Chromium plus vitamins C & E decrease insulin resistance in diabetes.The nutrient chromium, alone or in combination with vitamins C and E, significantly lessens oxidative stress oxidative stress, n an imbalance of the prooxidant antioxidant ratio in which too few antioxidants are produced or ingested or too many oxidizing agents are produced. and reduces insulin resistance Insulin Resistance Definition Insulin resistance is not a disease as such but rather a state or condition in which a person's body tissues have a lowered level of response to insulin, a hormone secreted by the pancreas that helps to regulate the level among patients with type 2 diabetes type 2 diabetes n. See diabetes mellitus. , according to the results of a new controlled study. * Thirty subjects were blindly and randomly assigned to receive one of three regimens: chromium (1,000 mcg); chromium plus vitamin C (1,000 mg) and vitamin E (800 IU); or inactive placebo; each day for six months. At baseline, the subjects' blood chromium levels and antioxidant antioxidant, substance that prevents or slows the breakdown of another substance by oxygen. Synthetic and natural antioxidants are used to slow the deterioration of gasoline and rubber, and such antioxidants as vitamin C (ascorbic acid), butylated hydroxytoluene status were measured. No significant differences were detected among the groups. But after half a year of supplementation, subjects taking chromium alone or chromium in combination with vitamin C and E experienced significantly improved antioxidant status and significantly reduced insulin resistance, fasting glucose, and hemoglobin A1c levels than subjects taking placebo. "These findings suggest that chromium supplementation alone and [the combination] of chromium together with vitamins C and E was effective for minimization of oxidative stress and improvement of glucose metabolism in type 2 [diabetes] patients," concluded the study's author. Reference * Lai MH. Antioxidant effects and insulin resistance improvement of chromium combined with vitamin C and E supplementation for type 2 diabetes mellitus Type 2 diabetes mellitus One of the two major types of diabetes mellitus, characterized by late age of onset (30 years or older), insulin resistance, high levels of blood sugar, and little or no need for supple-mental insulin. . J Clin Biochem Nutr. 2008 Nov;43(3):191-8. |
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