Cloned cows provide company for Dolly.In the two years since she was born. Dolly probably has never worried about being the only mammal ever cloned from the DNA DNA: see nucleic acid.
or deoxyribonucleic acid
One of two types of nucleic acid (the other is RNA); a complex organic compound found in all living cells and many viruses. It is the chemical substance of genes. of an adult cell. But for some scientists trained to accept no result unless it can be duplicated, the sheep's singular life has been disquieting dis·qui·et
tr.v. dis·qui·et·ed, dis·qui·et·ing, dis·qui·ets
To deprive of peace or rest; trouble.
Absence of peace or rest; anxiety.
Uneasy; restless. .
News from the Ishikawa Prefectural pre·fec·ture
1. The district administered or governed by a prefect.
2. The office or authority of a prefect.
3. The residence or housing of a prefect. Livestock Research Center in Ishikawa Ken. Japan should cause such skeptical souls to sign in relief. Scientists there announced this week the birth of two calves created by the cloning of cow cells.
In a process called nuclear transplantation Noun 1. nuclear transplantation - moving a cell nucleus and its genetic material from one cell to another
SCNT, somatic cell nuclear transfer, somatic cell nuclear transplantation
biological research - scientific research conducted by biologists , which was also used to create Dolly (SN: 4/5/97 p. 214/, the researchers reportedly fused cells from an adult cow's uterus to cow eggs whose own DNA had been removed. The substitute DNA from the uterine uterine /uter·ine/ (u´ter-in) pertaining to the uterus.
Of, relating to, or in the region of the uterus. cells guided me eggs as they developed in/o embryos, which were then implanted into live surrogate mothers. The mothers each harboring two embryos, were due m mid-August but one gave birth prematurely on Sunday, the Japanese group announced.
"This would be the first confirmation of adult donor cells working," says George E. Seidel sei·del
A beer mug.
[German, from Middle High German sdel, from Latin situla, bucket.]
Noun 1. Jr. of the Animal Reproduction and Biotechnology Laboratory at Colorado State University Colorado State University, at Fort Collins; land-grant with state and federal support; chartered 1870, opened 1879 as an agricultural college, assumed present name in 1957. There is a veterinary teaching hospital, an agricultural campus, and a research campus. in Fort Collins.
Seidel and other scientists note that it's difficult to judge the legitimacy of me new cloning work given the few details released so far. The Japanese group has nor yet publicly described the genetic tests conducted to confirm that their newborn calves are indeed clones, and it has not published a report on the experiment.
"I hope it's correct. It's exciting if it is. but we need more information before making any definitive conclusions." notes cloning researcher James M. Robl of the University of Massachusetts The system includes UMass Amherst, UMass Boston, UMass Dartmouth (affiliated with Cape Cod Community College), UMass Lowell, and the UMass Medical School. It also has an online school called UMassOnline. tn Amherst.
This week's announcement from Japan may have stolen thunder from another cloning effort, if the scientific rumor mill is to be believed. For several months, gossip has circulated among scientists that a research team headed by Ryuzo Yanagimachi of the University of Hawaii (body, education) University of Hawaii - A University spread over 10 campuses on 4 islands throughout the state.
See also Aloha, Aloha Net. School of Medicine in Honolulu has cloned mice from adult mouse cells.
According to media reports, Yanagimachi hinted at the accomplishment at a recent meeting but did not provide details. When contacted by Science News. Yanagimachi declined to comment other than to note that a paper describing his group's research would appear this month in a scientific journal.
New cloning reports may nor put to rest all doubts about Dolly--some investigators have speculated that she was inadvertently cloned from a fetal rather man adult cell. They should. however, resolve the issue of whether cloning from adult cells is possible.
Still the practical significance of this type of cloning remains unclear. Researchers can develop many of cloning's applications, such as the addition of human genes to animals, without the use of adult cells.
Last year, the investigators who created Doily unveiled Polly a lamb cloned from fetal sheep cells to which a human gene bad been added SN: 8/23/97, p. 127). And in the May 22 SCIENCE. Robl and his colleagues describe genetically altered calves similarly cloned from fetal cow cells.