CiVentiChem Announces Research and Development Collaboration with Tranzyme Pharma.RESEARCH TRIANGLE PARK Research Triangle Park, research, business, medical, and educational complex situated in central North Carolina. It has an area of 6,900 acres (2,795 hectares) and is 8 × 2 mi (13 × 3 km) in size. Named for the triangle formed by Duke Univ. , N.C. & SHERBROOKE, Quebec “Sherbrooke” redirects here. For other uses, see Sherbrooke (disambiguation). Sherbrooke (2006 population: 147,427) is a city in south-eastern Quebec, Canada, the only major city in the Eastern Townships. -- CiVentiChem, L.L.C., a provider of integrated chemistry services, announced today that it has entered into a research and development collaboration with Tranzyme Pharma Inc., a leading biopharmaceutical company developing novel mechanism-based therapeutics for the treatment of gastrointestinal (GI) disorders. Under the terms of the agreement, CiVentiChem will provide research services in the areas of medicinal chemistry Medicinal or pharmaceutical chemistry is a scientific discipline at the intersection of chemistry and pharmacology involved with designing, synthesizing and developing pharmaceutical drugs. , custom compound synthesis and process development. CiVentiChem will provide services to Tranzyme Pharma from its facility in Research Triangle Park, NC, as well as through its subsidiary, Indus Biosciences, located in Hyderabad, India. CiVentiChem has proven expertise in executing quality comprehensive services in the areas of discovery support, lead optimization, contract research, custom synthesis of APIs, intermediates & NMEs, process development, and cGMP manufacturing for pharmaceutical and biotechnology companies Top 100 Biotechnology Companies The following is a list of the top 100 biotechnology companies ranked by revenue. The first nine companies qualify for the list of the top 50 pharmaceutical companies. . CiVentiChem will apply its expertise with the goal of accelerating the development of Tranzyme Pharma's novel small molecule products for the treatment of post-operative ileus Ileus Definition Ileus is a partial or complete non-mechanical blockage of the small and/or large intestine. The term "ileus" comes from the Latin word for colic. , gastroparesis, and other GI disorders. Financial details of the agreement were not disclosed. "We are very pleased that Tranzyme Pharma has chosen CiVentiChem and Indus Biosciences for our value-added services A value-added service (VAS) is a telecommunications industry term for non-core services or, in short, all services beyond standard voice calls and fax transmissions. in process development and custom chemistry to complement their internal capabilities," said Bhaskar Venepalli, Ph.D., President for CiVentiChem. "CiVentiChem's aim in this collaboration is to support Tranzyme Pharma in its small molecule programs by increasing productivity and shortening the time required for product development." "We selected CiVentiChem for its ability to consistently design and implement complex chemistry on demand while delivering quality results," said Mark L. Peterson, Vice President of Operations for Tranzyme Pharma. "CiVentiChem offers us a unique advantage by leveraging extensive chemistry expertise in India through its operations in Hyderabad. We look forward to their continued involvement in our drug development programs." CiVentiChem is a leading provider of R&D services in the areas of discovery support, lead optimization, contract research, process development and custom synthesis to life sciences companies. CiVentiChem's goal is to satisfy the unmet needs for gram to kilogram kilogram, abbr. kg, fundamental unit of mass in the metric system, defined as the mass of the International Prototype Kilogram, a platinum-iridium cylinder kept at Sèvres, France, near Paris. quantities of novel chemical building blocks, pharmaceutical intermediates and APIs to support the R&D efforts of its pharmaceutical, agrochemical agrochemical Any chemical used in agriculture, including chemical fertilizers, herbicides, and insecticides. Most are mixtures of two or more chemicals; active ingredients provide the desired effects, and inert ingredients stabilize or preserve the active ingredients or aid and biotechnology customers. Since its formation in 1994, CiVentiChem has established excellent working relationships with numerous leading pharmaceutical and biotechnology companies, providing contract R&D and custom synthesis services. More information about the capabilities of CiVentiChem and Indus Biosciences can be obtained at the web site, www.cvchem.com and www.indusbio.com. Tranzyme Pharma is a leading biopharmaceutical company developing novel orally bioavailable, small molecule therapeutics for the treatment of gastrointestinal (GI) diseases. The Company's candidate drugs originate from its own discovery pipeline of proprietary compounds with high affinity for validated and druggable targets in the GI tract. Tranzyme is developing mechanism-based therapeutics for post-operative ileus, diabetic gastroparesis, irritable bowel syndrome irritable bowel syndrome (IBS), condition characterized by frequently alternating constipation and diarrhea in the absence of any disease process. It is usually accompanied by abdominal pain, especially in the lower left quadrant, bloating, and flatulence. (diarrhea-type) and functional dyspepsia dyspepsia: see indigestion. and is on track to enter the clinic with its first product by the end of 2005. Tranzyme is leveraging its technologies through internal programs and partnerships to drive the discovery and development of new therapeutics. For more information, please visit: www.tranzyme.com. |
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