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CombiChem Inc. and Roche Bioscience sign major drug discovery collaboration agreement.


SAN DIEGO San Diego (săn dēā`gō), city (1990 pop. 1,110,549), seat of San Diego co., S Calif., on San Diego Bay; inc. 1850. San Diego includes the unincorporated communities of La Jolla and Spring Valley. Coronado is across the bay.  and PALO ALTO Palo Alto, city, California
Palo Alto (păl`ō ăl`tō), city (1990 pop. 55,900), Santa Clara co., W Calif.; inc. 1894. Although primarily residential, Palo Alto has aerospace, electronics, and advanced research industries.
, Calif.--(BUSINESS WIRE)--Nov. 6, 1996-- CombiChem Inc. and Roche Bioscience Wednesday announced the commencement of a major collaboration involving multiple drug discovery targets.

The companies will initially collaborate on three projects -- one each in lead generation, lead evolution and lead optimization. According to according to
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 the terms of the agreement, the collaboration may expand to include additional projects in the future. While specific financial terms were not disclosed, Roche Bioscience made an upfront payment to CombiChem and will provide research funding Research funding is a term generally covering any funding for scientific research, in the areas of both "hard" science and technology and social science. The term often connotes funding obtained through a competitive process, in which potential research projects are evaluated and  and performance-based milestone payments. Roche Bioscience retains exclusive global rights to develop and market the products resulting from the collaboration and CombiChem will receive royalty payments on marketed products.

"The diverse array of targets we selected for this collaboration are aimed at bringing a number of novel therapeutic entities to the market," said Robert Booth, Ph.D., senior vice president and head of the Inflammatory Diseases Business Unit at Roche Bioscience. "We expect that CombiChem's Drug Discovery Engine and Universal Informer Informer
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 Library will add a powerful new technology to our drug discovery process and enable us to discover, evolve, and optimize lead compounds within significantly shorter periods of time."

Vicente Anido, Jr., Ph.D., chief executive officer and president of CombiChem, said: "The agreement with Roche Bioscience is significant because it is a clear affirmation from a major multi-national pharmaceutical company that it has confidence in CombiChem's Drug Discovery Engine and its integration of medicinal chemistry Medicinal or pharmaceutical chemistry is a scientific discipline at the intersection of chemistry and pharmacology involved with designing, synthesizing and developing pharmaceutical drugs.  with small library design technology. The most comprehensive and extensive agreement for CombiChem to date, this is the first step in what we expect will be a long-term relationship between our company and Roche Bioscience."

CombiChem, founded in 1994, is a privately held company privately held company

A firm whose shares are held within a relatively small circle of owners and are not traded publicly.
 with headquarters in San Diego. CombiChem accelerates drug discovery through the integration of medicinal chemistry and small library design technology.

Located in Palo Alto, Roche Bioscience is a research-based, business-oriented enterprise dedicated to the discovery and early clinical development of innovative prescription drugs prescription drug Prescription medication Pharmacology An FDA-approved drug which must, by federal law or regulation, be dispensed only pursuant to a prescription–eg, finished dose form and active ingredients subject to the provisos of the Federal Food, Drug, . Roche Bioscience is a member of the Roche Group, which has headquarters in Basel, Switzerland.

CONTACT: Friestedt International (for CombiChem)

Susanne Friestedt

Phone: 619/223-8844

Fax: 619/223-4232

E-mail: friestintl@aol.com

or

CombiChem Inc., San Diego

Vicente Anido, Jr., Ph.D.

Phone: 619/530-0484

Fax: 619/530-9998

E-mail: vanido.combichem.com

or

Roche Bioscience, Palo Alto

Nancy Peterson

Phone: 415/855-5567

Fax: 415/855-5526

E-mail: nancy.peterson@roche.com
COPYRIGHT 1996 Business Wire
No portion of this article can be reproduced without the express written permission from the copyright holder.
Copyright 1996, Gale Group. All rights reserved. Gale Group is a Thomson Corporation Company.

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Publication:Business Wire
Date:Nov 6, 1996
Words:398
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