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Church & Dwight reports pharmaceutical research on a new drug for prevention and treatment of osteoporosis and hypertension.


Dwight Co., Inc. (NYSE NYSE

See: New York Stock Exchange
:CHD CHD coronary heart disease.

ChD
abbr.
Latin Chirurgiae Doctor (Doctor of Surgery)


CHD,
n.pr See disease, coronary heart.


CHD

canine hip dysplasia.
) said today that it has been developing a drug for the prevention and treatment of osteoporosis and hypertension.

The new agent, XOSTEN(TM), a controlled-release dosage form of potassium bicarbonate potassium bicarbonate
n.
A compound in the form of a white powder or colorless crystals, used in baking powder and as an antacid medicine.


potassium bicarbonate

K+Care ET

Pharmacologic class:
 for oral administration, is presently undergoing Phase II/III clinical studies under Investigational New Drug applications filed with the U.S. Food & Drug Administration. The Company has invested approximately $20 million, all of which has been charged against income as incurred, and plans to continue to invest as appropriate. Various aspects of XOSTEN technology, and its uses, are the subject of issued and pending U.S. and foreign patents.

Church & Dwight stated that they are seeking alliances for further development and the global marketing of XOSTEN. As the first step, Church & Dwight has granted co-marketing rights in Europe and certain parts of Asia to Nycomed Pharma AS of Oslo, Norway, in return for conducting the clinical studies needed for registrations in those areas. Nycomed, a major European pharmaceutical company, is a subsidiary of Hafslund Nycomed, the leader in contrast agents for medical imaging.

Dwight C. Minton, Church & Dwight's Chairman, stated, "This program evolved out of our long-term interest in basic research on sodium bicarbonate and addressed widespread concerns about the role of dietary sodium in hypertension. Pioneering research at the University of California The University of California has a combined student body of more than 191,000 students, over 1,340,000 living alumni, and a combined systemwide and campus endowment of just over $7.3 billion (8th largest in the United States).  in San Francisco demonstrated that sodium bicarbonate (baking soda), unlike sodium chloride (table salt), does not induce hypertension. Further, it was demonstrated that potassium bicarbonate significantly lowers blood pressure in hypertensive hypertensive /hy·per·ten·sive/ (-ten´siv)
1. characterized by increased tension or pressure.

2. an agent that causes hypertension.

3. a person with hypertension.
 patients. More recent work relative to osteoporosis, published in The New England Journal of Medicine The New England Journal of Medicine (New Engl J Med or NEJM) is an English-language peer-reviewed medical journal published by the Massachusetts Medical Society. It is one of the most popular and widely-read peer-reviewed general medical journals in the world.  in 1994, describes the remarkable effects of potassium bicarbonate in conserving calcium and phosphorous phos·pho·rous
adj.
Of, relating to, or containing phosphorus, especially with a valence of 3 or a valence lower than that of a comparable phosphoric compound.
 in postmenopausal post·men·o·paus·al
adj.
Of or occurring in the time following menopause.


postmenopausal Change of life Gynecology adjective Referring to the time in ♀ when menstrual periods stop for ≥ 1 yr
 women."

Mr. Minton continued, "Of course, the success of this program cannot be guaranteed. Several more years of clinical studies are needed before XOSTEN can be registered and before it can demonstrate the medical and economic values needed to be competitive in the pharmaceutical markets of the future. However, we believe that XOSTEN will ultimately provide a vehicle for delivering an inherently safe, natural substance for effective long-term prevention and treatment of these two serious chronic diseases."

Church & Dwight Co., Inc. is the producer of ARM & HAMMER(R) brand household and personal products, and is the world's largest producer of U.S.P. sodium bicarbonate, potassium bicarbonate and related products.

CONTACT: Anthony P. Deasey

Church & Dwight Co., Inc.

(609) 683-7069
COPYRIGHT 1995 Business Wire
No portion of this article can be reproduced without the express written permission from the copyright holder.
Copyright 1995, Gale Group. All rights reserved. Gale Group is a Thomson Corporation Company.

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Publication:Business Wire
Date:Sep 12, 1995
Words:400
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