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Chicken eggs as drug factories.


Medicine comes in lots of different packages. Painkillers in a tablet See digitizer tablet and tablet computer.

TABLET - A query language.

["Human Factor Comparison of a Procedural and a Non-procedural Query Language", C. Welty et al, ACM Trans Database Sys 6(4):626-649 (Dec 1981)].
 can make your headache go away. Antibiotic antibiotic, any of a variety of substances, usually obtained from microorganisms, that inhibit the growth of or destroy certain other microorganisms. Types of Antibiotics
 cream from a tube can prevent your cuts from becoming infected in·fect  
tr.v. in·fect·ed, in·fect·ing, in·fects
1. To contaminate with a pathogenic microorganism or agent.

2. To communicate a pathogen or disease to.

3. To invade and produce infection in.
. But can medicine come packaged in chicken eggs?

A team of scientists from Scotland says yes. They've engineered special chickens that lay eggs with disease-treating drugs inside.

[ILLUSTRATION OMITTED]

These drugs are made of molecules called proteins. Animals make thousands of proteins--they're the main ingredient in skin, hair, milk, and meat. Since animals can make proteins easily, they're good candidates for making protein drugs.

Researchers have already made cows, sheep, and goats that pump out protein drugs in their milk. But chickens are cheaper to take care of, need less room, and grow faster than these other animals. Those qualities could make chickens a better choice to become living drug factories, says Simon Lillico of the Roslin Institute near Edinburgh, Scotland.

Lillico and a team of researchers changed chickens' DNA--the code that tells cells how to make proteins--so that the birds' cells made two protein drugs. One drug can treat skin cancer, and the other treats a nerve disease called multiple sclerosis multiple sclerosis (MS), chronic, slowly progressive autoimmune disease in which the body's immune system attacks the protective myelin sheaths that surround the nerve cells of the brain and spinal cord (a process called demyelination), resulting in damaged areas .

The scientists altered the chickens' DNA DNA: see nucleic acid.
DNA
 or deoxyribonucleic acid

One of two types of nucleic acid (the other is RNA); a complex organic compound found in all living cells and many viruses. It is the chemical substance of genes.
 so that the birds made these drugs only in their egg whites. This protects the chickens' bodies from the drugs' possible harmful effects and makes it easy for scientists to collect the drugs.

[ILLUSTRATION OMITTED]

These special chickens can pass on their drug-laying abilities to their chicks. So far, the Scottish researchers have bred five generations of drug-producing birds.

The scientists need to improve these chickens before they roost in drug companies' labs. The birds don't make enough drugs to treat people yet. But once the researchers perfect their technique, you might eventually take your medicine sunny-side up sun·ny-side up
adj.
Fried only on one side. Used of eggs.

Adj. 1. sunny-side up - (eggs) fried on only one side
cooked - having been prepared for eating by the application of heat
.--C. Brownlee
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Article Details
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Author:Brownlee, Christen
Publication:Science News for Kids
Geographic Code:4EUUK
Date:Jan 24, 2007
Words:297
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