Cenix BioScience and Merck KGaA Sign Framework Agreement for RNAi-Based Drug Discovery.DRESDEN, Germany -- Cenix BioScience GmbH (Dresden), the leading specialist in advanced RNA interference RNA interference n. A process in which the introduction of double-stranded RNA into a cell inhibits the expression of genes. (RNAi)-based research services, and Merck KGaA This article needs sources or references that appear in reliable, third-party publications. Alone, primary sources and sources affiliated with the subject of this article are not sufficient for an accurate encyclopedia article. (Darmstadt, Germany), a leading global pharmaceutical company, today announced that they have signed a framework research agreement securing Cenix services to enhance and accelerate Merck target discovery and validation efforts in oncology oncology /on·col·o·gy/ (ong-kol´ah-je) the sum of knowledge regarding tumors; the study of tumors. on·col·o·gy n. , with an option to expand in several human disease programs. Cenix will apply its well-established expertise combining high throughput (HT), genome-scale screening applications of RNAi with high content phenotypic phe·no·type n. 1. a. The observable physical or biochemical characteristics of an organism, as determined by both genetic makeup and environmental influences. b. analyses in cultured human cells to discover and validate new therapeutic targets, using assays co-designed with Merck scientists. By yielding direct and highly predictive insights into the cellular functions and loss-of-function phenotypes of analyzed genes, this RNAi-based approach will enable Merck to efficiently select targets with higher confidence for driving their drug development programs. "As this project represents a very careful and well-thought-out design process, we are delighted to undertake it with Merck" noted Dr. Christophe Echeverri, CEO/CSO of Cenix BioScience. "We look forward to vindicating the recognition and trust shown by our Merck colleagues in allowing Cenix to provide them with the most advanced and mature technology, infrastructure and expertise for performing efficient and fast HT-RNAi-based drug discovery." About Cenix BioScience GmbH Cenix BioScience GmbH is a pioneer and leader in high throughput, genome-driven applications of RNA interference for the discovery and validation of new therapeutic drug targets. Founded in 1999 as the first biotechnology company specializing exclusively in HT-RNAi, Cenix has accumulated unparalleled depth and breadth of experience in this field, combining high content phenotypic analyses with proprietary genome-wide RNAi libraries for use in key experimental systems, including a wide range of human and rodent rodent, member of the mammalian order Rodentia, characterized by front teeth adapted for gnawing and cheek teeth adapted for chewing. The Rodentia is by far the largest mammalian order; nearly half of all mammal species are rodents. cells. Cenix is now making its unique expertise accessible to industry and academic researchers through highly customizable research and consulting services Noun 1. consulting service - service provided by a professional advisor (e.g., a lawyer or doctor or CPA etc.) service - work done by one person or group that benefits another; "budget separately for goods and services" . Please contact Cenix or visit the company's web site www.cenix-bioscience.com for more information. About Merck KGaA Merck is a global pharmaceutical and chemical company with sales of EUR EUR In currencies, this is the abbreviation for the Euro. Notes: The currency market, also known as the Foreign Exchange market, is the largest financial market in the world, with a daily average volume of over US $1 trillion. 5.9 billion in 2005, a history that began in 1668, and a future shaped by 29,958 employees in 55 countries. Its success is characterized by innovations from entrepreneurial employees. Merck's operating activities come under the umbrella of Merck KGaA, in which the Merck family Friedrich Jacob Merck purchased the second town pharmacy in Darmstadt, known as the Engel-Apotheke or Angel Pharmacy. When Friedrich died, the pharmacy was passed on to his nephew and ever since has gone from father to son. holds a 73% interest and free shareholders own the remaining 27%. In 1917 the U.S. subsidiary Merck & Co. was expropriated ex·pro·pri·ate tr.v. ex·pro·pri·at·ed, ex·pro·pri·at·ing, ex·pro·pri·ates 1. To deprive of possession: expropriated the property owners who lived in the path of the new highway. and has been an independent company ever since. www.cenix-bioscience.com Cenix and the Cenix BioScience logo are registered trademarks of Cenix BioScience GmbH. |
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