the important risk factors that may affect our business, results of operations and financial condition. We undertake no obligation to revise or update publicly any forward-looking statements for any reason. Note to Editors: In the text, the term "cm2" stands for "centimeters squared." |
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