Chemo-radiation combo may avert prostate cancer recurrence.Byline: ANI Washington, Nov 5 (ANI): Radiation therapy, in combination with chemotherapy before prostate removal, has been found safe for cancer patients and may reduce the risk of recurrence, say researchers. The research team from Oregon Health and Science University Knight Cancer Institute and the Portland Veterans Affairs Medical Centre has shown chemo-radiation combination is feasible and safe and improves survival among prostate cancer prostate cancer, cancer originating in the prostate gland. Prostate cancer is the leading malignancy in men in the United States and is second only to lung cancer as a cause of cancer death in men. patients. "In men with aggressive prostate cancer, standard therapies such as radiation or surgery often fail to eliminate the cancer completely at the site of treatment. When these cancers recur, they are often fatal," said Dr Mark Garzotto, principal investigator and Associate Professor of Urology and Radiation Medicine in the OHSU OHSU Oregon Health & Science University (Portland, OR, USA) Knight Cancer Institute; and Chief of Urologic Oncology in the Portland Veterans Affairs Medical Centre. "Novel approaches are needed if we are to make advances in this disease," he added. For the study, researchers developed a treatment regimen in which radiation and docetaxel were administered together before prostatectomy Prostatectomy Definition Prostatectomy refers to the surgical removal of part of the prostate gland (transurethral resection, a procedure performed to relieve urinary symptoms caused by benign enlargement), or all of the prostate (radical prostatectomy, . The twelve men were given intensity-modulated radiation therapy intensity-modulated radiation therapy See IMRT. and increasing doses of docetaxel for five consecutive weeks, which was followed by surgical removal of the prostate gland. They found that the participants tolerated the treatment well and were able to undergo surgery without any major complications. Specifically there were no rectal or ureteral ureteral pertaining to or emanating from the ureter. ureteral calculus ureterolith. ureteral distention ureterectasis. injuries or blood clots Blood Clots Definition A blood clot is a thickened mass in the blood formed by tiny substances called platelets. Clots form to stop bleeding, such as at the site of cut. in the legs. Examination of the tumour tissue after surgery showed the cancer margins, evidence of complete removal of all of the cancer, to be clean in 75 percent of patients, which is higher than was expected. Also, the PSA (Professional Services Automation) An information system designed to organize, track and manage all opportunities, work, resources, costs, revenues and invoices to improve the productivity and efficiency of the workforce. , or prostate-specific antigen levels, a predictor of prostate cancer recurrence, were undetectable after treatment in all patients. "Our study is the first-ever clinical trial in prostate cancer to combine radiation, chemotherapy and surgery given as a combination treatment before prostate surgery to potentially provide higher cure rates than traditional approaches with fewer side effects," said Dr Arthur Hung, M.D., co-investigator and Assistant Professor of Radiation Medicine in the OHSU Knight Cancer Institute. The findings were presented at 51st annual meeting of the American Society of Therapeutic Radiology and Oncology in Chicago. (ANI) Copyright 2009 Asian News International The Asian News International (ANI) agency provides multimedia news to China and 50 bureaus in India. It covers virtually all of South Asia since its foundation and presently claims, on its official website, to be the leading South Asia-wide news agency. (ANI) - All Rights Reserved. Provided by Syndigate.info an Albawaba.com company |
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