Cellular signaling and innate immune responses to RNA virus infections.9781555814366 Cellular signaling and innate immune responses to RNA virus infections. Ed. by Allan R. Brasier et al. ASM (1) (Association for Systems Management) An international membership organization based in Cleveland, Ohio. Founded in 1947 and disbanded in 1996, it sponsored conferences in all phases of administrative systems and management. Press 2009 436 pages $139.95 Hardcover QR395 Focusing on early host responses to RNA virus infections, these contributors examine the mechanisms adopted by these viruses to evade early host antiviral responses. Acknowledging the enormous expansion of this field as researchers have identified high resolution structures of pattern recognition receptors, contributors detail how cells sense signals to activate the innate immune response. Their topics include the role of toll-like receptors in the inmate immune response to RNA viruses, mitochondrial mitochondrial pertaining to mitochondria. mitochondrial RNAs a unique set of tRNAs, mRNAs, rRNAs, transcribed from mitochondrial DNA by a mitochondrial-specific RNA polymerase, that account for about 4% of the total cell RNA that antiviral signaling, the Jak-Stat pathway in response to virus infection, interferons and antiviral action, and human genetic factors involved in viral pathogenesis. They also focus on the activation and evasion of host antiviral signaling pathways by detailing RNA virus families, filoviruses, suppression of innate immunity, paramyxovirus Paramyxovirus A subgroup of myxoviruses that includes the viruses of mumps, measles, parainfluenza, respiratory syncytial (RS) disease, and Newcastle disease. and orthomyxoviruses, arenaviruses, picornaviruses, togaviruses, coronaviruses and innate immune responses elicited by reovirus reovirus Any of a small group of animal and plant viruses that appear spheroidal and contain a core of RNA. Among the best-known genera are Orthoreovirus, Orbivirus, Rotavirus, and Phytoreovirus. The first three infect animals; the last can destroy rice, corn, and other crops. and rotavirus rotavirus /ro·ta·vi·rus/ (ro´tah-vi?rus) any member of the genus Rotavirus. ro´taviral Rotavirus /Ro·ta·vi·rus/ (ro´tah-vi?rus . ([c]20082005 Book News, Inc., Portland, OR) |
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