Coenzyme Q10 for melanoma.In a non-randomized trial, 32 patients with surgically removed stage I or II melanoma received 400 mg per day of coenzyme Q coenzyme Q n. Ubiquinone. 10 (CoQ10) for three years, while 49 age- and sex-matched patients with stage I or II melanoma served as controls. All patients were treated with recombinant interferon alpha-2b throughout the trial. After five years, metastases Metastasis (plural, metastases) A tumor growth or deposit that has spread via lymph or blood to an area of the body remote from the primary tumor. Mentioned in: Malignant Melanoma had occurred in 26.5% of patients in the control group and in 3.1% of those receiving CoQ10 (p = 0.006). Comment: CoQ10 has demonstrated anti-cancer effects in animal studies and preliminary human trials. CoQ10 levels have been found to be low in patients with melanoma. The results of the present study suggest that supplementation with CoQ10 as an adjunct to interferon alpha-2b can decrease the rate of metastases in patients with stage I or II melanoma. Rusciani L, et al. Recombinant interferon alpha-2b and coenzyme Q10 as a postsurgical adjuvant therapy Adjuvant therapy A treatment done when there is no evidence of residual cancer in order to aid the primary treatment. Adjuvant treatments for endometrial cancer are radiation therapy, chemotherapy, and hormone therapy. for melanoma: a 3-year trial with recombinant interferon-alpha and 5-year follow-up. Melanoma Res. 2007;17:177-183. |
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