Chemex announces results of pilot study with masoprocol cream for reversal of symptoms of photoaged skin.FORT LEE, N.J.--(BUSINESS WIRE)--Nov. 1, 1994--Chemex Pharmaceuticals Inc. (NASDAQ NASDAQ in full National Association of Securities Dealers Automated Quotations U.S. market for over-the-counter securities. Established in 1971 by the National Association of Securities Dealers (NASD), NASDAQ is an automated quotation system that reports on :CHMX), on behalf of its joint venture with Block Drug Co., announced Tuesday the results of a pilot study to determine the safety and efficacy of its compound, CHX-100 (masoprocol cream- 0.25% to 2.5%). Sixty-four patients participated in a double-blinded study in which four groups of patients with mild to moderate photodamaged skin applied vehicle, 0.25%, 1.0% or 2.5% masoprocol cream once-a-day for up to twelve weeks. The results indicate that all three groups treated with masoprocol cream demonstrated improvement in overall severity of their photodamaged skin, while patients treated with vehicle did not show any improvement. These initial results indicate that masoprocol, in low concentrations, when applied topically, can improve the appearance of photodamaged skin. Photodamaged skin is a result of excessive sun exposure which damages skin cells resulting in pre-mature aging of the skin. The number and severity of dermal dermal /der·mal/ (der´mal) pertaining to the dermis or to the skin. der·mal or der·mic adj. Of or relating to the skin or dermis. adverse reactions adverse reactions, n.pl unfavorable reactions resulting from administration of a local anesthetic; responsible factors include the drug used, concentration, and route of administration. observed in the study were less frequent and milder than expected. However, the dermal side effect profile experienced by some patients was judged to be unacceptable for long term use for the treatment of photoaged skin. Accordingly, a new stable formulation formulation /for·mu·la·tion/ (for?mu-la´shun) the act or product of formulating. American Law Institute Formulation of masoprocol creams has been developed, which will be tested to determine if this new formulation will reduce the dermal side effects Side effects Effects of a proposed project on other parts of the firm. to an acceptable level. Additional human studies using the new formulations are planned to commence during the first quarter of 1995. Chemex is a leader in developing new prescription drugs prescription drug Prescription medication Pharmacology An FDA-approved drug which must, by federal law or regulation, be dispensed only pursuant to a prescription–eg, finished dose form and active ingredients subject to the provisos of the Federal Food, Drug, for the treatment of various skin diseases. CONTACT: Chemex Pharmaceuticals Inc., Fort Lee Len Stigliano, 201/944-1449 |
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