Co-development agreement.Cytrx's announcement wasn't the only local news coming out of the JPMorgan conference. Santa Monica Santa Monica (săn`tə mŏn`ĭkə), city (1990 pop. 86,905), Los Angeles co., S Calif., on Santa Monica Bay; inc. 1886. Tourism and retailing are important, and the city has motion-picture, biotechnology, and software industries. drug developer Agensys Inc. announced a collaboration agreement with Seattle Genetics Inc., a rising biotech star. The multi-year deal gives Agensys access to technology that will enable it to beef up its cancer-fighting monoclonal antibodies This is a list of monoclonal antibodies, antibodies which are clones of a single parent cell. When used as medications, the generic names end in -mab (see "Nomenclature of monoclonal antibodies"). , synthesized versions of the basic human mechanism that fight off disease. Seattle Genetics' has a technology called anti-body drug conjugate conjugate /con·ju·gate/ (kon´jdbobr-gat) 1. paired, or equally coupled; working in unison. 2. a conjugate diameter of the pelvic inlet; used alone usually to denote the true conjugate diameter; see (ADC (1) See A/D converter. (2) (Apple Display Connector) A peripheral connector from Apple that combines digital video display, USB and power in one cable. ) therapy that allows cancer-fighting toxins to be delivered to solid tumors without damaging nearby healthy cells. That should make the drugs derived from Agensys' monoclonal antibodies more effective in killing advanced cancers of the lung and bladder. Under the agreement, Agensys will use ADC in developing four proprietary drug targets, with some co-funded and co-developed with Seattle Genetics. The first identified target is a prostate and colon treatment. Privately held Agensys doesn't have any products on the market yet, but is in clinical trials with a therapy, to treat prostate, pancreatic and bladder cancers bladder cancer Malignant tumour of the bladder. The most significant risk factor associated with bladder cancer is smoking. Exposure to chemicals called arylamines, which are used in the leather, rubber, printing, and textiles industries, is another risk factor. that it is co-developing with Merck. Seattle Genetics, based in Bothel, Wash., has a separate global licensing agreement with Genentech Inc. that was the big buzz of the conference. |
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