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Chemical drink boosts exercise levels in mice with damaged hearts by 35pct.


London, February 10 (ANI): A group of French researchers believe that a chemical drink may reenergize heart attack patients by increasing the supply of oxygen to their damaged cardiac muscle cardiac muscle
n.
The muscle of the heart, consisting of anastomosing transversely striated muscle fibers formed of cells united at intercalated disks; the myocardium. Also called muscle of heart.
.

Jean-Marie Lehn Jean-Marie Lehn (born September 30, 1939) is a French chemist. He received the Nobel Prize together with Donald Cram and Charles Pedersen in 1987 for his work in Chemistry, particularly his synthesis of the cryptands.  and his colleagues, at the University of Strasbourg The University of Strasbourg in Strasbourg, Alsace, France, was divided in the 1970s into three separate institutions with a total of approximately 48,500 students as of 2007. , came to this conclusion after carrying out experiments on ailing mice, wherein the drink-formed by dissolving the drug myo-inositol trispyrophosphate (ITPP ITPP International TOVS Processing Package
ITPP Individual Training Plan Proposal
ITPP Integrated Test Program
) in water-boosted exercise levels in the animals by 35 per cent.

The researcher revealed that the drink had been designed to make haemoglobin haemoglobin or US hemoglobin
Noun

a protein in red blood cells that carries oxygen from the lungs to the tissues [Greek haima blood + Latin globus ball]

Noun 1.
 release more of its oxygen than normal.

They said that when it was given by injection into the abdomen, the subjects' exercise levels rose a massive 60 per cent.

"ITPP doesn't deliver oxygen itself, but makes haemoglobin able to release a larger amount of oxygen to tissues," the Sun quoted Lehn as saying.

He revealed that haemoglobin generally releases only 25 per cent of oxygen during one circuit of the body. But when ITPP binds to haemoglobin, he adds, it releases 35 per cent more than usual, boosting supplies of oxygen to tissues without people having to inhale any extra air.

The researcher even said that the effect from a single dose was found to last for almost a week, which means that the patient need not take ITPP every day.

Though the substance is not natural, it is said to be related to myo-inositol, which is found in rice and cereals.

Lehn hopes to begin clinical trials on humans "as soon as possible".

He, however, warned athletes against using the substance to enhance their performance.

"It could be very easily detected," New Scientist magazine quoted him as saying.

Lehn revealed that his team were continuing their research to determine exactly how ITPP interferes with haemoglobin to make it give up more oxygen.

A report on Lehn's study has been published in the journal Proceedings of the National Academy of Sciences The Proceedings of the National Academy of Sciences of the United States of America, usually referred to as PNAS, is the official journal of the United States National Academy of Sciences. . (ANI)

Copyright 2009 Asian News International The Asian News International (ANI) agency provides multimedia news to China and 50 bureaus in India. It covers virtually all of South Asia since its foundation and presently claims, on its official website, to be the leading South Asia-wide news agency.  (ANI) - All Rights Reserved.

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Publication:Asian News International
Date:Oct 5, 2009
Words:333
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