CombiChem appoints former Merck senior director as vice president of strategic development.LA JOLLA La Jolla (lə hoi`yə), on the Pacific Ocean, S Calif., an uninc. district within the confines of San Diego; founded 1869. The beautiful ocean beaches, in particular La Jolla shores and Black's Beach, and sea-washed caves attract visitors and , Calif.--(BUSINESS WIRE)--Jan. 20, 1995--CombiChem Inc., a newly established combinatorial-chemistry company, Friday announced that it has appointed Lynn H. Caporale, Ph.D., as vice president of strategic development. As senior director, scientific liaison, at Merck & Co. Inc., Caporale was responsible for identifying, tracking and acquiring breakthrough therapeutic agents and establishing strategic relationships with other pharmaceutical and biotechnology companies Top 100 Biotechnology Companies The following is a list of the top 100 biotechnology companies ranked by revenue. The first nine companies qualify for the list of the top 50 pharmaceutical companies. . Caporale will assist in CombiChem's efforts to establish strategic relationships and partnerships with companies in the pharmaceutical and biopharmaceutical industry, according to according to prep. 1. As stated or indicated by; on the authority of: according to historians. 2. In keeping with: according to instructions. 3. Robert A. Curtis, president and chief executive officer. "After more than a decade at Merck & Co., Dr. Caporale possesses extensive experience in fostering partnerships between small drug- discovery companies and large pharmaceutical corporations," said Curtis. "In her previous position, she was actively involved in assessing and acquiring drug-discovery technologies and coordinating strategic responses to breakthrough areas of science including the emergence of the combinatorial-chemistry field. Her decision to leave Merck to join CombiChem reflects her assessment of our unique comprehensive approach to combinatorial chemistry Combinatorial chemistry involves the rapid synthesis or the computer simulation of a large number of different but structurally related molecules. Introduction Synthesis of molecules in a combinatorial fashion can quickly lead to large numbers of molecules. and drug discovery." Prior to her appointment as senior director, Caporale held positions as director, scientific evaluation, and senior research fellow at Merck. Previously, she was an assistant professor of biochemistry, Georgetown University Georgetown University, in the Georgetown section of Washington, D.C.; Jesuit; coeducational; founded 1789 by John Carroll, chartered 1815, inc. 1844. Its law and medical schools are noteworthy, and its archives are especially rich in letters and manuscripts by and Schools of Medicine and Dentistry; a research associate at Rockefeller University; and an associate researcher at Memorial/Sloan-Kettering Cancer Center. Caporale is a member of the American Association for the Advancement of Science American Association for the Advancement of Science (AAAS), private organization devoted to furthering the work of scientists and improving the effectiveness of science in the promotion of human welfare. , the New York Academy of Sciences The New York Academy of Sciences is the third oldest scientific society in the United States. An independent, non-profit organization with more than 25,000 members in 140 countries, the Academy’s mission is to advance understanding of science and technology. and the Society for Molecular Recognition, and has published in a variety of peer-reviewed journals, including Cellular Immunology, Blood and The Proceedings of the National Academy of Sciences The Proceedings of the National Academy of Sciences of the United States of America, usually referred to as PNAS, is the official journal of the United States National Academy of Sciences. . Caporale received her doctorate in molecular biology molecular biology, scientific study of the molecular basis of life processes, including cellular respiration, excretion, and reproduction. The term molecular biology was coined in 1938 by Warren Weaver, then director of the natural sciences program at the Rockefeller from the University of California, Berkeley The University of California, Berkeley is a public research university located in Berkeley, California, United States. Commonly referred to as UC Berkeley, Berkeley and Cal . CombiChem's automated synthesis systems will have the advantage of being able to generate sufficient quantities of sample compounds to facilitate comprehensive and efficient screening and archiving of material. In addition, the company's libraries will be in structural classes designed to be of interest to pharmaceutical companies. "Dr. Caporale will assist me in our efforts to establish collaborations and alliances with major pharmaceutical and biopharmaceutical companies. Through these corporate relationships, we plan to offer customized combinatorial-chemistry services and products, license our automated compound synthesis systems, and transfer certain elements of our drug-discovery technology," added Curtis. "With the knowledge gained from the human genome project and the advances made in molecular modeling and rational drug design, we anticipate CombiChem's technology will serve to significantly close the gap between identifying a molecular target for disease intervention and the eventual discovery of an active therapeutic agent." CombiChem is a molecular-discovery company integrating combinatorial chemistry with computational drug design, bioinformatics and automated chemical synthesis to identify, optimize and enable broader patent protection for new pharmaceuticals. The company is designing and synthesizing libraries of low-molecular-weight, druglike molecules in formats that are compatible with the full spectrum of assay methods. CONTACT: CombiChem Inc., La Jolla Robert A. Curtis, 619/453-8090 or Keatinge/Seaton Communications Richard W. Keatinge, 619/625-2100 or Feinstein Partners Inc. Marcia A. Kean, 617/577-8110 |
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