Columbia Scientists Rapidly Grow Bone Tissue.Using stem cell lines not typically combined, researchers at Columbia University Medical Center Columbia University Medical Center is the name of the medical complex associated with Columbia University, and covers several blocks (primarily between 165th and 168th Streets from the Henry Hudson Parkway to Audubon Avenue) in the Washington Heights section of Manhattan. in New York New York, state, United States
New York, Middle Atlantic state of the United States. It is bordered by Vermont, Massachusetts, Connecticut, and the Atlantic Ocean (E), New Jersey and Pennsylvania (S), Lakes Erie and Ontario and the Canadian province of have designed a new way to "grow" bone and other tissues.
Researchers led by Jeremy Mao, Ph.D., have co-transplanted hematopoietic hematopoietic /he·ma·to·poi·et·ic/ (-poi-et´ik)
1. pertaining to hematopoiesis.
2. an agent that promotes hematopoiesis.
1. pertaining to or affecting the formation of blood cells. and mesenchymal stem/progenitor cells to promote the regeneration of vascularized tissues.
They found that the tissue regenerated in bone more rapidly than when either type of stem cell stem cell
In living organisms, an undifferentiated cell that can produce other cells that eventually make up specialized tissues and organs. There are two major types of stem cells, embryonic and adult. was used alone. The work, published in the Public Libraries of Science, takes a new approach. Rarely have mesenchymal and hematopoietic cells been delivered in combination to heal defects or treat diseases - partially due to the separate research communities in which these two cell groups are studied.
Dr. Mao and colleagues demonstrated that when human mesenchymal stem/progenitor cells were seeded in micropores of 3D calcium phosphate scaffolds, followed by infusion of gel-suspended CD34+ hematopoietic cells, greater vascularization vascularization /vas·cu·lar·iza·tion/ (vas?ku-ler-i-za´shun)
1. the process of becoming vascular.
3. the surgically induced development of vessels in a tissue. was seen in mice than when mesenchymal cells were used alone.