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Celsion Announces Data Using Pulsed-High Intensity Focused Ultrasound and ThermoDox(TM) to be Presented at the 2007 Society of International Radiology Meeting.


COLUMBIA, Md. -- CELSION CORPORATION (AMEX AMEX

See: American Stock Exchange
:CLN) today reported that Dr. Sergio Dromi (Research Fellow, Diagnostic Radiology Department, NIH Clinical Center, Bethesda, MD) will present data on Pulsed-High Intensity Focused Ultrasound (HIFU HIFU High-intensity focused ultrasound Surgery A method that focuses ultrasound to heat/ablate target tissue without injuring surrounding structures. See Sonablate 200™. ) enhanced delivery of tissue levels of doxorubicin and resultant tumor growth inhibition when using heat sensitive liposomes encapsulating doxorubicin (ThermoDox). The oral presentation will be on Monday, March 5th between 8-10 a.m. at the Annual Meeting of the Society of Interventional Radiology in Seattle, WA. The study was conducted under the leadership of Dr. Steven Libutti,( )(Surgery Branch, NCI) with Dr. Brad Wood, MD and Dr. Victor Frenkel, PhD (Diagnostic Radiology Department & Molecular Imaging Laboratory, NIH Clinical Center, Bethesda, MD).

Mr. Michael Tardugno, Celsion's President of Chief Executive Officer, commented, "This study further demonstrates the ability of our heat activated liposome to deliver high levels of anticancer drugs to tumor tissue. With this HIFU based study, in addition to our on-going studies using radiofrequency ablation and microwave energy, we have further demonstrated that ThermoDox is indifferent to the heating medium triggering the drug release. We are delighted to support this exciting research under our CRADA with the NCI and the NIH Clinical Center. NIH and Celsion are collaborating on a number of pre-clinical and clinical projects. These results further underscore the utility and versatility of our platform technology. This work will be used to refine tumor targeting and ultimately to improve the efficacy of drugs using our heat activated delivery system."

About Celsion: The Prolieve Thermodilatation system is a minimally invasive transurethral microwave system which combines a transurethral microwave thermotherapy device with pressure applied by a balloon catheter.

Prolieve is marketed, in the United States, under an exclusive distribution agreement, with Boston Scientific Corporation.

Celsion has research, license or commercialization agreements with leading institutions such as the National Institutes of Health, Duke University Medical Center, Massachusetts Institute of Technology Massachusetts Institute of Technology, at Cambridge; coeducational; chartered 1861, opened 1865 in Boston, moved 1916. It has long been recognized as an outstanding technological institute and its Sloan School of Management has notable programs in business, , Harbor UCLA Medical Center UCLA Medical Center is a hospital located on the campus of the University of California, Los Angeles in Los Angeles, California. It is rated as one of the top three hospitals in the United States and is the top hospital on the West Coast according to US News & World Report. , Montefiore Medical Center Montefiore Medical Center, in the Bronx, New York, is the university hospital of the Albert Einstein College of Medicine. The hospital, named after Moses Montefiore, is one of the 50 largest employers in New York State [1].  and Memorial Sloan-Kettering Cancer Center The Memorial Sloan-Kettering Cancer Center (MSKCC) in New York City is a cancer treatment and research institution founded in 1884 as the New York Cancer Hospital. The main campus is located at 1275 York Avenue, between 67th and 68th Streets, with other locations in New  in New York City New York City: see New York, city.
New York City

City (pop., 2000: 8,008,278), southeastern New York, at the mouth of the Hudson River. The largest city in the U.S.
, Roswell Park Cancer Institute The Roswell Park Cancer Institute is a cancer research and treatment center located in Buffalo, New York. Founded in 1898 by Dr. Roswell Park, it was the first dedicated medical facility for cancer treatment and research in the United States.  in Buffalo, New York, and Duke University. For more information on Celsion, visit our website: http://www.celsion.com.

Celsion wishes to inform readers that forward-looking statements in this release are made pursuant to the "safe harbor" provisions of the Private Securities Litigation Reform Act The Private Securities Litigation Reform Act of 1995 (PSLRA) implemented several significant substantive changes affecting certain cases brought under the federal securities laws, including changes related to pleading, discovery, liability, class representation and awards fees and  of 1995. Readers are cautioned that such forward-looking statements involve risks and uncertainties including, without limitation, unforeseen changes in the course of research and development activities and in clinical trials by others; possible acquisitions of other technologies, assets or businesses; possible actions by customers, suppliers, competitors, regulatory authorities; and other risks detailed from time to time in the Company's periodic reports filed with the Securities and Exchange Commission.
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Copyright 2007, Gale Group. All rights reserved. Gale Group is a Thomson Corporation Company.

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Publication:Business Wire
Date:Mar 5, 2007
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