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Cetek Corporation Achieves Research Milestone Payment From Millennium Pharmaceuticals.


Business Editors and Health/Medical Writers

BIOWIRE2K

MARLBOROUGH, Mass.--(BW HealthWire)--Feb. 19, 2002

Cetek Corporation announced today that it has achieved a milestone under its research agreement with Millennium Pharmaceuticals Millennium Pharmaceuticals NASDAQ: MLNM is a biotechnology company based in the Cambridge, Massachusetts area of the United States of America. Founded in 1993, the company conducts research in various scientific areas, currently focusing on inflammation and oncology. , Inc. (Nasdaq:MLNM), and as a result Millennium has paid Cetek an undisclosed milestone payment. The Millennium-Cetek collaboration for which the milestone was achieved began in February 2001. The collaboration resulted in the discovery of several families of compounds from the Millennium library which Cetek identified as having binding activity.

"Our research collaboration with Millennium has been one of the most productive programs at Cetek," said Dr. James N. Little, President of Cetek. "This, Cetek's first milestone payment, demonstrates that our core Capillary Electrophoresis Capillary electrophoresis (CE), also known as capillary zone electrophoresis (CZE), can be used to separate ionic species by their charge and frictional forces. In traditional electrophoresis, electrically charged analytes move in a conductive liquid medium under the  (CE) screening assay is a very powerful tool in matching drugs with today's new genomic genomic

pertaining to a genome.


genomic clone
see clone.

genomic DNA
the DNA sequences making up the genome of an individual.

genomic library
see gene bank.
 targets. Scientists from Millennium and Cetek worked well together to push this program quickly to the lead optimization optimization

Field of applied mathematics whose principles and methods are used to solve quantitative problems in disciplines including physics, biology, engineering, and economics.
 stage."

Cetek has demonstrated that its core CE Assay is able to efficiently identify and rank the affinity of synthetic and natural product small molecules to therapeutic target proteins in a high-throughput environment. Cetek has screened over 6 million compounds against 120 targets in the last two years of operation. Cetek has doubled its screening capacity over the last three months to accommodate increased demand in contract screening and to accommodate demand from the Cetek Natural Products program. Ongoing screening collaborations at Cetek include: Pharmacia, Genome genome: see genetics.
genome

all the genetic content contained within an organism. An organism's genome is made up of molecules of deoxyribonucleic acid (DNA) that form long strands that are tightly wound into chromosomes, which are found in the
 Therapeutics therapeutics

Treatment and care to combat disease or alleviate pain or injury. Its tools include drugs, surgery, radiation therapy, mechanical devices, diet, and psychiatry.
, Lexicon Genetics, Millennium Pharmaceuticals, Essential Therapeutics, Johnson & Johnson and Schering-Plough plus others in North America North America, third largest continent (1990 est. pop. 365,000,000), c.9,400,000 sq mi (24,346,000 sq km), the northern of the two continents of the Western Hemisphere. , Europe and Japan.

About Cetek

Cetek Corporation is a drug discovery company that is unlocking new reservoirs of natural compound diversity for the creation of novel therapeutics. Cetek integrates expertise in automation, engineering and novel strategies in natural product chemistry to utilize its capillary electrophoresis technology as a highly sensitive Adj. 1. highly sensitive - readily affected by various agents; "a highly sensitive explosive is easily exploded by a shock"; "a sensitive colloid is readily coagulated"  and robust technology for high throughput screening and compound isolation. Cetek also employs its automated CE Assay(TM) to provide contract research for pharmaceutical and biotechnology partners to advance their own synthetic and natural product drug discovery programs. Visit Cetek's website at http://www.cetek.com.

For additional information, visit Cetek's website at http://www.cetek.com or contact Dr. James N. Little, President, at (508) 229-8900 or j.little@cetek.com.
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Publication:Business Wire
Geographic Code:1USA
Date:Feb 19, 2002
Words:372
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