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Chemo 'may harm brains of patients'.



A CHEMOTHERAPY drug used to treat cancer patients could cause brain damage, researchers claim.

The 5-fluorouracil drug, known as 5-RU, destroyed brain cells which keep the nerves in working orders when given to laboratory mice.

It could explain why patients given chemotherapy sometimes complain of "chemo cheĀ·mo
n.
Chemotherapy or a chemotherapeutic treatment.
 brain" - memory loss, poor concentration and even seizures, impaired vision and dementia. In the past, they have been dismissed as due to fatigue, depression and anxiety.

Dr Mark Noble, of the University of Rochester The University of Rochester (UR) is a private, coeducational and nonsectarian research university located in Rochester, New York. The university is one of 62 elected members of the Association of American Universities.  Medical Centre, New York New York, state, United States
New York, Middle Atlantic state of the United States. It is bordered by Vermont, Massachusetts, Connecticut, and the Atlantic Ocean (E), New Jersey and Pennsylvania (S), Lakes Erie and Ontario and the Canadian province of
 State, said: "It is clear that, in some patients, chemotherapy appears to trigger a degenerative condition in the nervous system."

His team said that at least 82 per cent of breast cancer patients reported mental impairment after chemo. Martin Ledwick, of Cancer Research UK, said: "This research has taken place on mice and stem cells so it does not necessarily equate to real people's experiences."
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Publication:The Mirror (London, England)
Date:Apr 22, 2008
Words:149
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