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Columbia Laboratories announces the acquisition of a new natural bioadhesive technology.


MIAMI--(BUSINESS WIRE)--July 6, 1995--Columbia Laboratories, Inc. (AMEX AMEX

See: American Stock Exchange
:COB) today announced it has acquired worldwide rights to a newly developed, protein based, bioadhesive technology for all applications in women's health care.

The inventor, Professor Jean-Marc Alche of th Faculte de Pharmacie, at the University of Clermont-Ferrand, France, a world authority on bioadhesive delivery systems, has applied this new technology to buccal buc·cal
adj.
1. Of, relating to, adjacent to, or in the direction of the cheek.

2. Of or relating to the mouth cavity.


buccal
, vaginal, nasal and rectally delivered products.

This natural protein based bioadhesive technology is a complement to Columbia's original patented bioadhesive delivery system and enhances the company's ability to further expand its portfolio of unique products in women's health care. When drugs and hormones are given orally, they are often inactivated inactivated

rendered inactive; the activity is destroyed.


inactivated viruses
treated so that they are no longer able to produce evidence of growth or damaging effect on tissue.
 after ingestion ingestion /in·ges·tion/ (-chun) the taking of food, drugs, etc., into the body by mouth.

in·ges·tion
n.
1. The act of taking food and drink into the body by the mouth.

2.
 by the liver; this is known as the first liver pass effect. This new technology facilitates the process of developing buccal patches that can be used to avoid first pass inactivation inactivation /in·ac·ti·va·tion/ (in-ak?ti-va´shun) the destruction of biological activity, as of a virus, by the action of heat or other agent.  by the liver. Early clinical trials have demonstrated that buccal patches developed with this newly acquired technology can deliver drugs through the buccal cavity for up to 24 hours.

"This new bioadhesive delivery system expands our range in women's health care product development by making it possible to deliver hormones from buccal patches that are smaller than a contact lens," said William J. Bologna, Chairman of the Board.

Columbia Laboratories, Inc. is a U.S.-based international pharmaceutical company, dedicated to the development of women's prescription and over-the-counter products, including those which help prevent sexually transmitted diseases Sexually transmitted diseases

Infections that are acquired and transmitted by sexual contact. Although virtually any infection may be transmitted during intimate contact, the term sexually transmitted disease is restricted to conditions that are largely
. Columbia's products primarily utilize the Company's patented bioadhesive delivery technology.

CONTACT: Columbia Laboratories, Inc.

Margaret J. Roell, 305/860-1692
COPYRIGHT 1995 Business Wire
No portion of this article can be reproduced without the express written permission from the copyright holder.
Copyright 1995, Gale Group. All rights reserved. Gale Group is a Thomson Corporation Company.

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Publication:Business Wire
Date:Jul 6, 1995
Words:261
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