Chronimed Appoints Patricia Wetzel, M.D., to Position of Medical Director.

Business Editors/Health/Medical Writers

MINNEAPOLIS--(BUSINESS WIRE)--Oct. 16, 2003

Chronimed Inc., (Nasdaq:CHMD), today announced that Patricia Wetzel, M.D. has joined the Company as its Medical Director. In this new and important position, Dr. Wetzel will provide clinical leadership across all of the Company's business units, with particular emphasis on Chronimed's HIV endeavors.

"We are fortunate to have Patti join us as our medical director. Her 12 years of clinical experience, especially in HIV/AIDS medicine will be an extremely valuable addition to our disease management services," said Henry Blissenbach, President and Chief Executive Officer of Chronimed.

Dr. Wetzel received her medical degree from Northwestern University Medical School, Chicago, IL, and completed a family practice residency at John Peter Smith Hospital in Forth Worth, Texas. She served as a faculty member at the University of Texas Southwestern Medical School and Director of HIV Services at John Peter Smith Hospital in Forth Worth, after which she worked for Caremark, Inc. as their HIV program manager.

Her most recent positions include Associate Faculty, Department of Medical Humanities and Ethics at the University of Texas Health Science Center San Antonio. Dr. Wetzel has received numerous awards and distinctions including the "Face of Hope" Distinguished American Award, presented to her by President Clinton; and the Administrator's Citation from the U.S. Department of Health and Human Services.

About Chronimed Inc.

Chronimed Inc. is a disease-focused drug distribution company serving the prescription drug needs of people with chronic health conditions. The Company distributes pharmaceuticals and provides specialized patient management services nationwide for people with chronic conditions such as HIV/AIDS, organ transplant and diseases treated with biotech injectable medications. Chronimed works directly with patients, providers, payors, manufacturers and wholesalers to improve clinical and cost-of-care outcomes. Chronimed's web site address is www.chronimed.com.

Information contained in this press release and associated schedules, other than historical or current facts, should be considered forward-looking statements as defined in the Private Securities Litigation Reform Act of 1995. These statements reflect management's current views of future events and financial performance that involve a number of risks and uncertainties. These factors include, but are not limited to, the following: our ability to maintain satisfactory on-going arrangements with drug manufacturers and wholesalers, and their ability to satisfy our volume, pricing, and product requirements; decrease in demand for drugs we handle; changes in Medicare or Medicaid reimbursement, rules and regulations; loss of relationships with, and/or significant reductions in reimbursements from, payors (including Aetna or other large contracts); negative cost containment trends or financial difficulties by our payors; changes in or unknown violations of various federal, state, and local regulations; costs and other effects of legal or administrative proceedings; the adoption of new or changes to existing accounting policies and practices and the application of such policies and practices; the amount and rate of growth in our selling, general and administrative expenses; the impairment of a significant amount of our goodwill; the effects of and changes in, trade, monetary and fiscal policies, laws and regulations; other activities of government agencies; our ability to obtain competitive financing to fund operations and growth; continuing qualifications to list our securities on a national stock exchange; developments in medical research affecting the treatment or cure of conditions for which we distribute medications; the ability of management and accounting controls to assure accurate and timely information; computer system, software, or hardware failures or malfunctions; heightened competition; and loss or retirement of key executives or changes in ownership. These and other risks and uncertainties are discussed in further detail in the cautionary statement filed as Exhibit 99.1 as part of Chronimed's annual report and Form 10-K filed with the Securities and Exchange Commission.