Printer Friendly
The Free Library
14,504,174 articles and books
Member login
User name  
Password 
 
Join us Forgot password?

Chiron Recalls and Withdraws MORUPAR(R) MMR Vaccine from Italian and Developing World Markets -- Chiron Also Revises 2005 Adjusted EPS From $1.34 to $1.31 Per Share and GAAP EPS From $0.97 to $0.94 Per Share.


EMERYVILLE, Calif. -- Chiron Corporation Chiron Corporation was a multinational biotechnology firm based in Emeryville, California that was acquired by Novartis International AG on April 20 2006. It had offices and facilities in eighteen countries on five continents.  (NASDAQ NASDAQ
 in full National Association of Securities Dealers Automated Quotations

U.S. market for over-the-counter securities. Established in 1971 by the National Association of Securities Dealers (NASD), NASDAQ is an automated quotation system that reports on
: CHIR CHIR Chiricahua National Monument (US National Park Service) ) today announced that it is recalling and withdrawing withdrawing Child psychiatry Behavior characterized by ↓ interest in or contact with other people; WBs include ↓ speech, regression to babyhood, exhibition of many fears, depression, refusing contact with other people  its measles measles or rubeola (rbē`ələ), highly contagious disease of young children, caused by a filterable virus and spread by droplet spray from the nose, mouth, , mumps and rubella rubella or German measles, acute infectious disease of children and young adults. It is caused by a filterable virus that is spread by droplet spray from the respiratory tract of an infected individual.  (MMR MMR measles-mumps-rubella (vaccine); see measles, mumps, and rubella vaccine live, under vaccine.

MMR
abbr.
measles, mumps, rubella vaccine
) vaccine vaccine

Preparation containing either killed or weakened live microorganisms or their toxins, introduced by mouth, by injection, or by nasal spray to stimulate production of antibodies against an infectious agent.
, MORUPAR(R). Chiron Chiron (kī`rŏn), in Greek mythology, centaur, son of Kronos. He was a renowned sage, physician, and prophet. Among his pupils were Hercules, Achilles, Jason, and Asclepius.  supplied approximately ap·prox·i·mate  
adj.
1. Almost exact or correct: the approximate time of the accident.

2.
 5 million doses of MORUPAR vaccine in 2005, providing most of its production to a limited number of developing countries, largely via the United Nations Children's Fund United Nations Children's Fund (UNICEF), an affiliated agency of the United Nations. It was established in 1946 as the United Nations International Children's Emergency Fund.  (UNICEF UNICEF (y`nĭsĕf'), the United Nations Children's Fund, an affiliated agency of the United Nations. ) and the Pan American Health Organization The Pan American Health Organization (PAHO) is an international public health agency with 100 years of experience in working to improve health and living standards of the countries of the Americas. It serves as the specialized organization for health of the Inter-American System.  (PAHO PAHO Pan American Health Organization (WHO) ), and approximately 450,000 doses to Italy Italy (ĭt`əlē), Ital. Italia, officially Italian Republic, republic (2005 est. pop. 58,103,000), 116,303 sq mi (301,225 sq km), S Europe. .

The results of routine pharmacovigilance pharmacovigilance,
n the monitoring of adverse effects of drugs and herbal remedies as they are used in the population. Also called
postmarketing surveillance.
 surveillance in Italy suggest that MORUPAR vaccine may be associated with a higher reported rate of adverse events following immunization immunization: see immunity; vaccination.  than other MMR vaccine MMR vaccine Live measles-mumps-rubella vaccine A trivalent vaccine containing an aqueous suspension of live attenuated strains of measles, mumps, and rubella viruses grown in chick or duck embryo cells. See Killed vaccine, Live attenuated vaccine.  products. While recent and historical surveillance data indicate that adverse events remain rare, Chiron is recalling and withdrawing the vaccine as a precautionary pre·cau·tion·ar·y   also pre·cau·tion·al
adj.
Of, relating to, or constituting a precaution: taking precautionary measures; gave precautionary advice.

Adj. 1.
 measure. Pharmacovigilance results suggest that these adverse events occurred post-immunization and do not indicate any long-term Long-term

Three or more years. In the context of accounting, more than 1 year.


long-term

1. Of or relating to a gain or loss in the value of a security that has been held over a specific length of time. Compare short-term.
 risk for patients who have previously received the vaccine. The adverse events on which the recall and withdrawal are based are within a range of those commonly associated with vaccines, such as fever, allergic reactions allergic reaction
n.
A local or generalized reaction of an organism to internal or external contact with a specific allergen to which the organism has been previously sensitized.
 and swelling swelling /swell·ing/ (swel´ing)
1. transient abnormal enlargement of a body part or area not due to cell proliferation.

2. an eminence, or elevation.
 of the glands.

Chiron has been in communication with the relevant health authorities and informed them of its actions in order to enable them to find replacement supplies of MMR vaccine. Chiron will work closely with the World Health Organization (WHO) to assist it in conducting a thorough risk-benefit analysis risk-benefit analysis,
n the consideration as to whether a medical or surgical procedure, particuarly a radical approach, is worth the risk to the patient compared with the possible benefits if the procedure is successful.
 of MORUPAR vaccine to determine whether it is appropriate for a limited quantity of the existing inventory to remain available for current public health programs such as those conducted by UNICEF and PAHO.

In 2005, Chiron's sales of MORUPAR vaccine totaled approximately $10 million. As a result of this recall and withdrawal, as well as other adjustments identified by Chiron and recorded subsequent to the company's January January: see month.  31, 2006, announcement of fourth-quarter and year-end year-end also year·end
n.
The end of a year.

adj.
Occurring or done at the end of the year: a year-end audit.

Noun 1.
 2005 financial results, Chiron has revised its 2005 earnings per share to $1.31 on an adjusted basis and $0.94 on a GAAP GAAP

See: Generally Accepted Accounting Principles


GAAP

See generally accepted accounting principles (GAAP).
 basis. Chiron has written off approximately $6.0 million of MORUPAR inventory in 2005 as a result of the withdrawal and has recorded approximately $1.7 million of product returns reserves in 2005 in connection with expected returns Expected Return

The average of a probability distribution of possible returns, calculated by using the following formula:
 of 2005 product sales from the recall. The recall and withdrawal of MORUPAR, which Chiron produces in Italy, does not affect any of Chiron's other vaccines.

Revised Year-End December December: see month.  31, 2005, Financial Results

For the year ended December 31, 2005, on an adjusted basis, Chiron reported revised income from continuing operations continuing operations

Parts of a business that are expected to be maintained as an ongoing segment of an overall business operation. Income and losses from continuing operations are reported separately if any segments have been discontinued during the
 of $253 million, or $1.31 per share, a decrease of $0.03 per share from financial results as reported on January 31, 2006. On a GAAP basis, Chiron reported revised income from continuing operations of $180 million, or $0.94 per share, a decrease of $0.03 per share from financial results as reported on January 31, 2006.

Revised Fourth-Quarter 2005 Financial Results

For the fourth quarter of 2005, on an adjusted basis, Chiron reported revised income from continuing operations of $158 million, or $0.78 per share, a decrease of $0.03 per share from financial results as reported on January 31, 2006. On a GAAP basis, Chiron reported revised income from continuing operations of $138 million, or $0.68 per share, a decrease of $0.03 per share from financial results as reported on January 31, 2006.

Chiron uses adjusted financial information to gain an understanding of the company's operating performance on a comparative basis. Adjusted amounts exclude special items relating to relating to relate prepconcernant

relating to relate prepbezüglich +gen, mit Bezug auf +acc 
 certain acquisitions and impairment Impairment

1. A reduction in a company's stated capital.

2. The total capital that is less than the par value of the company's capital stock.

Notes:
1. This is usually reduced because of poorly estimated losses or gains.

2.
 losses on acquired intangible assets Intangible Asset

An asset that is not physical in nature.

Notes:
Examples are things like copyrights, patents, intellectual property, and goodwill. These are the opposite of tangible assets.
, which may not be indicative indicative: see mood.  of the company's trends or potential future performance. Please refer to the tables at the end of this press release for more detail on these items and a reconciliation of the adjusted financial information to GAAP financial information; this information is also located at www.chiron.com in the Investors section under Financial Reports. All references to per-share amounts are per diluted di·lute  
tr.v. di·lut·ed, di·lut·ing, di·lutes
1. To make thinner or less concentrated by adding a liquid such as water.

2. To lessen the force, strength, purity, or brilliance of, especially by admixture.
 share.

About Chiron

Chiron delivers innovative and valuable products to protect human health by advancing pioneering science across the landscape of biotechnology biotechnology, the use of biological processes, as through the exploitation and manipulation of living organisms or biological systems, in the development or manufacture of a product or in the technological solution to a problem. . The company works to deliver on the limitless promise of science and make a positive difference in people's lives. For more information, please visit www.chiron.com.

Revised Financial Information

2005 financial information in PDF (Portable Document Format) The de facto standard for document publishing from Adobe. On the Web, there are countless brochures, data sheets, white papers and technical manuals in the PDF format.  format

http://www.chiron.com/investors/2389/chiron_financial.pdf

2005 financial information online

http://www.chiron.com/investors/finreports/index.html

This news release contains forward-looking statements forward-looking statement

A projected financial statement based on management expectations. A forward-looking statement involves risks with regard to the accuracy of assumptions underlying the projections.
, including statements regarding expected financial results for 2005 and the impact of the recall and withdrawal of MORUPAR MMR vaccine on Chiron's business, which involve risks and uncertainties and are subject to change. A discussion of the company's operations and financial condition, including factors that may affect its business and future prospects that could cause actual results and developments to differ materially from those expressed or implied Inferred from circumstances; known indirectly.

In its legal application, the term implied is used in contrast with express, where the intention regarding the subject matter is explicitly and directly indicated.
 by these forward-looking statements, is contained in documents the company has filed with the SEC, including the Form 10-K Form 10-K

A report required by the SEC from exchange-listed companies that provides for annual disclosure of certain financial information.


Form 10-K

See 10-K.
 for the year ended December 31, 2004, and the Form 10-Q Form 10-Q

See 10-Q.
 for the quarter ended September September: see month.  30, 2005, and will be contained in all subsequent periodic filings made with the SEC. These documents identify important factors that could cause the company's actual performance to differ from current expectations, including, among others, litigation An action brought in court to enforce a particular right. The act or process of bringing a lawsuit in and of itself; a judicial contest; any dispute.

When a person begins a civil lawsuit, the person enters into a process called litigation.
 and investigations relating to influenza vaccines influenza vaccine Flu vaccine A vaccine recommended for those at high risk for serious complications from influenza: > age 65; Pts with chronic diseases of heart, lung or kidneys, DM, immunosuppression, severe anemia, nursing home and other chronic-care , the outcome of clinical trials, regulatory reg·u·late  
tr.v. reg·u·lat·ed, reg·u·lat·ing, reg·u·lates
1. To control or direct according to rule, principle, or law.

2.
 review and approvals, manufacturing capabilities, intellectual property protections and defenses, litigation, product liability claims, stock-price and interest-rate volatility Volatility

1. A statistical measure of the tendency of a market or security to rise or fall sharply within a period of time.

2. A variable in option pricing formulas that denotes the extent to which the return of the underlying asset will fluctuate between now and the
, and marketing effectiveness Marketing Effectiveness is the function of improving how marketers go to market with the goal of optimizing their marketing spend to achieve even better results for both the short-term and long-term. Also related to Marketing ROI and Return on Marketing Investment (ROMI). . In particular, there can be no assurance that financial results for 2005 will be the same as preliminary results Chiron has announced today or that Chiron will be able to successfully develop and receive approval to market new products. In addition, the company may engage in business opportunities, the successful completion of which is subject to certain risks, including approval by Novartis AG Novartis AG

Swiss pharmaceutical company. It was formed through the 1996 merger of two Swiss firms: Ciba (see Ciba-Geigy) and Sandoz, a chemical company with interests in pharmaceuticals, nutrition, and agriculture.
, regulatory approvals and the integration of operations.

Chiron does not undertake an obligation to update the forward-looking for·ward-look·ing
adj.
Concerned with or making provision for the future: forward-looking educators; a forward-looking corporate plan.

Adj. 1.
 information the company is giving today. Financial results for 2005 included in this press release are preliminary.
CHIRON CORPORATION
CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS
(Unaudited)
(In thousands, except per share data)


                                  Three Months Ended
                                     December 31,
                 -----------------------------------------------------
                           2005                       2004
                 -------------------------- --------------------------
                 Adjusted Adjust-  Actual   Adjusted Adjust-  Actual
                    (1)    ments               (2)    ments
                 -------- ------- --------  -------- ------- ---------

Revenues:
  Product sales,
   net           $473,581      $- $473,581  $330,467      $- $330,467
  Revenues from
   joint business
   arrangement     33,547       -   33,547    25,336       -   25,336
  Collaborative
   agreement
   revenues         1,955       -    1,955     3,577       -    3,577
  Royalty and
   license fee
   revenues        89,697       -   89,697    68,177       -   68,177
  Other revenues   15,173       -   15,173     6,838       -    6,838
                 -------- ------- --------  -------- ------- ---------

      Total
       revenues   613,953       -  613,953   434,395       -  434,395
                 -------- ------- --------  -------- ------- ---------

Operating
 expenses:
  Cost of sales   221,095       -  221,095   177,136       -  177,136
  Research and
   development    109,271       -  109,271   129,392       -  129,392
  Selling,
   general and
   administrative 125,391       -  125,391   137,727       -  137,727
  Amortization
   expense              - (11,969)  11,969         - (21,426)  21,426
  Impairment loss
   on acquired
   intangible
   assets               -  (1,136)   1,136         -       -        -
  Other operating
   expenses         7,692       -    7,692     4,804       -    4,804
                 -------- ------- --------  -------- ------- ---------

      Total
       operating
       expenses   463,449 (13,105) 476,554   449,059 (21,426) 470,485
                 -------- ------- --------  -------- ------- ---------

Income (loss)
 from operations  150,504  13,105  137,399   (14,664) 21,426  (36,090)


Loss on disposal
 of assets           (319)      -     (319)   (2,092)      -   (2,092)
Interest expense   (7,683)      -   (7,683)   (6,653)      -   (6,653)
Interest and
 other income,
 net               19,644       -   19,644    14,390       -   14,390
Minority interest    (498)      -     (498)     (385)      -     (385)
                 -------- ------- --------  -------- ------- ---------

Income (loss)
 from continuing
 operations
 before income
 taxes            161,648  13,105  148,543    (9,404) 21,426  (30,830)

Provision for
 (benefit of)
 income taxes       3,806  (6,685)  10,491    (2,351)  5,356   (7,707)
                 -------- ------- --------  -------- ------- ---------

Income (loss)
 from continuing
 operations       157,842  19,790  138,052    (7,053) 16,070  (23,123)
                 ======== ======= ========  ======== ======= =========

Net income (loss)$157,842 $19,790 $138,052   $(7,053)$16,070 $(23,123)
                 ======== ======= ========  ======== ======= =========

Basic earnings
 (loss) per
 share:
   Income (loss)
    from
    continuing
    operations      $0.83            $0.72    $(0.04)          $(0.12)
                 ========         ========  ========         =========
   Net income
    (loss)          $0.83            $0.72    $(0.04)          $(0.12)
                 ========         ========  ========         =========

Diluted earnings
 (loss) per
 share:
   Income (loss)
    from
    continuing
    operations      $0.78            $0.68    $(0.04)          $(0.12)
                 ========         ========  ========         =========
   Net income
    (loss)          $0.78            $0.68    $(0.04)          $(0.12)
                 ========         ========  ========         =========


Shares used in
 calculating
 basic earnings
 (loss) per share 190,679          190,679   186,813          186,813
                 ========         ========  ========         =========

Shares used in
 calculating
 diluted earnings
 (loss) per share 205,008          205,008   186,813          186,813
                 ========         ========  ========         =========


(1) Adjusted amounts exclude (a) the amortization expense on acquired
    intangible assets related to the acquisitions of PathoGenesis,
    Chiron Behring, Pulmopharm and PowderJect Pharmaceuticals and (b)
    an impairment loss of $1.1 million on acquired intangible assets
    from our acquisition of PowderJect Pharmaceuticals related to a
    contract manufacturing agreement.

(2) Adjusted amounts exclude the amortization expense on acquired
    intangible assets related to the acquisitions of PathoGenesis,
    Chiron Behring, Pulmopharm and PowderJect Pharmaceuticals.



CHIRON CORPORATION
CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS
(Unaudited)
(In thousands, except per share data)


                                                Year Ended
                                               December 31,
                                     ---------------------------------
                                                   2005
                                     ---------------------------------
                                      Adjusted Adjustments   Actual
                                         (3)
                                     ---------- ---------- -----------

Revenues:
  Product sales, net                 $1,421,494         $- $1,421,494
  Revenues from joint business
   arrangement                          136,701          -    136,701
  Collaborative agreement revenues       13,084          -     13,084
  Royalty and license fee revenues      317,006          -    317,006
  Other revenues                         31,394          -     31,394
                                     ---------- ---------- -----------

      Total revenues                  1,919,679          -  1,919,679
                                     ---------- ---------- -----------

Operating expenses:
  Cost of sales                         732,100          -    732,100
  Research and development              433,891          -    433,891
  Selling, general and administrative   501,193          -    501,193
  Purchased in-process research and
   development                                -          -          -
  Amortization expense                        -    (66,206)    66,206
  Impairment loss on acquired
   intangible assets                          -    (15,658)    15,658
  Other operating expenses               20,515          -     20,515
                                     ---------- ---------- -----------

      Total operating expenses        1,687,699    (81,864) 1,769,563
                                     ---------- ---------- -----------

Income from operations                  231,980     81,864    150,116


Loss on disposal of assets               (1,108)         -     (1,108)
Interest expense                        (30,615)         -    (30,615)
Interest and other income, net           86,692          -     86,692
Minority interest                        (2,221)         -     (2,221)
                                     ---------- ---------- -----------

Income from continuing operations
 before income taxes                    284,728     81,864    202,864

Provision for income taxes               31,431      9,037     22,394
                                     ---------- ---------- -----------

Income from continuing operations       253,297     72,827    180,470
                                     ========== ========== ===========

Gain from discontinued operations,
 net of taxes                                 -          -          -
                                     ---------- ---------- -----------

Net income                             $253,297    $72,827   $180,470
                                     ========== ========== ===========

Basic earnings per share:
   Income from continuing operations      $1.34                 $0.96
                                     ==========            ===========
   Net income                             $1.34                 $0.96
                                     ==========            ===========

Diluted earnings per share:
   Income from continuing operations      $1.31                 $0.94
                                     ==========            ===========
   Net income                             $1.31                 $0.94
                                     ==========            ===========


Shares used in calculating basic
 earnings per share                     188,448               188,448
                                     ==========            ===========

Shares used in calculating diluted
 earnings per share                     199,280               198,704
                                     ==========            ===========



                                                Year Ended
                                               December 31,
                                    ----------------------------------
                                                   2004
                                     ---------------------------------
                                      Adjusted  Adjustments  Actual
                                         (4)
                                     ---------------------------------

Revenues:
  Product sales, net                 $1,268,303         $- $1,268,303
  Revenues from joint business
   arrangement                          118,246          -    118,246
  Collaborative agreement revenues       18,044          -     18,044
  Royalty and license fee revenues      289,561          -    289,561
  Other revenues                         29,201          -     29,201
                                     ---------- ---------- -----------

      Total revenues                  1,723,355          -  1,723,355
                                     ---------- ---------- -----------

Operating expenses:
  Cost of sales                         675,944          -    675,944
  Research and development              431,128          -    431,128
  Selling, general and
   administrative                       459,502          -    459,502
  Purchased in-process research and
   development                                -     (9,629)     9,629
  Amortization expense                        -    (84,503)    84,503
  Impairment loss on acquired
   intangible assets                          -          -          -
  Other operating expenses               12,844          -     12,844
                                     ---------- ---------- -----------

      Total operating expenses        1,579,418    (94,132) 1,673,550
                                     ---------- ---------- -----------

Income from operations                  143,937     94,132     49,805


Loss on disposal of assets               (3,247)         -     (3,247)
Interest expense                        (26,093)         -    (26,093)
Interest and other income, net           56,797          -     56,797
Minority interest                        (1,968)         -     (1,968)
                                     ---------- ---------- -----------

Income from continuing operations
 before income taxes                    169,426     94,132     75,294

Provision for income taxes               42,357     21,126     21,231
                                     ---------- ---------- -----------

Income from continuing operations       127,069     73,006     54,063
                                     ========== ========== ===========

Gain from discontinued operations,
 net of taxes                            24,854          -     24,854
                                     ---------- ---------- -----------

Net income                             $151,923    $73,006    $78,917
                                     ========== ========== ===========

Basic earnings per share:
   Income from continuing operations      $0.68                 $0.29
                                     ==========            ===========
   Net income                             $0.81                 $0.42
                                     ==========            ===========

Diluted earnings per share:
   Income from continuing operations      $0.67                 $0.28
                                     ==========            ===========
   Net income                             $0.80                 $0.41
                                     ==========            ===========


Shares used in calculating basic
 earnings per share                     187,545               187,545
                                     ==========            ===========

Shares used in calculating diluted
 earnings per share                     190,202               190,202
                                     ==========            ===========


(3) Adjusted amounts exclude (a) the amortization expense on acquired
    intangible assets related to the acquisitions of PathoGenesis,
    Chiron Behring, Pulmopharm and PowderJect Pharmaceuticals, (b) an
    impairment loss of $14.5 million on acquired intangible assets
    from our acquisition of PowderJect Pharmaceuticals related to a
    yellow fever vaccine and (c) an impairment loss of $1.1 million on
    acquired intangible assets from our acquisition of PowderJect
    Pharmaceuticals related to a contract manufacturing agreement.

(4) Adjusted amounts exclude (a) the amortization expense on acquired
    intangible assets related to the acquisitions of PathoGenesis,
    Chiron Behring, Pulmopharm and PowderJect Pharmaceuticals and (b)
    Purchased in-process research and development related to the
    Sagres acquisition.



CHIRON CORPORATION
CONDENSED CONSOLIDATED BALANCE SHEETS
(Unaudited)
(In thousands)


                                                December    December
                                                   31,         31,
                                                  2005        2004
                                               ----------- -----------

                    Assets
                    ------
Current assets:
    Cash, cash equivalents and short-term
     investments                                 $686,074    $603,621
    Accounts receivable, net of allowances        475,718     402,094
    Inventories, net of reserves                  231,666     221,154
    Other current assets                          198,394     167,154
                                               ----------- -----------
        Total current assets                    1,591,852   1,394,023
Non-current investments in marketable debt
 securities                                       722,717     409,421
Property, plant, equipment and leasehold
 improvements, net                                888,803     799,415
Other non-current assets                        1,544,107   1,702,644
                                               ----------- -----------
            Total assets                       $4,747,479  $4,305,503
                                               =========== ===========

     Liabilities and stockholders' equity
     ------------------------------------
Current liabilities                              $564,764    $434,444
Long-term debt                                    890,945     936,652
Long-term portion of capital lease                156,661     156,952
Non-current unearned revenue                       27,359      26,175
Other non-current liabilities                     112,828     140,226
Minority interest                                  10,779       9,350
Stockholders' equity                            2,984,143   2,601,704
                                               ----------- -----------
            Total liabilities and
             stockholders' equity              $4,747,479  $4,305,503
                                               =========== ===========



CHIRON CORPORATION
SUPPLEMENTAL SCHEDULE OF COMPUTATION OF EARNINGS (LOSS) PER SHARE
(Unaudited)
(In thousands, except per share data)

                                          Three Months Ended
                                             December 31,
                                       2005               2004
                                ------------------- ------------------
                                Adjusted   Actual   Adjusted  Actual
                                --------- --------- -------- ---------

Computation for earnings (loss)
 per share - continuing
 operations
Income (loss) (Numerator):
  Income (loss) from continuing
   operations                   $157,842  $138,052  $(7,053) $(23,123)
  Plus: Interest on 1.625%
   convertible debentures, net
   of taxes                        1,586     1,586        -         -
  Plus: Interest on Liquid
   Yield Option Notes, net of
   taxes                             147       147        -         -
                                --------- --------- -------- ---------
  Income (loss) from continuing
   operations, plus impact from
   assumed conversions          $159,575  $139,785  $(7,053) $(23,123)
                                ======================================

Shares (Denominator):
    Weighted-average common
     shares outstanding          190,679   190,679  186,813   186,813
    Additional shares from
     exercise of right under an
     agreement with Novartis (5)   3,448     3,448        -         -
Effect of dilutive securities:
    Stock options and
     equivalents                   3,001     3,001        -         -
    1.625% convertible
     debentures                    7,306     7,306        -         -
    Liquid Yield Option Notes        574       574        -         -
                                --------- --------- -------- ---------
    Weighted-average common
     shares outstanding, plus
     impact from assumed
     conversions                 205,008   205,008  186,813   186,813
                                ======================================


Basic earnings (loss) per share
 from continuing operations        $0.83     $0.72   $(0.04)   $(0.12)
                                ========= ========= ======== =========
Diluted earnings (loss) per
 share from continuing
 operations                        $0.78     $0.68   $(0.04)   $(0.12)
                                ========= ========= ======== =========

Computation for earnings (loss)
 per share - net income (loss)
Income (loss) (Numerator):
  Net income (loss)             $157,842  $138,052  $(7,053) $(23,123)
  Plus: Interest on 1.625%
   convertible debentures, net
   of taxes                        1,586     1,586        -         -
  Plus: Interest on Liquid
   Yield Option Notes, net of
   taxes                             147       147        -         -
                                --------- --------- -------- ---------
  Net income (loss), plus
   impact from assumed
   conversions                  $159,575  $139,785  $(7,053) $(23,123)
                                ======================================

Shares (Denominator):
    Weighted-average common
     shares outstanding          190,679   190,679  186,813   186,813
    Additional shares from
     exercise of right under an
     agreement with Novartis (5)   3,448     3,448        -         -
Effect of dilutive securities:
    Stock options and
     equivalents                   3,001     3,001        -         -
    1.625% convertible
     debentures                    7,306     7,306        -         -
    Liquid Yield Option Notes        574       574        -         -
                                --------- --------- -------- ---------
    Weighted-average common
     shares outstanding, plus
     impact from assumed
     conversions                 205,008   205,008  186,813   186,813
                                ======================================


Basic earnings (loss) per share
 from net income                   $0.83     $0.72   $(0.04)   $(0.12)
                                ========= ========= ======== =========
Diluted earnings (loss) per
 share from net income             $0.78     $0.68   $(0.04)   $(0.12)
                                ========= ========= ======== =========


(5) On October 30, 2005 we exercised our right under an agreement with
    Novartis (as successor to Ciba-Geigy), dated as of November 20,
    1994, as amended, to require Novartis or its affiliate to purchase
    shares of our common stock for an aggregate purchase price of
    $300.0 million at a per share purchase price of $43.50. On
    December 8, 2005, we closed on a sale of $300.0 million in newly
    issued shares of our common stock at a price of $43.50 per share
    to a subsidiary of Novartis. For purposes of calculating diluted
    earnings per share, the issued shares of this transaction are
    considered outstanding from October 30, 2005. As a result, the
    calculation of diluted earnings per share for the fourth quarter
    of 2005 included an additional 3.4 million shares.



CHIRON CORPORATION
SUPPLEMENTAL SCHEDULE OF COMPUTATION OF EARNINGS PER SHARE
(Unaudited)
(In thousands, except per share data)

                                              Year Ended
                                             December 31,
                                       2005               2004
                                ------------------- ------------------
                                Adjusted   Actual   Adjusted   Actual
                                --------- --------- --------- --------

Computation for earnings per
 share - continuing operations
Income (Numerator):
  Income from continuing
   operations                   $253,297  $180,470  $127,069  $54,063
  Plus: Interest on 1.625%
   convertible debentures, net
   of taxes                        6,357     6,357         -        -
  Plus: Interest on Liquid
   Yield Option Notes, net of
   taxes                             586         -         -        -
                                --------- --------- --------- --------
  Income from continuing
   operations, plus impact from
   assumed conversions          $260,240  $186,827  $127,069  $54,063
                                ======================================

Shares (Denominator):
    Weighted-average common
     shares outstanding          188,448   188,448   187,545  187,545
    Additional shares from
     exercise of right under an
     agreement with Novartis (6)   1,061     1,061         -        -
Effect of dilutive securities:
    Stock options and
     equivalents                   1,887     1,887     2,657    2,657
    1.625% convertible
     debentures                    7,308     7,308         -        -
    Liquid Yield Option Notes        576         -         -        -
                                --------- --------- --------- --------
    Weighted-average common
     shares outstanding, plus
     impact from assumed
     conversions                 199,280   198,704   190,202  190,202
                                ======================================


Basic earnings per share from
 continuing operations             $1.34     $0.96     $0.68    $0.29
                                ========= ========= ========= ========
Diluted earnings per share from
 continuing operations             $1.31     $0.94     $0.67    $0.28
                                ========= ========= ========= ========

Computation for earnings per
 share - net income
Income (Numerator):
  Net income                    $253,297  $180,470  $151,923  $78,917
  Plus: Interest on 1.625%
   convertible debentures, net
   of taxes                        6,357     6,357         -        -
  Plus: Interest on Liquid
   Yield Option Notes, net of
   taxes                             586         -         -        -
                                --------- --------- --------- --------
  Net income, plus impact from
   assumed conversions          $260,240  $186,827  $151,923  $78,917
                                ======================================

Shares (Denominator):
    Weighted-average common
     shares outstanding          188,448   188,448   187,545  187,545
    Additional shares from
     exercise of right under an
     agreement with Novartis (6)   1,061     1,061         -        -
Effect of dilutive securities:
    Stock options and
     equivalents                   1,887     1,887     2,657    2,657
    1.625% convertible
     debentures                    7,308     7,308         -        -
    Liquid Yield Option Notes        576         -         -        -
                                --------- --------- --------- --------
    Weighted-average common
     shares outstanding, plus
     impact from assumed
     conversions                 199,280   198,704   190,202  190,202
                                ======================================


Basic earnings per share from
 net income                        $1.34     $0.96     $0.81    $0.42
                                ========= ========= ========= ========
Diluted earnings per share from
 net income                        $1.31     $0.94     $0.80    $0.41
                                ========= ========= ========= ========


(6) On October 30, 2005, we exercised our right under an agreement
    with Novartis (as successor to Ciba-Geigy), dated as of November
    20, 1994, as amended, to require Novartis or its affiliate to
    purchase shares of our common stock for an aggregate purchase
    price of $300.0 million at a per share purchase price of $43.50.
    On December 8, 2005, we closed on a sale of $300.0 million in
    newly issued shares of our common stock at a price of $43.50 per
    share to a subsidiary of Novartis. For purposes of calculating
    diluted earnings per share, the issued shares of this transaction
    are considered outstanding from October 30, 2005. As a result, the
    calculation of diluted earnings per share for the year included an
    additional 1.1 million shares.



CHIRON CORPORATION
SUPPLEMENTAL REVENUE SUMMARY
(Unaudited)
(In thousands, except percentages)


                                      Current  Prior   Change
                                      Quarter Quarter   from    Change
                                      Q4 2005 Q3 2005 Prior QTR   %
                                     ---------------------------------
Product Sales
 Blood Testing
    Ortho                              $9,825   $7,023   $2,802    40%
    NAT                                72,195   70,677    1,518     2%
                                     ---------------------------------
 Total Blood Testing                   82,020   77,700    4,320     6%

Vaccines
   Influenza vaccines                 161,955   60,321  101,634   168%
   Meningococcal vaccines               8,968   11,635   (2,667) (23)%
   Travel vaccines (TBE, Rabies,
    Arilvax and Dukoral)               23,722   35,012  (11,290) (32)%
   Pediatric/Other vaccines            48,888   45,800    3,088     7%
                                     ---------------------------------
 Total Vaccines                       243,533  152,768   90,765    59%

Biopharmaceuticals
  Proleukin                            31,259   31,028      231     1%
  TOBI                                 65,199   57,890    7,309    13%
  Betaseron(a)                         40,545   36,927    3,618    10%
  Other                                11,025   10,862      163     2%
                                     ---------------------------------
Total Biopharmaceuticals              148,028  136,707   11,321     8%

 TOTAL PRODUCT SALES, NET            $473,581 $367,175 $106,406    29%
                                     =================================


Revenues from joint business
 arrangement                          $33,547  $36,093  $(2,546)  (7)%
Collaborative agreement revenues        1,955    3,149   (1,194) (38)%
Royalty and license fee revenues       89,697   70,726   18,971    27%
Other revenues                         15,173    2,470   12,703   514%
                                     ---------------------------------
  TOTAL REVENUES                     $613,953 $479,613 $134,340    28%
                                     =================================

Gross Margins
Blood Testing                              38%      42%     (4)%
Vaccines                                   45%      45%       0%
Biopharmaceuticals                         76%      71%       5%
                                     ---------------------------
  TOTAL GROSS MARGINS                      53%      54%     (1)%
                                     ===========================

----------------------------------------------------------------------
(a) Excludes Betaferon Royalty        $14,122  $13,413     $709     5%
----------------------------------------------------------------------


                                               Prior   Change
                                               Year     from   Change
                                              Q4 2004   Prior     %
                                                        Year
                                              ------------------------
Product Sales
 Blood Testing
    Ortho                                       $7,904   $1,921    24%
    NAT                                         63,705    8,490    13%
                                              ------------------------
 Total Blood Testing                            71,609   10,411    15%

Vaccines
   Influenza vaccines                           44,015  117,940   268%
   Meningococcal vaccines                        9,309     (341)  (4)%
   Travel vaccines (TBE, Rabies, Arilvax and
    Dukoral)                                    21,159    2,563    12%
   Pediatric/Other vaccines                     57,656   (8,768) (15)%
                                              ------------------------
 Total Vaccines                                132,139  111,394    84%

Biopharmaceuticals
  Proleukin                                     30,713      546     2%
  TOBI                                          53,276   11,923    22%
  Betaseron(a)                                  33,639    6,906    21%
  Other                                          9,091    1,934    21%
                                              ------------------------
Total Biopharmaceuticals                       126,719   21,309    17%

 TOTAL PRODUCT SALES, NET                     $330,467 $143,114    43%
                                              ========================


Revenues from joint business arrangement       $25,336   $8,211    32%
Collaborative agreement revenues                 3,577   (1,622) (45)%
Royalty and license fee revenues                68,177   21,520    32%
Other revenues                                   6,838    8,335   122%
                                              ------------------------
  TOTAL REVENUES                              $434,395 $179,558    41%
                                              ========================

Gross Margins
Blood Testing                                       40%     (2)%
Vaccines                                            28%      17%
Biopharmaceuticals                                  70%       6%
                                              ------------------
  TOTAL GROSS MARGINS                               46%       7%
                                              ==================

----------------------------------------------------------------------
(a) Excludes Betaferon Royalty                 $12,798   $1,324    10%
----------------------------------------------------------------------



CHIRON CORPORATION
SUPPLEMENTAL YTD REVENUE SUMMARY
(Unaudited)
(In thousands, except percentages)


                               Twelve Months Ended     Change   Change
                                    December 31,        from       %
                                                        Prior
                                 2005        2004       Year
                              ----------------------------------------
Product Sales
 Blood Testing
    Ortho                        $31,298     $27,844    $3,454     12%
    NAT                          273,407     249,809    23,598      9%
                              ----------------------------------------
 Total Blood Testing             304,705     277,653    27,052     10%

 Vaccines
   Influenza vaccines            225,355     153,413    71,942     47%
   Meningococcal vaccines         43,361      27,739    15,622     56%
   Travel vaccines (TBE,
    Rabies, Arilvax and
    Dukoral)                     147,507      96,864    50,643     52%
   Pediatric/Other vaccines      164,308     200,948   (36,640)  (18)%
                              ----------------------------------------
 Total Vaccines                  580,531     478,964   101,567     21%

Biopharmaceuticals
  Proleukin                      123,549     129,377    (5,828)   (5)%
  TOBI                           232,624     212,876    19,748      9%
  Betaseron(a)                   142,238     130,572    11,666      9%
  Other                           37,847      38,861    (1,014)   (3)%
                              ----------------------------------------
Total Biopharmaceuticals         536,258     511,686    24,572      5%

 TOTAL PRODUCT SALES, NET     $1,421,494  $1,268,303  $153,191     12%
                              ========================================


Revenues from joint business
 arrangement                    $136,701    $118,246   $18,455     16%
Collaborative agreement
 revenues                         13,084      18,044    (4,960)  (27)%
Royalty and license fee
 revenues                        317,006     289,561    27,445      9%
Other revenues                    31,394      29,201     2,193      8%
                              ----------------------------------------
   TOTAL REVENUES             $1,919,679  $1,723,355  $196,324     11%
                              ========================================

Gross Margins
Blood Testing                         41%         42%      (1)%
Vaccines                              31%         23%        8%
Biopharmaceuticals                    72%         72%        0%
                              ---------------------------------
   TOTAL GROSS MARGINS                48%         47%        1%
                              =================================

----------------------------------------------------------------------
(a) Excludes Betaferon Royalty   $59,955     $51,564    $8,391     16%
----------------------------------------------------------------------
COPYRIGHT 2006 Business Wire
No portion of this article can be reproduced without the express written permission from the copyright holder.
Copyright 2006, Gale Group. All rights reserved. Gale Group is a Thomson Corporation Company.

 Reader Opinion

Title:

Comment:



 

Article Details
Printer friendly Cite/link Email Feedback
Publication:Business Wire
Date:Mar 16, 2006
Words:3972
Previous Article:Pacific Sands, Inc. and Flexible Solutions, Inc. Enter Joint Product Development and Strategic Marketing Alliance.
Next Article:Rick Tumlinson Leads Keynote Series for 22nd Annual User2User Conference; Registration is Now Open.
Topics:



Related Articles
Chiron to Purchase Interest in Hoechst's Behringwerke Vaccine Business.
Chiron Renames Chiron Biocine Chiron Vaccines.
Chiron Behring Forms Marketing Agreement For Germany With North American Vaccine.
LION GETS NEW AND UPGRADED LICENSES FOR SRS.
Chiron Revises Full-Year 2004 Pro-Forma Earnings From 70 Cents to 67 Cents Per Share, GAAP Earnings From 32 Cents to 28 Cents Per Share.
Chiron Revises Production Range for FLUVIRIN Vaccine and Updates Financial Guidance; Delays in Reaching Full-Scale Production Expected to Reduce...
Chiron Reports Second-Quarter 2005 Adjusted Earnings of $0.08 Per Share, GAAP Earnings of Less Than $0.01 Per Share; 10 Percent Increase in Revenues...
Chiron Reports Third-Quarter 2005 Adjusted Earnings of $0.38 per Share, GAAP Earnings of $0.27 per Share.
Chiron Updates Delivery Expectations for U.S. Government H5N1 Vaccine Stockpile Contract.
CHIRON GETS PANDEMIC INFLUENZA VACCINE CONTRACT WITH U.K.

Terms of use | Copyright © 2009 Farlex, Inc. | Feedback | For webmasters | Submit articles